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Results: 1 to 20 of 100

1.

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.

Ebrahimkhani MR, Daneshmand A, Mazumder A, Allocca M, Calvo JA, Abolhassani N, Jhun I, Muthupalani S, Ayata C, Samson LD.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4878-86. doi: 10.1073/pnas.1413582111. Epub 2014 Oct 27.

PMID:
25349415
[PubMed - in process]
2.

DNA glycosylase activity and cell proliferation are key factors in modulating homologous recombination in vivo.

Kiraly O, Gong G, Roytman MD, Yamada Y, Samson LD, Engelward BP.

Carcinogenesis. 2014 Nov;35(11):2495-502. doi: 10.1093/carcin/bgu177. Epub 2014 Aug 25.

PMID:
25155011
[PubMed - in process]
3.

Repair of endogenous DNA base lesions modulate lifespan in mice.

Meira LB, Calvo JA, Shah D, Klapacz J, Moroski-Erkul CA, Bronson RT, Samson LD.

DNA Repair (Amst). 2014 Sep;21:78-86. doi: 10.1016/j.dnarep.2014.05.012. Epub 2014 Jun 30.

PMID:
24994062
[PubMed - in process]
4.

Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research.

Nagel ZD, Chaim IA, Samson LD.

DNA Repair (Amst). 2014 Jul;19:199-213. doi: 10.1016/j.dnarep.2014.03.009. Epub 2014 Apr 26.

PMID:
24780560
[PubMed - in process]
5.

Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.

Nagel ZD, Margulies CM, Chaim IA, McRee SK, Mazzucato P, Ahmad A, Abo RP, Butty VL, Forget AL, Samson LD.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1823-32. doi: 10.1073/pnas.1401182111. Epub 2014 Apr 22.

PMID:
24757057
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids in cellular recovery after quinone exposure.

Svensson JP, QuirĂ³s Pesudo L, McRee SK, Adeleye Y, Carmichael P, Samson LD.

PLoS One. 2013 Sep 9;8(9):e73736. doi: 10.1371/journal.pone.0073736. eCollection 2013.

PMID:
24040048
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae.

Mazumder A, Pesudo LQ, McRee S, Bathe M, Samson LD.

Nucleic Acids Res. 2013 Nov 1;41(20):9310-24. doi: 10.1093/nar/gkt715. Epub 2013 Aug 9.

PMID:
23935119
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis.

Fu D, Jordan JJ, Samson LD.

Genes Dev. 2013 May 15;27(10):1089-100. doi: 10.1101/gad.215533.113. Epub 2013 May 10.

PMID:
23666923
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae.

Vahey MD, Quiros Pesudo L, Svensson JP, Samson LD, Voldman J.

Lab Chip. 2013 Jul 21;13(14):2754-63. doi: 10.1039/c3lc50162k.

PMID:
23661198
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.

Calvo JA, Moroski-Erkul CA, Lake A, Eichinger LW, Shah D, Jhun I, Limsirichai P, Bronson RT, Christiani DC, Meira LB, Samson LD.

PLoS Genet. 2013 Apr;9(4):e1003413. doi: 10.1371/journal.pgen.1003413. Epub 2013 Apr 4.

PMID:
23593019
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB).

van Loon B, Samson LD.

DNA Repair (Amst). 2013 Mar 1;12(3):177-87. doi: 10.1016/j.dnarep.2012.11.009. Epub 2013 Jan 3.

PMID:
23290262
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage.

Mazumder A, Tummler K, Bathe M, Samson LD.

Mol Cell Biol. 2013 Feb;33(3):635-42. doi: 10.1128/MCB.01020-12. Epub 2012 Nov 26.

PMID:
23184665
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation.

Noonan EM, Shah D, Yaffe MB, Lauffenburger DA, Samson LD.

Integr Biol (Camb). 2012 Oct;4(10):1237-55.

PMID:
22892544
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

DNA repair is indispensable for survival after acute inflammation.

Calvo JA, Meira LB, Lee CY, Moroski-Erkul CA, Abolhassani N, Taghizadeh K, Eichinger LW, Muthupalani S, Nordstrand LM, Klungland A, Samson LD.

J Clin Invest. 2012 Jul 2;122(7):2680-9. doi: 10.1172/JCI63338. Epub 2012 Jun 11.

PMID:
22684101
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Identification of novel human damage response proteins targeted through yeast orthology.

Svensson JP, Fry RC, Wang E, Somoza LA, Samson LD.

PLoS One. 2012;7(5):e37368. doi: 10.1371/journal.pone.0037368. Epub 2012 May 16.

PMID:
22615993
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation.

Olipitz W, Wiktor-Brown D, Shuga J, Pang B, McFaline J, Lonkar P, Thomas A, Mutamba JT, Greenberger JS, Samson LD, Dedon PC, Yanch JC, Engelward BP.

Environ Health Perspect. 2012 Aug;120(8):1130-6. doi: 10.1289/ehp.1104294. Epub 2012 Apr 26.

PMID:
22538203
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress.

Tentner AR, Lee MJ, Ostheimer GJ, Samson LD, Lauffenburger DA, Yaffe MB.

Mol Syst Biol. 2012 Jan 31;8:568. doi: 10.1038/msb.2012.1.

PMID:
22294094
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Balancing repair and tolerance of DNA damage caused by alkylating agents.

Fu D, Calvo JA, Samson LD.

Nat Rev Cancer. 2012 Jan 12;12(2):104-20. doi: 10.1038/nrc3185. Review.

PMID:
22237395
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase.

Setser JW, Lingaraju GM, Davis CA, Samson LD, Drennan CL.

Biochemistry. 2012 Jan 10;51(1):382-90. doi: 10.1021/bi201484k. Epub 2011 Dec 20.

PMID:
22148158
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects.

Valiathan C, McFaline JL, Samson LD.

DNA Repair (Amst). 2012 Jan 2;11(1):92-8. doi: 10.1016/j.dnarep.2011.11.002. Epub 2011 Nov 30.

PMID:
22133811
[PubMed - indexed for MEDLINE]
Free PMC Article

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