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Results: 1 to 20 of 49

1.

Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.

Lu YC, Yao X, Crystal JS, Li YF, El-Gamil M, Gross C, Davis L, Dudley ME, Yang JC, Samuels Y, Rosenberg SA, Robbins PF.

Clin Cancer Res. 2014 Jul 1;20(13):3401-10. doi: 10.1158/1078-0432.CCR-14-0433.

PMID:
24987109
[PubMed - in process]
2.

A highly recurrent RPS27 5'UTR mutation in melanoma.

Dutton-Regester K, Gartner JJ, Emmanuel R, Qutob N, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Scolyer RA, Mann GJ, Thompson JF, Hayward NK, Samuels Y.

Oncotarget. 2014 May 30;5(10):2912-7.

PMID:
24913145
[PubMed - in process]
Free PMC Article
3.

Somatic Mutation of GRIN2A in Malignant Melanoma Results in Loss of Tumor Suppressor Activity via Aberrant NMDAR Complex Formation.

Prickett TD, Zerlanko BJ, Hill VK, Gartner JJ, Qutob N, Jiang J, Simaan M, Wunderlich J, Gutkind JS, Rosenberg SA, Samuels Y.

J Invest Dermatol. 2014 Apr 16. doi: 10.1038/jid.2014.190. [Epub ahead of print]

PMID:
24739903
[PubMed - as supplied by publisher]
4.

ERBB4 mutation analysis: emerging molecular target for melanoma treatment.

Lau C, Killian KJ, Samuels Y, Rudloff U.

Methods Mol Biol. 2014;1102:461-80. doi: 10.1007/978-1-62703-727-3_24.

PMID:
24258993
[PubMed - indexed for MEDLINE]
5.

Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin.

Prickett TD, Zerlanko B, Gartner JJ, Parker SC, Dutton-Regester K, Lin JC, Teer JK, Wei X, Jiang J; NISC Comparative Sequencing Program, Chen G, Davies MA, Gershenwald JE, Robinson W, Robinson S, Hayward NK, Rosenberg SA, Margulies EH, Samuels Y.

J Invest Dermatol. 2014 Feb;134(2):452-60. doi: 10.1038/jid.2013.365. Epub 2013 Sep 5.

PMID:
24008424
[PubMed - indexed for MEDLINE]
6.

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma.

Gartner JJ, Parker SC, Prickett TD, Dutton-Regester K, Stitzel ML, Lin JC, Davis S, Simhadri VL, Jha S, Katagiri N, Gotea V, Teer JK, Wei X, Morken MA, Bhanot UK; NISC Comparative Sequencing Program, Chen G, Elnitski LL, Davies MA, Gershenwald JE, Carter H, Karchin R, Robinson W, Robinson S, Rosenberg SA, Collins FS, Parmigiani G, Komar AA, Kimchi-Sarfaty C, Hayward NK, Margulies EH, Samuels Y.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13481-6. doi: 10.1073/pnas.1304227110. Epub 2013 Jul 30. Erratum in: Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):563.

PMID:
23901115
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The genetics of melanoma: recent advances.

Hill VK, Gartner JJ, Samuels Y, Goldstein AM.

Annu Rev Genomics Hum Genet. 2013;14:257-79. doi: 10.1146/annurev-genom-091212-153429. Epub 2013 Jul 12. Review.

PMID:
23875803
[PubMed - indexed for MEDLINE]
8.

Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.

Lu YC, Yao X, Li YF, El-Gamil M, Dudley ME, Yang JC, Almeida JR, Douek DC, Samuels Y, Rosenberg SA, Robbins PF.

J Immunol. 2013 Jun 15;190(12):6034-42. doi: 10.4049/jimmunol.1202830. Epub 2013 May 20.

PMID:
23690473
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells.

Robbins PF, Lu YC, El-Gamil M, Li YF, Gross C, Gartner J, Lin JC, Teer JK, Cliften P, Tycksen E, Samuels Y, Rosenberg SA.

