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Results: 11

1.

Targeting dynamic pockets of HIV-1 protease by structure-based computational screening for allosteric inhibitors.

Kunze J, Todoroff N, Schneider P, Rodrigues T, Geppert T, Reisen F, Schreuder H, Saas J, Hessler G, Baringhaus KH, Schneider G.

J Chem Inf Model. 2014 Mar 24;54(3):987-91. doi: 10.1021/ci400712h. Epub 2014 Feb 14.

PMID:
24528206
[PubMed - in process]
2.

IL-1beta, but not BMP-7 leads to a dramatic change in the gene expression pattern of human adult articular chondrocytes--portraying the gene expression pattern in two donors.

Saas J, Haag J, Rueger D, Chubinskaya S, Sohler F, Zimmer R, Bartnik E, Aigner T.

Cytokine. 2006 Oct;36(1-2):90-9. Epub 2006 Dec 11.

PMID:
17161615
[PubMed - indexed for MEDLINE]
3.

Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis.

Aigner T, Fundel K, Saas J, Gebhard PM, Haag J, Weiss T, Zien A, Obermayr F, Zimmer R, Bartnik E.

Arthritis Rheum. 2006 Nov;54(11):3533-44.

PMID:
17075858
[PubMed - indexed for MEDLINE]
Free Article
4.

The human chondrosarcoma HCS-2/8 cell line is responsive to BMP-7, but not to IL-1beta.

Saas J, Gebauer M, Jacobi C, Haag J, Takigawa M, Aigner T.

Front Biosci. 2005 May 1;10:2027-35.

PMID:
15970475
[PubMed - indexed for MEDLINE]
5.

Comparison of the chondrosarcoma cell line SW1353 with primary human adult articular chondrocytes with regard to their gene expression profile and reactivity to IL-1beta.

Gebauer M, Saas J, Sohler F, Haag J, Söder S, Pieper M, Bartnik E, Beninga J, Zimmer R, Aigner T.

Osteoarthritis Cartilage. 2005 Aug;13(8):697-708.

PMID:
15950496
[PubMed - indexed for MEDLINE]
Free Article
6.

Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage.

Gebauer M, Saas J, Haag J, Dietz U, Takigawa M, Bartnik E, Aigner T.

Arthritis Res Ther. 2005;7(2):R274-84. Epub 2005 Jan 11.

PMID:
15743474
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Molecular phenotyping of HCS-2/8 cells as an in vitro model of human chondrocytes.

Saas J, Lindauer K, Bau B, Takigawa M, Aigner T.

Osteoarthritis Cartilage. 2004 Nov;12(11):924-34.

PMID:
15501409
[PubMed - indexed for MEDLINE]
Free Article
8.

Analysis of differential gene expression in healthy and osteoarthritic cartilage and isolated chondrocytes by microarray analysis.

Aigner T, Saas J, Zien A, Zimmer R, Gebhard PM, Knorr T.

Methods Mol Med. 2004;100:109-28.

PMID:
15280592
[PubMed - indexed for MEDLINE]
9.

Procyclic Trypanosoma brucei do not use Krebs cycle activity for energy generation.

van Weelden SW, Fast B, Vogt A, van der Meer P, Saas J, van Hellemond JJ, Tielens AG, Boshart M.

J Biol Chem. 2003 Apr 11;278(15):12854-63. Epub 2003 Jan 31.

PMID:
12562769
[PubMed - indexed for MEDLINE]
Free Article
10.

A developmentally regulated aconitase related to iron-regulatory protein-1 is localized in the cytoplasm and in the mitochondrion of Trypanosoma brucei.

Saas J, Ziegelbauer K, von Haeseler A, Fast B, Boshart M.

J Biol Chem. 2000 Jan 28;275(4):2745-55.

PMID:
10644738
[PubMed - indexed for MEDLINE]
Free Article
11.

An in vitro-differentiated human cell line as a model system to study the interaction of Neisseria gonorrhoeae with phagocytic cells.

Hauck CR, Lorenzen D, Saas J, Meyer TF.

Infect Immun. 1997 May;65(5):1863-9.

PMID:
9125573
[PubMed - indexed for MEDLINE]
Free PMC Article

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