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125 results

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Page 1
S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1alpha.
Su Y, Xu C, Sun Z, Liang Y, Li G, Tong T, Chen J. Su Y, et al. Aging (Albany NY). 2019 Jan 23;11(2):549-572. doi: 10.18632/aging.101760. Aging (Albany NY). 2019. PMID: 30670674 Free PMC article.
Here, we show that S100A13 is up-regulated in various types of cellular senescence. S100A13 overexpression increases cell surface-associated IL-1alpha level, NF-kappaB activity and subsequent multiple SASP genes induction, whereas S100A13 knockdown has an opp …
Here, we show that S100A13 is up-regulated in various types of cellular senescence. S100A13 overexpression increases cell surf …
The association between S100A13 and HMGA1 in the modulation of thyroid cancer proliferation and invasion.
Zhong J, Liu C, Chen YJ, Zhang QH, Yang J, Kang X, Chen SR, Wen GB, Zu XY, Cao RX. Zhong J, et al. J Transl Med. 2016 Mar 23;14:80. doi: 10.1186/s12967-016-0824-x. J Transl Med. 2016. PMID: 27008379 Free PMC article.
However, the correlation between S100A13 and HMGA1 during cancer progression is not yet well understood. ...Those results would provide an essential insight into the effect of S100A13 on carcinogenesis of thyroid tumor, rending S100A13 to be potential biologi …
However, the correlation between S100A13 and HMGA1 during cancer progression is not yet well understood. ...Those results would provi …
S100A13 is a new angiogenic marker in human melanoma.
Massi D, Landriscina M, Piscazzi A, Cosci E, Kirov A, Paglierani M, Di Serio C, Mourmouras V, Fumagalli S, Biagioli M, Prudovsky I, Miracco C, Santucci M, Marchionni N, Tarantini F. Massi D, et al. Mod Pathol. 2010 Jun;23(6):804-13. doi: 10.1038/modpathol.2010.54. Epub 2010 Mar 5. Mod Pathol. 2010. PMID: 20208480 Free PMC article.
Quantification of S100A13 mRNA was achieved by real-time PCR. We found that S100A13 was expressed in melanocytic lesions; compared with benign nevi, S100A13 protein expression was significantly upregulated in melanomas (P=0.024), in which it correlated positi …
Quantification of S100A13 mRNA was achieved by real-time PCR. We found that S100A13 was expressed in melanocytic lesions; comp …
S100A13, a new marker of angiogenesis in human astrocytic gliomas.
Landriscina M, Schinzari G, Di Leonardo G, Quirino M, Cassano A, D'Argento E, Lauriola L, Scerrati M, Prudovsky I, Barone C. Landriscina M, et al. J Neurooncol. 2006 Dec;80(3):251-9. doi: 10.1007/s11060-006-9189-y. Epub 2006 Jun 14. J Neurooncol. 2006. PMID: 16773219
We investigated the expression of S100A13 in human astrocytic gliomas in relation to tumour grading and vascularization. ...Moreover, both S100A13 and VEGF-A expression significantly correlated with microvessel density and tumour grading. ...
We investigated the expression of S100A13 in human astrocytic gliomas in relation to tumour grading and vascularization. ...Moreover, …
S100A13. Biochemical characterization and subcellular localization in different cell lines.
Ridinger K, Schäfer BW, Durussel I, Cox JA, Heizmann CW. Ridinger K, et al. J Biol Chem. 2000 Mar 24;275(12):8686-94. doi: 10.1074/jbc.275.12.8686. J Biol Chem. 2000. PMID: 10722710 Free article.
Here, we report for the first time the purification and characterization of human recombinant S100A13. Flow dialysis revealed that the homodimeric S100A13 binds four Ca(2+) in two sets of binding sites, both displaying positive cooperativity but of very different af …
Here, we report for the first time the purification and characterization of human recombinant S100A13. Flow dialysis revealed that th …
S100A13 participates in the release of fibroblast growth factor 1 in response to heat shock in vitro.
