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Cytocidal activities of topoisomerase 1 inhibitors and 5-azacytidine against pheochromocytoma/paraganglioma cells in primary human tumor cultures and mouse cell lines.

Powers JF, Korgaonkar PG, Fliedner S, Giubellino A, Pacak K, Sahagian GG, Tischler AS.

PLoS One. 2014 Feb 7;9(2):e87807. doi: 10.1371/journal.pone.0087807. eCollection 2014. Erratum in: PLoS One. 2014;9(3):e92492.


Identification of CD44 as a surface biomarker for drug resistance by surface proteome signature technology.

Cain JW, Hauptschein RS, Stewart JK, Bagci T, Sahagian GG, Jay DG.

Mol Cancer Res. 2011 May;9(5):637-47. doi: 10.1158/1541-7786.MCR-09-0237. Epub 2011 Feb 25.


Brain metastases of mouse mammary adenocarcinoma is increased by acute stress.

Rozniecki JJ, Sahagian GG, Kempuraj D, Tao K, Jocobson S, Zhang B, Theoharides TC.

Brain Res. 2010 Dec 17;1366:204-10. doi: 10.1016/j.brainres.2010.09.085. Epub 2010 Sep 29.


Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cells.

Hinton A, Sennoune SR, Bond S, Fang M, Reuveni M, Sahagian GG, Jay D, Martinez-Zaguilan R, Forgac M.

J Biol Chem. 2009 Jun 12;284(24):16400-8. doi: 10.1074/jbc.M901201200. Epub 2009 Apr 14.


Imagable 4T1 model for the study of late stage breast cancer.

Tao K, Fang M, Alroy J, Sahagian GG.

BMC Cancer. 2008 Aug 9;8:228. doi: 10.1186/1471-2407-8-228.


Role of N-linked oligosaccharide flexibility in mannose phosphorylation of lysosomal enzyme cathepsin L.

Warner JB, Thalhauser C, Tao K, Sahagian GG.

J Biol Chem. 2002 Nov 1;277(44):41897-905. Epub 2002 Aug 28.


Multiple lysosomal trafficking phenotypes in metastatic mouse mammary tumor cell lines.

Tao K, Li J, Warner J, MacLeod K, Miller FR, Sahagian GG.

Int J Oncol. 2001 Dec;19(6):1333-9.


Lysine-based structure in the proregion of procathepsin L is the recognition site for mannose phosphorylation.

Cuozzo JW, Tao K, Wu QL, Young W, Sahagian GG.

J Biol Chem. 1995 Jun 30;270(26):15611-9.


Lysine is a common determinant for mannose phosphorylation of lysosomal proteins.

Cuozzo JW, Sahagian GG.

J Biol Chem. 1994 May 20;269(20):14490-6.


The proregion of cathepsin L is required for proper folding, stability, and ER exit.

Tao K, Stearns NA, Dong J, Wu QL, Sahagian GG.

Arch Biochem Biophys. 1994 May 15;311(1):19-27.


Comparison of cathepsin L synthesized by normal and transformed cells at the gene, message, protein, and oligosaccharide levels.

Stearns NA, Dong JM, Pan JX, Brenner DA, Sahagian GG.

Arch Biochem Biophys. 1990 Dec;283(2):447-57.


Modulation of the transport of a lysosomal enzyme by PDGF.

Prence EM, Dong JM, Sahagian GG.

J Cell Biol. 1990 Feb;110(2):319-26.


Bovine testicular beta-galactosidase: purification of enzyme fractions that exhibit high affinity for phosphomannosyl receptors.

Distler JJ, Guo JF, Sahagian GG, Jourdian GW.

Anal Biochem. 1989 Nov 1;182(2):432-7.


Transport of surface mannose 6-phosphate receptor to the Golgi complex in cultured human cells.

Jin M, Sahagian GG Jr, Snider MD.

J Biol Chem. 1989 May 5;264(13):7675-80.


Mechanism for selective secretion of a lysosomal protease by transformed mouse fibroblasts.

Dong JM, Prence EM, Sahagian GG.

J Biol Chem. 1989 May 5;264(13):7377-83.


Insulin-like growth factor-II (IGF-II) inhibits both the cellular uptake of beta-galactosidase and the binding of beta-galactosidase to purified IGF-II/mannose 6-phosphate receptor.

Kiess W, Thomas CL, Greenstein LA, Lee L, Sklar MM, Rechler MM, Sahagian GG, Nissley SP.

J Biol Chem. 1989 Mar 15;264(8):4710-4.


Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor.

Kiess W, Blickenstaff GD, Sklar MM, Thomas CL, Nissley SP, Sahagian GG.

J Biol Chem. 1988 Jul 5;263(19):9339-44.

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