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Results: 1 to 20 of 27


Editorial: Role of lipids in virus assembly.

Saad JS, Muriaux DM.

Front Microbiol. 2015 May 5;6:410. doi: 10.3389/fmicb.2015.00410. eCollection 2015. No abstract available.


Targeting the Early Step of Building Block Organization in Viral Capsid Assembly.

Lampel A, Bram Y, Ezer A, Shaltiel-Kario R, Saad JS, Bacharach E, Gazit E.

ACS Chem Biol. 2015 Aug 21;10(8):1785-90. doi: 10.1021/acschembio.5b00347. Epub 2015 May 29.


Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane.

Vlach J, Saad JS.

Front Microbiol. 2015 Mar 20;6:232. doi: 10.3389/fmicb.2015.00232. eCollection 2015.


HIV: a vicTIM.

Vlach J, Saad JS.

Trends Microbiol. 2014 Nov;22(11):603-4. doi: 10.1016/j.tim.2014.09.008. Epub 2014 Oct 16.


Solution structure of calmodulin bound to the binding domain of the HIV-1 matrix protein.

Vlach J, Samal AB, Saad JS.

J Biol Chem. 2014 Mar 21;289(12):8697-705. doi: 10.1074/jbc.M113.543694. Epub 2014 Feb 5.


Spectrum of pneumococcal serotype 11A variants results from incomplete loss of capsule O-acetylation.

Calix JJ, Brady AM, Du VY, Saad JS, Nahm MH.

J Clin Microbiol. 2014 Mar;52(3):758-65. doi: 10.1128/JCM.02695-13. Epub 2013 Dec 18.


Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units.

Oliver MB, van der Linden MP, K√ľntzel SA, Saad JS, Nahm MH.

J Biol Chem. 2013 Sep 6;288(36):25976-85. doi: 10.1074/jbc.M113.480152. Epub 2013 Jul 29.


Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin.

Fernandez TF, Samal AB, Bedwell GJ, Chen Y, Saad JS.

J Biol Chem. 2013 Jul 26;288(30):21898-908. doi: 10.1074/jbc.M113.471821. Epub 2013 Jun 11.


Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers.

Vlach J, Saad JS.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3525-30. doi: 10.1073/pnas.1216655110. Epub 2013 Feb 11.


Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly.

Ghanam RH, Samal AB, Fernandez TF, Saad JS.

Front Microbiol. 2012 Feb 17;3:55. doi: 10.3389/fmicb.2012.00055. eCollection 2012.


The Staphylococcus aureus pathogenicity island 1 protein gp6 functions as an internal scaffold during capsid size determination.

Dearborn AD, Spilman MS, Damle PK, Chang JR, Monroe EB, Saad JS, Christie GE, Dokland T.

J Mol Biol. 2011 Sep 30;412(4):710-22. doi: 10.1016/j.jmb.2011.07.036. Epub 2011 Jul 29.


Single-stranded oligonucleotide adducts formed by Pt complexes favoring left-handed base canting: steric effect of flanking residues and relevance to DNA adducts formed by Pt anticancer drugs.

Saad JS, Marzilli PA, Intini FP, Natile G, Marzilli LG.

Inorg Chem. 2011 Sep 5;50(17):8608-20. doi: 10.1021/ic2011716. Epub 2011 Aug 5.


NMR, biophysical, and biochemical studies reveal the minimal Calmodulin binding domain of the HIV-1 matrix protein.

Samal AB, Ghanam RH, Fernandez TF, Monroe EB, Saad JS.

J Biol Chem. 2011 Sep 23;286(38):33533-43. doi: 10.1074/jbc.M111.273623. Epub 2011 Jul 28.


NMR studies of models having the Pt(d(GpG)) 17-membered macrocyclic ring formed in DNA by platinum anticancer drugs: Pt complexes with bulky chiral diamine ligands.

Saad JS, Benedetti M, Natile G, Marzilli LG.

Inorg Chem. 2011 May 16;50(10):4559-71. doi: 10.1021/ic200259s. Epub 2011 Apr 21.


Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure.

Ghanam RH, Fernandez TF, Fledderman EL, Saad JS.

J Biol Chem. 2010 Dec 31;285(53):41911-20. doi: 10.1074/jbc.M110.179093. Epub 2010 Oct 18.


Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH.

Fledderman EL, Fujii K, Ghanam RH, Waki K, Prevelige PE, Freed EO, Saad JS.

Biochemistry. 2010 Nov 9;49(44):9551-62. doi: 10.1021/bi101245j.


Basic coordination chemistry relevant to DNA adducts formed by the cisplatin anticancer drug. NMR studies on compounds with sterically crowded chiral ligands.

Saad JS, Benedetti M, Natile G, Marzilli LG.

Inorg Chem. 2010 Jun 21;49(12):5573-83. doi: 10.1021/ic100494f.


Reverse micelle encapsulation of membrane-anchored proteins for solution NMR studies.

Valentine KG, Peterson RW, Saad JS, Summers MF, Xu X, Ames JB, Wand AJ.

Structure. 2010 Jan 13;18(1):9-16. doi: 10.1016/j.str.2009.11.010.

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