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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 4
1999 3
2000 1
2002 2
2003 1
2004 3
2005 5
2007 1
2008 2
2009 3
2010 3
2011 5
2012 6
2013 2
2014 3
2015 5
2016 7
2017 7
2018 7
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2020 16
2021 15
2022 17
2023 15
2024 2

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125 results

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Page 1
Long non-coding RNA SOX21-AS1: A potential tumor oncogene in human cancers.
Lu Z, Xu J, Cao B, Jin C. Lu Z, et al. Pathol Res Pract. 2023 Sep;249:154774. doi: 10.1016/j.prp.2023.154774. Epub 2023 Aug 19. Pathol Res Pract. 2023. PMID: 37633003 Review.
SOX21-AS1 is markedly associated with poor prognosis and low survival of patients, proposing that it may be a prognostic and diagnostic biomarker in cancer. Overexpression of SOX21-AS1 is related to various cancer-related pathways, like epithelial mesenchymal transi …
SOX21-AS1 is markedly associated with poor prognosis and low survival of patients, proposing that it may be a prognostic and diagnost …
SOX2 and SOX21 in Lung Epithelial Differentiation and Repair.
Eenjes E, Tibboel D, Wijnen RMH, Schnater JM, Rottier RJ. Eenjes E, et al. Int J Mol Sci. 2022 Oct 27;23(21):13064. doi: 10.3390/ijms232113064. Int J Mol Sci. 2022. PMID: 36361852 Free PMC article. Review.
This process is controlled by specific transcription factors, such as the SRY-related HMG-box genes SOX2 and SOX21, that are activated or repressed through intrinsic and extrinsic signals. ...In this concise review, we describe different intrinsic and extrinsic cellular pr …
This process is controlled by specific transcription factors, such as the SRY-related HMG-box genes SOX2 and SOX21, that are activate …
LncRNA SOX21-AS1 accelerates endometrial carcinoma progression through the miR-7-5p/RAF1 pathway.
Sun M, Chen D, Chen Y, Wu Y. Sun M, et al. World J Surg Oncol. 2023 Jul 22;21(1):217. doi: 10.1186/s12957-023-03114-6. World J Surg Oncol. 2023. PMID: 37481582 Free PMC article. Retracted.
However, the mechanism of SOX21-AS1 in EC remains unclear. Our study is intended to probe the mechanisms of SOX21-AS1 on EC progression. ...Functionally, silencing of RAF1 reversed the functions of miR-7-5p inhibitor in the proliferation, invasion, and apoptosis of …
However, the mechanism of SOX21-AS1 in EC remains unclear. Our study is intended to probe the mechanisms of SOX21-AS1 on EC pr …
SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways.
Eenjes E, Buscop-van Kempen M, Boerema-de Munck A, Edel GG, Benthem F, de Kreij-de Bruin L, Schnater M, Tibboel D, Collins J, Rottier RJ. Eenjes E, et al. Elife. 2021 Jul 21;10:e57325. doi: 10.7554/eLife.57325. Elife. 2021. PMID: 34286693 Free PMC article.
Airway progenitor cells in this SOX2+/SOX21+ zone show differentiation to basal cells, specifying cells for the extrapulmonary airways. ...Additionally, in the adult tracheal epithelium, SOX21 inhibits basal to ciliated cell differentiation. This suppressing functio …
Airway progenitor cells in this SOX2+/SOX21+ zone show differentiation to basal cells, specifying cells for the extrapulmonary airway …
Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ.
Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S. Saito K, et al. iScience. 2020 Jul 24;23(7):101329. doi: 10.1016/j.isci.2020.101329. Epub 2020 Jun 30. iScience. 2020. PMID: 32674056 Free PMC article.
The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteoporosis, and ectop …
The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of …
SOX21-AS1 is associated with clinical stage and regulates cell proliferation in nephroblastoma.
Zhang J, Hou T, Qi X, Wang J, Sun X. Zhang J, et al. Biosci Rep. 2019 May 17;39(5):BSR20190602. doi: 10.1042/BSR20190602. Print 2019 May 31. Biosci Rep. 2019. PMID: 30992391 Free PMC article.
