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Items: 1 to 20 of 145

1.

Constant B-cell lymphocytosis since early age in a patient with CARD11 mutation: A 20-year follow-up.

Outinen T, Syrjänen J, Rounioja S, Saarela J, Kaustio M, Helminen M.

Clin Immunol. 2016 Feb 6. pii: S1521-6616(16)30018-3. doi: 10.1016/j.clim.2016.02.002. [Epub ahead of print] No abstract available.

PMID:
26861442
2.

Precision Cancer Medicine in the Acoustic Dispensing Era: Ex Vivo Primary Cell Drug Sensitivity Testing.

Kulesskiy E, Saarela J, Turunen L, Wennerberg K.

J Lab Autom. 2016 Feb;21(1):27-36. doi: 10.1177/2211068215618869. Epub 2015 Dec 2.

PMID:
26721820
3.

Association study of MMP8 gene in osteoarthritis.

Näkki A, Rodriguez-Fontenla C, Gonzalez A, Harilainen A, Leino-Arjas P, Heliövaara M, Eriksson JG, Tallroth K, Videman T, Kaprio J, Saarela J, Kujala UM.

Connect Tissue Res. 2015 Nov 17:1-9. [Epub ahead of print]

PMID:
26577236
4.

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.

Pokharel YR, Saarela J, Szwajda A, Rupp C, Rokka A, Lal Kumar Karna S, Teittinen K, Corthals G, Kallioniemi O, Wennerberg K, Aittokallio T, Westermarck J.

Mol Cell Proteomics. 2015 Dec;14(12):3274-83. doi: 10.1074/mcp.M115.050773. Epub 2015 Oct 23.

PMID:
26499835
5.

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TM, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Lar Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J; International IBD Genetics Consortium (IIBDGC), Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CC, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G; International Multiple Sclerosis Genetics Consortium.

Nat Genet. 2015 Oct;47(10):1107-13. doi: 10.1038/ng.3395. Epub 2015 Sep 7.

PMID:
26343388
6.

New vascular plant records for the Canadian Arctic Archipelago.

Gillespie LJ, Saarela JM, Sokoloff PC, Bull RD.

PhytoKeys. 2015 Jun 25;(52):23-79. doi: 10.3897/phytokeys.52.8721. eCollection 2015.

7.

Stimulating translational research: several European life science institutions put their heads together.

Bentires-Alj M, Rajan A, van Harten W, van Luenen HG, Kubicek S, Andersen JB, Saarela J, Cook SJ, Van Minnebruggen G, Roman-Roman S, Maurer C, Erler JT, Bertero MG.

Trends Mol Med. 2015 Sep;21(9):525-7. doi: 10.1016/j.molmed.2015.07.002. Epub 2015 Aug 5.

PMID:
26254816
8.

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.

Szwajda A, Gautam P, Karhinen L, Jha SK, Saarela J, Shakyawar S, Turunen L, Yadav B, Tang J, Wennerberg K, Aittokallio T.

Chem Biol. 2015 Aug 20;22(8):1144-55. doi: 10.1016/j.chembiol.2015.06.021. Epub 2015 Jul 23.

PMID:
26211361
9.

Dermatologic Features of ADA2 Deficiency in Cutaneous Polyarteritis Nodosa.

Gonzalez Santiago TM, Zavialov A, Saarela J, Seppanen M, Reed AM, Abraham RS, Gibson LE.

JAMA Dermatol. 2015 Nov 1;151(11):1230-4. doi: 10.1001/jamadermatol.2015.1635.

PMID:
26131734
10.

Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections.

Dobbs K, Domínguez Conde C, Zhang SY, Parolini S, Audry M, Chou J, Haapaniemi E, Keles S, Bilic I, Okada S, Massaad MJ, Rounioja S, Alwahadneh AM, Serwas NK, Capuder K, Çiftçi E, Felgentreff K, Ohsumi TK, Pedergnana V, Boisson B, Haskoloğlu Ş, Ensari A, Schuster M, Moretta A, Itan Y, Patrizi O, Rozenberg F, Lebon P, Saarela J, Knip M, Petrovski S, Goldstein DB, Parrott RE, Savas B, Schambach A, Tabellini G, Bock C, Chatila TA, Comeau AM, Geha RS, Abel L, Buckley RH, İkincioğulları A, Al-Herz W, Helminen M, Doğu F, Casanova JL, Boztuğ K, Notarangelo LD.

