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Results: 1 to 20 of 100

1.

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, McCallie D Jr, Szolovits P, Willard HF, Mendelsohn NJ, Temme R, Finkel RS, Yum SW, Medne L, Sunyaev SR, Adzhubey I, Cassa CA, de Bakker PI, Duzkale H, Dworzyński P, Fairbrother W, Francioli L, Funke BH, Giovanni MA, Handsaker RE, Lage K, Lebo MS, Lek M, Leshchiner I, MacArthur DG, McLaughlin HM, Murray MF, Pers TH, Polak PP, Raychaudhuri S, Rehm HL, Soemedi R, Stitziel NO, Vestecka S, Supper J, Gugenmus C, Klocke B, Hahn A, Schubach M, Menzel M, Biskup S, Freisinger P, Deng M, Braun M, Perner S, Smith RJ, Andorf JL, Huang J, Ryckman K, Sheffield VC, Stone EM, Bair T, Black-Ziegelbein EA, Braun TA, Darbro B, DeLuca AP, Kolbe DL, Scheetz TE, Shearer AE, Sompallae R, Wang K, Bassuk AG, Edens E, Mathews K, Moore SA, Shchelochkov OA, Trapane P, Bossler A, Campbell CA, Heusel JW, Kwitek A, Maga T, Panzer K, Wassink T, Van Daele D, Azaiez H, Booth K, Meyer N, Segal MM, Williams MS, Tromp G, White P, Corsmeier D, Fitzgerald-Butt S, Herman G, Lamb-Thrush D, McBride KL, Newsom D, Pierson CR, Rakowsky AT, Maver A, Lovrečić L, Palandačić A, Peterlin B, Torkamani A, Wedell A, Huss M, Alexeyenko A, Lindvall JM, Magnusson M, Nilsson D, Stranneheim H, Taylan F, Gilissen C, Hoischen A, van Bon B, Yntema H, Nelen M, Zhang W, Sager J, Zhang L, Blair K, Kural D, Cariaso M, Lennon GG, Javed A, Agrawal S, Ng PC, Sandhu KS, Krishna S, Veeramachaneni V, Isakov O, Halperin E, Friedman E, Shomron N, Glusman G, Roach JC, Caballero J, Cox HC, Mauldin D, Ament SA, Rowen L, Richards DR, San Lucas FA, Gonzalez-Garay ML, Caskey CT, Bai Y, Huang Y, Fang F, Zhang Y, Wang Z, Barrera J, Garcia-Lobo JM, González-Lamuño D, Llorca J, Rodriguez MC, Varela I, Reese MG, De La Vega FM, Kiruluta E, Cargill M, Hart RK, Sorenson JM, Lyon GJ, Stevenson DA, Bray BE, Moore BM, Eilbeck K, Yandell M, Zhao H, Hou L, Chen X, Yan X, Chen M, Li C, Yang C, Gunel M, Li P, Kong Y, Alexander AC, Albertyn ZI, Boycott KM, Bulman DE, Gordon PM, Innes AM, Knoppers BM, Majewski J, Marshall CR, Parboosingh JS, Sawyer SL, Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM.

Genome Biol. 2014 Mar 25;15(3):R53. doi: 10.1186/gb-2014-15-3-r53.

PMID:
24667040
[PubMed - in process]
Free PMC Article
2.

Fluoxetine- and norfluoxetine-mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19, and CYP3A4.

Sager JE, Lutz JD, Foti RS, Davis C, Kunze KL, Isoherranen N.

Clin Pharmacol Ther. 2014 Jun;95(6):653-62. doi: 10.1038/clpt.2014.50. Epub 2014 Feb 25.

PMID:
24569517
[PubMed - indexed for MEDLINE]
3.

Arcanobacterium pluranimalium leading to a bovine mastitis: species identification by a newly developed pla gene based PCR.

Moser A, Stephan R, Sager J, Corti S, Lehner A.

Schweiz Arch Tierheilkd. 2013 Jun;155(6):373-5. doi: 10.1024/0036-7281/a000473.

PMID:
23732384
[PubMed - in process]
4.

Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactions.

Shirasaka Y, Sager JE, Lutz JD, Davis C, Isoherranen N.

Drug Metab Dispos. 2013 Jul;41(7):1414-24. doi: 10.1124/dmd.113.051722. Epub 2013 Apr 25.

PMID:
23620487
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Developmental stage-specific metabolic and transcriptional activity of Chlamydia trachomatis in an axenic medium.

Omsland A, Sager J, Nair V, Sturdevant DE, Hackstadt T.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19781-5. doi: 10.1073/pnas.1212831109. Epub 2012 Nov 5. Erratum in: Proc Natl Acad Sci U S A. 2013 Jan 20;110(5):1970.

PMID:
23129646
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The zebrafish homologue of the human DYT1 dystonia gene is widely expressed in CNS neurons but non-essential for early motor system development.

Sager JJ, Torres GE, Burton EA.

PLoS One. 2012;7(9):e45175. doi: 10.1371/journal.pone.0045175. Epub 2012 Sep 28.

PMID:
23028827
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.

Milanese C, Sager JJ, Bai Q, Farrell TC, Cannon JR, Greenamyre JT, Burton EA.