Nat Med. 2013 Jun;19(6):747-52. doi: 10.1038/nm.3161. Epub 2013 May 5.

PMID:
23644516
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Shimmer: detection of genetic alterations in tumors using next-generation sequence data.

Hansen NF, Gartner JJ, Mei L, Samuels Y, Mullikin JC.

Bioinformatics. 2013 Jun 15;29(12):1498-503. doi: 10.1093/bioinformatics/btt183. Epub 2013 Apr 24.

PMID:
23620360
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma.

Gartner JJ, Davis S, Wei X, Lin JC, Trivedi NS, Teer JK; NISC Comparative Sequencing Program, Meltzer PS, Rosenberg SA, Samuels Y.

BMC Genomics. 2012 Sep 24;13:505. doi: 10.1186/1471-2164-13-505.

PMID:
23006843
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mutational signatures of de-differentiation in functional non-coding regions of melanoma genomes.

Parker SC, Gartner J, Cardenas-Navia I, Wei X, Ozel Abaan H, Ajay SS, Hansen NF, Song L, Bhanot UK, Killian JK, Gindin Y, Walker RL, Meltzer PS, Mullikin JC, Furey TS, Crawford GE, Rosenberg SA, Samuels Y, Margulies EH.

PLoS Genet. 2012;8(8):e1002871. doi: 10.1371/journal.pgen.1002871. Epub 2012 Aug 9.

PMID:
22912592
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Molecular pathways: dysregulated glutamatergic signaling pathways in cancer.

Prickett TD, Samuels Y.

Clin Cancer Res. 2012 Aug 15;18(16):4240-6. doi: 10.1158/1078-0432.CCR-11-1217. Epub 2012 May 30. Review.

PMID:
22648273
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Delving into somatic variation in sporadic melanoma.

Walia V, Mu EW, Lin JC, Samuels Y.

Pigment Cell Melanoma Res. 2012 Mar;25(2):155-70. doi: 10.1111/j.1755-148X.2012.00976.x. Epub 2012 Feb 13. Review.

PMID:
22260482
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, Samuels Y.

Nat Genet. 2011 Sep 25;43(11):1119-26. doi: 10.1038/ng.950.

PMID:
21946352
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mutational inactivation of STAG2 causes aneuploidy in human cancer.

Solomon DA, Kim T, Diaz-Martinez LA, Fair J, Elkahloun AG, Harris BT, Toretsky JA, Rosenberg SA, Shukla N, Ladanyi M, Samuels Y, James CD, Yu H, Kim JS, Waldman T.

Science. 2011 Aug 19;333(6045):1039-43. doi: 10.1126/science.1203619.

PMID:
21852505
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.

Wei X, Moncada-Pazos A, Cal S, Soria-Valles C, Gartner J, Rudloff U, Lin JC; NISC Comparative Sequencing Program, Rosenberg SA, López-Otín C, Samuels Y.

Hum Mutat. 2011 Jun;32(6):E2148-75. doi: 10.1002/humu.21477. Epub 2011 Feb 24.

PMID:
21618342
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Exome sequencing identifies GRIN2A as frequently mutated in melanoma.

Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, Davis S; NISC Comparative Sequencing Program, Stemke-Hale K, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Samuels Y.

Nat Genet. 2011 May;43(5):442-6. doi: 10.1038/ng.810. Epub 2011 Apr 15.

PMID:
21499247
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.

Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P; NISC Comparative Sequencing Program, Rosenberg SA, Davies MA, Gershenwald JE, López-Otín C, Samuels Y.

Mol Cancer Res. 2010 Nov;8(11):1513-25. doi: 10.1158/1541-7786.MCR-10-0262. Epub 2010 Oct 13.

PMID:
21047771
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Analysis of the genome to personalize therapy for melanoma.

Davies MA, Samuels Y.

Oncogene. 2010 Oct 14;29(41):5545-55. doi: 10.1038/onc.2010.323. Epub 2010 Aug 9. Review.

PMID:
20697348
[PubMed - indexed for MEDLINE]
Free PMC Article

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