N Engl J Med. 2015 Jun 18;372(25):2409-22. doi: 10.1056/NEJMoa1413462.

11.

Plastid phylogenomics of the cool-season grass subfamily: clarification of relationships among early-diverging tribes.

Saarela JM, Wysocki WP, Barrett CF, Soreng RJ, Davis JI, Clark LG, Kelchner SA, Pires JC, Edger PP, Mayfield DR, Duvall MR.

AoB Plants. 2015 May 4;7. pii: plv046. doi: 10.1093/aobpla/plv046.

12.

Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.

Hiltunen TP, Donner KM, Sarin AP, Saarela J, Ripatti S, Chapman AB, Gums JG, Gong Y, Cooper-DeHoff RM, Frau F, Glorioso V, Zaninello R, Salvi E, Glorioso N, Boerwinkle E, Turner ST, Johnson JA, Kontula KK.

J Am Heart Assoc. 2015 Jan 26;4(1):e001521. doi: 10.1161/JAHA.115.001778.

13.

Testing the anniversary reaction: causal effects of bereavement in a nationwide follow-up study from Sweden.

Rostila M, Saarela J, Kawachi I, Hjern A.

Eur J Epidemiol. 2015 Mar;30(3):239-47. doi: 10.1007/s10654-015-9989-5. Epub 2015 Jan 17.

PMID:
25595319
14.

Suppression of BRCA1 sensitizes cells to proteasome inhibitors.

Gu Y, Bouwman P, Greco D, Saarela J, Yadav B, Jonkers J, Kuznetsov SG.

Cell Death Dis. 2014 Dec 18;5:e1580. doi: 10.1038/cddis.2014.537.

15.

Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.

van Adrichem AJ, Fagerholm A, Turunen L, Lehto A, Saarela J, Koskinen A, Repasky GA, Wennerberg K.

Comb Chem High Throughput Screen. 2015;18(1):3-17.

16.

Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3.

Haapaniemi EM, Kaustio M, Rajala HL, van Adrichem AJ, Kainulainen L, Glumoff V, Doffinger R, Kuusanmäki H, Heiskanen-Kosma T, Trotta L, Chiang S, Kulmala P, Eldfors S, Katainen R, Siitonen S, Karjalainen-Lindsberg ML, Kovanen PE, Otonkoski T, Porkka K, Heiskanen K, Hänninen A, Bryceson YT, Uusitalo-Seppälä R, Saarela J, Seppänen M, Mustjoki S, Kere J.

Blood. 2015 Jan 22;125(4):639-48. doi: 10.1182/blood-2014-04-570101. Epub 2014 Oct 27.

17.

Genetic background of extreme violent behavior.

Tiihonen J, Rautiainen MR, Ollila HM, Repo-Tiihonen E, Virkkunen M, Palotie A, Pietiläinen O, Kristiansson K, Joukamaa M, Lauerma H, Saarela J, Tyni S, Vartiainen H, Paananen J, Goldman D, Paunio T.

Mol Psychiatry. 2015 Jun;20(6):786-92. doi: 10.1038/mp.2014.130. Epub 2014 Oct 28.

PMID:
25349169
18.

Myostatin/activin blocking combined with exercise reconditions skeletal muscle expression profile of mdx mice.

Kainulainen H, Papaioannou KG, Silvennoinen M, Autio R, Saarela J, Oliveira BM, Nyqvist M, Pasternack A, 't Hoen PA, Kujala UM, Ritvos O, Hulmi JJ.

Mol Cell Endocrinol. 2015 Jan 5;399:131-42. doi: 10.1016/j.mce.2014.10.001. Epub 2014 Oct 7.

PMID:
25304272
19.

Functional variations modulating PRKCA expression and alternative splicing predispose to multiple sclerosis.

Paraboschi EM, Rimoldi V, Soldà G, Tabaglio T, Dall'Osso C, Saba E, Vigliano M, Salviati A, Leone M, Benedetti MD, Fornasari D, Saarela J, De Jager PL, Patsopoulos NA, D'Alfonso S, Gemmati D, Duga S, Asselta R.

Hum Mol Genet. 2014 Dec 20;23(25):6746-61. doi: 10.1093/hmg/ddu392. Epub 2014 Jul 30.

20.

Birth order and suicide in adulthood: evidence from Swedish population data.

Rostila M, Saarela J, Kawachi I.

Am J Epidemiol. 2014 Jun 15;179(12):1450-7. doi: 10.1093/aje/kwu090. Epub 2014 May 13.

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