J Biol Chem. 2012 Jan 27;287(5):2971-83. doi: 10.1074/jbc.M111.308312. Epub 2011 Nov 29.

PMID:
22128150
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Proteins interacting with monoamine transporters: current state and future challenges.

Sager JJ, Torres GE.

Biochemistry. 2011 Aug 30;50(34):7295-310. doi: 10.1021/bi200405c. Epub 2011 Aug 5. Review.

PMID:
21797260
[PubMed - indexed for MEDLINE]
9.

The trans-Golgi SNARE syntaxin 6 is recruited to the chlamydial inclusion membrane.

Moore ER, Mead DJ, Dooley CA, Sager J, Hackstadt T.

Microbiology. 2011 Mar;157(Pt 3):830-8. doi: 10.1099/mic.0.045856-0. Epub 2010 Nov 25.

PMID:
21109560
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

NOTES for the cardia: antireflux therapy via transluminal access.

Wilhelm D, Meining A, Schneider A, von Delius S, Preissel A, Sager J, Fiolka A, Friess H, Feussner H.

Endoscopy. 2010 Dec;42(12):1085-91. doi: 10.1055/s-0030-1255882. Epub 2010 Oct 22.

PMID:
20972953
[PubMed - indexed for MEDLINE]
11.

Carbon dioxide versus room air for natural orifice transluminal endoscopic surgery (NOTES) and comparison with standard laparoscopic pneumoperitoneum.

von Delius S, Sager J, Feussner H, Wilhelm D, Thies P, Huber W, Schuster T, Schneider A, Schmid RM, Meining A.

Gastrointest Endosc. 2010 Jul;72(1):161-9, 169.e1-2. doi: 10.1016/j.gie.2010.01.013. Epub 2010 Apr 8.

PMID:
20381043
[PubMed - indexed for MEDLINE]
12.

Natural orifice transluminal endoscopic surgery: cardiopulmonary safety of transesophageal mediastinoscopy.

von Delius S, Wilhelm D, Feussner H, Sager J, Becker V, Schuster T, Schneider A, Schmid RM, Meining A.

Endoscopy. 2010 May;42(5):405-12. doi: 10.1055/s-0029-1243948. Epub 2010 Mar 4.

PMID:
20205072
[PubMed - indexed for MEDLINE]
13.

Transgenic zebrafish models of neurodegenerative diseases.

Sager JJ, Bai Q, Burton EA.

Brain Struct Funct. 2010 Mar;214(2-3):285-302. doi: 10.1007/s00429-009-0237-1. Epub 2010 Feb 17. Review.

PMID:
20162303
[PubMed - indexed for MEDLINE]
14.

A phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignancies.

Camidge DR, Herbst RS, Gordon MS, Eckhardt SG, Kurzrock R, Durbin B, Ing J, Tohnya TM, Sager J, Ashkenazi A, Bray G, Mendelson D.

Clin Cancer Res. 2010 Feb 15;16(4):1256-63. doi: 10.1158/1078-0432.CCR-09-1267. Epub 2010 Feb 9.

PMID:
20145186
[PubMed - indexed for MEDLINE]
Free Article
15.

Pulmonary complications of cirrhosis.

Singh C, Sager JS.

Med Clin North Am. 2009 Jul;93(4):871-83, viii. doi: 10.1016/j.mcna.2009.03.006. Review.

PMID:
19577119
[PubMed - indexed for MEDLINE]
16.

Wide variation in clinicians' assessment of New York Heart Association/World Health Organization functional class in patients with pulmonary arterial hypertension.

Taichman DB, McGoon MD, Harhay MO, Archer-Chicko C, Sager JS, Murugappan M, Chakinali MM, Palevsky HI, Gallop R.

Mayo Clin Proc. 2009 Jul;84(7):586-92. doi: 10.1016/S0025-6196(11)60747-7.

PMID:
19567712
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The relationship between health literacy and knowledge improvement after a multimedia type 2 diabetes education program.

Kandula NR, Nsiah-Kumi PA, Makoul G, Sager J, Zei CP, Glass S, Stephens Q, Baker DW.

Patient Educ Couns. 2009 Jun;75(3):321-7. doi: 10.1016/j.pec.2009.04.001. Epub 2009 Apr 22.

PMID:
19395223
[PubMed - indexed for MEDLINE]
18.

Outcomes using extracorporeal life support for adult respiratory failure due to status asthmaticus.

Mikkelsen ME, Woo YJ, Sager JS, Fuchs BD, Christie JD.

ASAIO J. 2009 Jan-Feb;55(1):47-52. doi: 10.1097/MAT.0b013e3181901ea5.

PMID:
19092662
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.

Smith ED, Kaeberlein TL, Lydum BT, Sager J, Welton KL, Kennedy BK, Kaeberlein M.

BMC Dev Biol. 2008 May 5;8:49. doi: 10.1186/1471-213X-8-49.

PMID:
18457595
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Will targeted therapy hold its promise? An evidence-based review.

Murdoch D, Sager J.

Curr Opin Oncol. 2008 Jan;20(1):104-11. Review.

PMID:
18043264
[PubMed - indexed for MEDLINE]

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