Landriscina M, Soldi R, Bagalá C, Micucci I, Bellum S, Tarantini F, Prudovsky I, Maciag T. Landriscina M, et al. J Biol Chem. 2001 Jun 22;276(25):22544-52. doi: 10.1074/jbc.M100546200. Epub 2001 Apr 16. J Biol Chem. 2001. PMID: 11410600 Free article.
We report that while expression of S100A13 in NIH 3T3 cells results in the constitutive release of S100A13 into the extracellular compartment at 37 degrees C, co-expression of S100A13 with FGF1 represses the constitutive release of S100A13 and enables …
We report that while expression of S100A13 in NIH 3T3 cells results in the constitutive release of S100A13 into the extracellu …
FGF-1 and S100A13 possibly contribute to angiogenesis in endometriosis.
Hayrabedyan S, Kyurkchiev S, Kehayov I. Hayrabedyan S, et al. J Reprod Immunol. 2005 Oct;67(1-2):87-101. doi: 10.1016/j.jri.2005.07.001. J Reprod Immunol. 2005. PMID: 16165218 Review.
Its signaling pathway of hypoxic activation is tightly interconnected with that of VEGF, and also some of the FGFs. FGF-1 and S100A13 are members of two distinct families of proteins -- the FGFs, growth and angiogenic factors, and that of the S100 proteins, -- Ca(2+)-bindi …
Its signaling pathway of hypoxic activation is tightly interconnected with that of VEGF, and also some of the FGFs. FGF-1 and S100A13
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Li R, Li W, He F, Zhang M, Luo H, Tang H. Li R, et al. J Oral Pathol Med. 2021 Oct;50(9):882-890. doi: 10.1111/jop.13224. Epub 2021 Aug 25. J Oral Pathol Med. 2021. PMID: 34358353
S100A13 knockdown increased cisplatin sensitivity, while its overexpression decreased the sensitivity of CAL-27 and SCC-4 cells. ...CONCLUSION: This study revealed a novel TEAD4-S100A13 axis that might modulate cisplatin sensitivity of OSCC tumor cells....
S100A13 knockdown increased cisplatin sensitivity, while its overexpression decreased the sensitivity of CAL-27 and SCC-4 cells. ...C
Overexpression of S100A13 protein is associated with tumor angiogenesis and poor survival in patients with early-stage non-small cell lung cancer.
Miao S, Qiu T, Zhao Y, Wang H, Sun X, Wang Y, Xuan Y, Qin Y, Jiao W. Miao S, et al. Thorac Cancer. 2018 Sep;9(9):1136-1144. doi: 10.1111/1759-7714.12797. Epub 2018 Jul 26. Thorac Cancer. 2018. PMID: 30047626 Free PMC article.
BACKGROUND: S100A13 plays a key role in tumor growth and metastasis. The purpose of this study was to investigate the prognostic significance of S100A13 expression, microvessel density (MVD), and survival in early stage non-small cell lung cancer (NSCLC). ...Paraffi …
BACKGROUND: S100A13 plays a key role in tumor growth and metastasis. The purpose of this study was to investigate the prognostic sign …
Wild-type S100A3 and S100A13 restore calcium homeostasis and mitigate mitochondrial dysregulation in pulmonary fibrosis patient-derived cells.
Al-Mutairy EA, Al Qattan S, Khalid M, Al-Enazi AA, Al-Saif MM, Imtiaz F, Ramzan K, Raveendran V, Alaiya A, Meyer BF, Atamas SP, Collison KS, Khabar KS, Hasday JD, Al-Mohanna F. Al-Mutairy EA, et al. Front Cell Dev Biol. 2023 Nov 30;11:1282868. doi: 10.3389/fcell.2023.1282868. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38099297 Free PMC article.
Patients with digenic S100A3 and S100A13 mutations exhibited an atypical and progressive interstitial pulmonary fibrosis, with impaired intracellular calcium homeostasis and mitochondrial dysfunction. Here we provide direct evidence of a causative effect of the mutation on …
Patients with digenic S100A3 and S100A13 mutations exhibited an atypical and progressive interstitial pulmonary fibrosis, with impair …
125 results