LncRNA SOX21 antisense RNA 1 (SOX21-AS1) dysregulated in many types of human cancer, and functioned as tumor suppressor or promoter depending on tumor types. However, there was no report about the role of SOX21-AS1 in nephroblastoma. In the present study, we …
LncRNA SOX21 antisense RNA 1 (SOX21-AS1) dysregulated in many types of human cancer, and functioned as tumor suppressor or pro …
SOX21-AS1 modulates neuronal injury of MMP(+)-treated SH-SY5Y cells via targeting miR-7-5p and inhibiting IRS2.
Xie Y, Zhang S, Lv Z, Long T, Luo Y, Li Z. Xie Y, et al. Neurosci Lett. 2021 Feb 16;746:135602. doi: 10.1016/j.neulet.2020.135602. Epub 2021 Jan 6. Neurosci Lett. 2021. PMID: 33421490
In addition, SOX21-AS1 depletion weakened the cell injury induced by MMP(+). Moreover, SOX21-AS1 knockdown decreased Reactive Oxygen Species (ROS) generation and levels of TNF-alpha, IL-1beta and IL-6, but increased SOD activity. However, SOX21-AS1 up-regulat …
In addition, SOX21-AS1 depletion weakened the cell injury induced by MMP(+). Moreover, SOX21-AS1 knockdown decreased Reactive …
Downregulation of SOX21-AS1 Alleviated Cisplatin Resistance in Cervical Cancer Through Epithelial-Mesenchymal Transition Inhibition.
Tian J, Li Z, Jiang Y, Gu W, Kong E, Hao Q, Kong B, Sun L. Tian J, et al. Rejuvenation Res. 2022 Oct;25(5):243-252. doi: 10.1089/rej.2022.0009. Epub 2022 Oct 12. Rejuvenation Res. 2022. PMID: 36039935
Nevertheless, drug resistance in cancer patients poses a major threat to efficacy of treatment. To explore the underlying modulatory mechanism of SOX21-AS1 in cisplatin resistance in CC cell and mice models, Gepia database was referred for SOX21-AS1 expression in ca …
Nevertheless, drug resistance in cancer patients poses a major threat to efficacy of treatment. To explore the underlying modulatory mechani …
LncRNA SOX21-AS1 Promotes the Growth and Invasiveness of Osteosarcoma Cells Through miR-7-5p/IRS2 Regulatory Network.
Chen H, Chen J. Chen H, et al. Arch Med Res. 2021 Apr;52(3):294-303. doi: 10.1016/j.arcmed.2020.11.007. Epub 2020 Dec 17. Arch Med Res. 2021. PMID: 33341286
SOX21-AS1 competed with IRS2 in binding to miR-7-5p, which formulated the ceRNA signaling in OS. SOX21-AS1 could negatively regulate miR-7-5p expression. Rescue experiments certified that the enhancement of IRS2 would neutralize the inhibition of SOX21-AS1 de …
SOX21-AS1 competed with IRS2 in binding to miR-7-5p, which formulated the ceRNA signaling in OS. SOX21-AS1 could negatively re …
Sox21 is a repressor of neuronal differentiation and is antagonized by YB-1.
Ohba H, Chiyoda T, Endo E, Yano M, Hayakawa Y, Sakaguchi M, Darnell RB, Okano HJ, Okano H. Ohba H, et al. Neurosci Lett. 2004 Apr 1;358(3):157-60. doi: 10.1016/j.neulet.2004.01.026. Neurosci Lett. 2004. PMID: 15039105
Overexpression of Sox21 results in a substantial repression of NGF-induced neurite outgrowth in PC12 cells. Further, we biochemically identified a Sox21-associating protein, Y-box binding protein 1 which not only binds to Sox21 but also partially restores NGF …
Overexpression of Sox21 results in a substantial repression of NGF-induced neurite outgrowth in PC12 cells. Further, we biochemically …
125 results