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See Gene information for ptpn2 stat1

ptpn2 in Homo sapiens (2)Mus musculus (2)Rattus norvegicus (2)All 184 Gene records

stat1 in Homo sapiens (2)Mus musculus (2)Rattus norvegicus (2)All 179 Gene records

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Items: 16


A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2).

Duval R, Bui LC, Berthelet J, Dairou J, Mathieu C, Guidez F, Dupret JM, Cools J, Chomienne C, Rodrigues-Lima F.

Sci Rep. 2015 Jun 4;5:10750. doi: 10.1038/srep10750.


Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2.

Gurzov EN, Tran M, Fernandez-Rojo MA, Merry TL, Zhang X, Xu Y, Fukushima A, Waters MJ, Watt MJ, Andrikopoulos S, Neel BG, Tiganis T.

Cell Metab. 2014 Jul 1;20(1):85-102. doi: 10.1016/j.cmet.2014.05.011. Epub 2014 Jun 19.


Network analysis identifies protein clusters of functional importance in juvenile idiopathic arthritis.

Stevens A, Meyer S, Hanson D, Clayton P, Donn RP.

Arthritis Res Ther. 2014 May 8;16(3):R109. doi: 10.1186/ar4559.


High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage.

Merry TL, Tran M, Stathopoulos M, Wiede F, Fam BC, Dodd GT, Clarke I, Watt MJ, Andrikopoulos S, Tiganis T.

Antioxid Redox Signal. 2014 May 10;20(14):2114-29. doi: 10.1089/ars.2013.5428. Epub 2014 Mar 11.


Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis.

Morón B, Spalinger M, Kasper S, Atrott K, Frey-Wagner I, Fried M, McCole DF, Rogler G, Scharl M.

PLoS One. 2013 Sep 9;8(9):e73703. doi: 10.1371/journal.pone.0073703. eCollection 2013.


The role of TC-PTP (PTPN2) in modulating sensitivity to imatinib and interferon-α in CML cell line, KT-1 cells.

Nishiyama-Fujita Y, Shimizu T, Sagawa M, Uchida H, Kizaki M.

Leuk Res. 2013 Sep;37(9):1150-5. doi: 10.1016/j.leukres.2013.05.008. Epub 2013 Jun 4.


PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.

Santin I, Moore F, Colli ML, Gurzov EN, Marselli L, Marchetti P, Eizirik DL.

Diabetes. 2011 Dec;60(12):3279-88. doi: 10.2337/db11-0758. Epub 2011 Oct 7.


Increased susceptibility to dextran sulfate sodium induced colitis in the T cell protein tyrosine phosphatase heterozygous mouse.

Hassan SW, Doody KM, Hardy S, Uetani N, Cournoyer D, Tremblay ML.

PLoS One. 2010 Jan 25;5(1):e8868. doi: 10.1371/journal.pone.0008868.


Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2.

Scharl M, Paul G, Weber A, Jung BC, Docherty MJ, Hausmann M, Rogler G, Barrett KE, McCole DF.

Gastroenterology. 2009 Dec;137(6):2030-2040.e5. doi: 10.1053/j.gastro.2009.07.078. Epub 2009 Oct 8.


PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.

Moore F, Colli ML, Cnop M, Esteve MI, Cardozo AK, Cunha DA, Bugliani M, Marchetti P, Eizirik DL.

Diabetes. 2009 Jun;58(6):1283-91. doi: 10.2337/db08-1510. Epub 2009 Mar 31.


TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}.

Bourdeau A, Dubé N, Heinonen KM, Théberge JF, Doody KM, Tremblay ML.

Blood. 2007 May 15;109(10):4220-8. Epub 2007 Jan 18.


Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells.

Sakamoto S, Qin J, Navarro A, Gamero A, Potla R, Yi T, Zhu W, Baker DP, Feldman G, Larner AC.

J Biol Chem. 2004 Jan 30;279(5):3245-53. Epub 2003 Nov 4.


Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase.

Zhu W, Mustelin T, David M.

J Biol Chem. 2002 Sep 27;277(39):35787-90. Epub 2002 Aug 8.


Identification of a nuclear Stat1 protein tyrosine phosphatase.

ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, Zhu W, Tremblay M, David M, Shuai K.

Mol Cell Biol. 2002 Aug;22(16):5662-8.


The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.

Simoncic PD, Lee-Loy A, Barber DL, Tremblay ML, McGlade CJ.

Curr Biol. 2002 Mar 19;12(6):446-53.

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