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BMC Nephrol. 2013 Feb 22;14:46. doi: 10.1186/1471-2369-14-46.

Prevalence of chronic kidney disease in patients with type 2 diabetes in Spain: PERCEDIME2 study.

Collaborators (86)

Alum Bou A, Angullo Martínez E, Arnaiz Arroyo J, Artola Menendez S, Avila Lachica L, Barquilla García A, Barrot de la Puente J, Barutell Rubio L, Belinchón Sánchez M, Benito Badorrey B, Bobe Molina I, Bosch Costabella R, Buil Cosiales P, Carramiñana Barrera F, Carrillo Fernández L, Carrión Valero L, Casaseca Garcia P, Colt Loredana C, Comas Samper J, Cuevas Lopez J, De la Sen C, Díez Espino J, Domínguez Coello S, Domínguez Navarro D, Egocheaga Cabello I, Ferrer Menduiña X, Franch Nadal J, García Aparicio JM, Garcia Gallego F, García Soidán FJ, Garrido Redondo N, Gómez García C, Gomez Gonzalez L, Gonzalez Pastor C, Granero Fernandez E, Grau Bartomeu J, Guruchaga Arcelus M, Gutiérrez Almarza M, Gutierrez Perez A, Hernandez Monroy A, Hidalgo Ortiz M, Iglesias González R, Igual Fraile D, Llussà Arboix J, Marín Becerra T, Martín Manzano JL, Martínez Sierra C, Massana Raurich A, Massó Orozco J, Mata Cases M, Merino Pacho J, Millaruelo Trillo JM, Morales Escobar F, Modroño Freire M, Monzon Guerra A, Muguruza Valdeolmillos J, Mundet Tuduri X, Mur Marti T, Nogales Aguado P, Ortega Ríos FJ, Otero Serra X, Otzet Gramunt I, Pascual De la Pisa B, Patitucci Gómez F, Pinto Rivero M, Piulats Egea N, Pujol Martínez R, Quindimil Vázquez J, Robles Agüero E, Rodero Nuño M, Rodríguez Poncelas A, Ruiz Tamayo I, Sagredo Perez J, Sanchez Cabrero LG, Sangrós González FJ, Sanz Rebollo G, Sedano Garcia JI, Serra Laguarta M, Serrano Martin R, Socias Buades I, Torres Baile JL, Trenchs Rodriguez M, Ulibarri del Portillo J, Vazquez de Prada I, Vergara Fernández I, Villaro Gabarros M.

Author information

  • 1EAP Anglès, Girona, Spain.

Abstract

BACKGROUND:

The objective of this study was to determinate the prevalence of chronic kidney disease (CKD) and the different stages of CKD in patients with type 2 diabetes mellitus (DM2) treated in primary care consults in Spain.

METHODS:

A national cross-sectional study was performed in primary care consults. The following data were collected: demographic and anthropometric information; list of present cardiovascular risk factors (CVRF); previous macrovascular and microvascular disease history; physical examination and analytical data from the previous 12 months, including the urine albumin-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) to evaluate renal function.

RESULTS:

With regard to the patients, 27.9% presented some degree of CKD as follows: 3.5% with stage 1; 6.4% with stage 2; 16.8% with stage 3 (11.6% with stage 3A and 5.2% with stage 3B); and 1.2% with stages 4 and 5. The prevalence of patients with UACR ≥ 30 mg/g was 15.4% (13% microalbuminuria and 2.4% macroalbuminuria). Renal impairment (RI) was found in 206 patients (18%) of whom 133 patients (64.6%) was stage 3A, 60 patients (29.1%) was stage 3B and 13 patients (6.3%) stages 4 and 5. Among patients with RI, 143 patients (69.4%) had normoalbuminuria. The following variables were significantly associated with CKD: age; sex (women); systolic arterial blood pressure (SABP) ≥ 150 mmHg; and a previous history of cardiovascular disease.

CONCLUSIONS:

The results showed that the prevalence for any type of CKD was 27.9%. A systematic determination of UACR and eGFR may contribute to an early diagnosis, thus allowing intervention during the initial stages of the disease when treatment is more efficient.

PMID:
23433046
[PubMed - indexed for MEDLINE]
PMCID:
PMC3598539
Free PMC Article
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