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Results: 1 to 20 of 38

1.

Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin.

Johnson-Kerner BL, Ahmad FS, Diaz AG, Greene JP, Gray SJ, Samulski RJ, Chung WK, Van Coster R, Maertens P, Noggle SA, Henderson CE, Wichterle H.

Hum Mol Genet. 2015 Mar 1;24(5):1420-31. doi: 10.1093/hmg/ddu556. Epub 2014 Nov 4.

PMID:
25398950
2.

Biology of adeno-associated viral vectors in the central nervous system.

Murlidharan G, Samulski RJ, Asokan A.

Front Mol Neurosci. 2014 Sep 19;7:76. doi: 10.3389/fnmol.2014.00076. eCollection 2014. Review.

3.

Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs.

Pleticha J, Heilmann LF, Evans CH, Asokan A, Samulski RJ, Beutler AS.

Mol Pain. 2014 Sep 2;10:54. doi: 10.1186/1744-8069-10-54. Review.

4.

Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure.

Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, Samulski RJ, Sigg DC, Weber T, Kranias EG, Hajjar RJ.

Mol Ther. 2014 Dec;22(12):2038-45. doi: 10.1038/mt.2014.127. Epub 2014 Jul 15.

PMID:
25023328
5.

Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency.

Shen S, Horowitz ED, Troupes AN, Brown SM, Pulicherla N, Samulski RJ, Agbandje-McKenna M, Asokan A.

J Biol Chem. 2013 Oct 4;288(40):28814-23. doi: 10.1074/jbc.M113.482380. Epub 2013 Aug 12.

6.

Oversized AAV transductifon is mediated via a DNA-PKcs-independent, Rad51C-dependent repair pathway.

Hirsch ML, Li C, Bellon I, Yin C, Chavala S, Pryadkina M, Richard I, Samulski RJ.

Mol Ther. 2013 Dec;21(12):2205-16. doi: 10.1038/mt.2013.184. Epub 2013 Aug 13.

7.

Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model.

Redmond DE Jr, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR Jr.

Mol Ther. 2013 Dec;21(12):2160-8. doi: 10.1038/mt.2013.180. Epub 2013 Aug 5.

8.

Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration.

Gray SJ, Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ.

Curr Protoc Neurosci. 2011 Oct;Chapter 4:Unit 4.17. doi: 10.1002/0471142301.ns0417s57.

9.

Overexpression of SOD in retina: need for increase in H2O2-detoxifying enzyme in same cellular compartment.

Usui S, Oveson BC, Iwase T, Lu L, Lee SY, Jo YJ, Wu Z, Choi EY, Samulski RJ, Campochiaro PA.

Free Radic Biol Med. 2011 Oct 1;51(7):1347-54. doi: 10.1016/j.freeradbiomed.2011.06.010. Epub 2011 Jul 5.

10.

Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity.

Goudy KS, Johnson MC, Garland A, Li C, Samulski RJ, Wang B, Tisch R.

Eur J Immunol. 2011 May;41(5):1480-90. doi: 10.1002/eji.201040890. Epub 2011 Apr 20.

11.

Transient demyelination increases the efficiency of retrograde AAV transduction.

Hollis ER 2nd, Jamshidi P, Lorenzana AO, Lee JK, Gray SJ, Samulski RJ, Zheng B, Tuszynski MH.

Mol Ther. 2010 Aug;18(8):1496-500. doi: 10.1038/mt.2010.97. Epub 2010 May 25.

12.

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys.

Buie LK, Rasmussen CA, Porterfield EC, Ramgolam VS, Choi VW, Markovic-Plese S, Samulski RJ, Kaufman PL, BorrĂ¡s T.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):236-48. doi: 10.1167/iovs.09-3847. Epub 2009 Aug 13.

13.

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.

Li W, Asokan A, Wu Z, Van Dyke T, DiPrimio N, Johnson JS, Govindaswamy L, Agbandje-McKenna M, Leichtle S, Redmond DE Jr, McCown TJ, Petermann KB, Sharpless NE, Samulski RJ.

Mol Ther. 2008 Jul;16(7):1252-60. doi: 10.1038/mt.2008.100. Epub 2008 May 20.

14.

Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration.

Choi VW, Asokan A, Haberman RA, McCown TJ, Samulski RJ.

Curr Protoc Neurosci. 2006 May;Chapter 4:Unit 4.17. doi: 10.1002/0471142301.ns0417s35.

PMID:
18428636
15.

Production of recombinant adeno-associated viral vectors.

Choi VW, Asokan A, Haberman RA, Samulski RJ.

Curr Protoc Hum Genet. 2007 Apr;Chapter 12:Unit 12.9. doi: 10.1002/0471142905.hg1209s53.

PMID:
18428408
16.

Production of recombinant adeno-associated viral vectors for in vitro and in vivo use.

Choi VW, Asokan A, Haberman RA, Samulski RJ.

Curr Protoc Mol Biol. 2007 Apr;Chapter 16:Unit 16.25. doi: 10.1002/0471142727.mb1625s78. Review.

PMID:
18265393
17.

Efficient retrograde neuronal transduction utilizing self-complementary AAV1.

Hollis ER 2nd, Kadoya K, Hirsch M, Samulski RJ, Tuszynski MH.

Mol Ther. 2008 Feb;16(2):296-301. doi: 10.1038/sj.mt.6300367. Epub 2007 Nov 27.

PMID:
18223548
18.

Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction.

Zhong L, Zhou X, Li Y, Qing K, Xiao X, Samulski RJ, Srivastava A.

Mol Ther. 2008 Feb;16(2):290-5. Epub 2007 Dec 18.

PMID:
18087261
19.

Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose.

Wu Z, Sun J, Zhang T, Yin C, Yin F, Van Dyke T, Samulski RJ, Monahan PE.

Mol Ther. 2008 Feb;16(2):280-9. Epub 2007 Dec 4.

PMID:
18059373
20.

Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction.

Wang J, Xie J, Lu H, Chen L, Hauck B, Samulski RJ, Xiao W.

Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13104-9. Epub 2007 Jul 30.

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