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Results: 1 to 20 of 50

1.

Cell cycle regulation of human DNA repair and chromatin remodeling genes.

Mjelle R, Hegre SA, Aas PA, Slupphaug G, Drabløs F, Saetrom P, Krokan HE.

DNA Repair (Amst). 2015 Jun;30:53-67. doi: 10.1016/j.dnarep.2015.03.007. Epub 2015 Mar 28.

2.

A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine.

Hansen MF, Johansen J, Bjørnevoll I, Sylvander AE, Steinsbekk KS, Sætrom P, Sandvik AK, Drabløs F, Sjursen W.

Fam Cancer. 2015 Apr 10. [Epub ahead of print]

PMID:
25860647
3.

AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.

Pettersen HS, Galashevskaya A, Doseth B, Sousa MM, Sarno A, Visnes T, Aas PA, Liabakk NB, Slupphaug G, Sætrom P, Kavli B, Krokan HE.

DNA Repair (Amst). 2015 Jan;25:60-71. doi: 10.1016/j.dnarep.2014.11.006. Epub 2014 Nov 24.

4.

Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA.

Reddy MA, Chen Z, Park JT, Wang M, Lanting L, Zhang Q, Bhatt K, Leung A, Wu X, Putta S, Sætrom P, Devaraj S, Natarajan R.

Diabetes. 2014 Dec;63(12):4249-61. doi: 10.2337/db14-0298. Epub 2014 Jul 9.

5.

Circular RNAs are depleted of polymorphisms at microRNA binding sites.

Thomas LF, Sætrom P.

Bioinformatics. 2014 Aug 15;30(16):2243-6. doi: 10.1093/bioinformatics/btu257. Epub 2014 Apr 24.

6.

Error-free versus mutagenic processing of genomic uracil--relevance to cancer.

Krokan HE, Sætrom P, Aas PA, Pettersen HS, Kavli B, Slupphaug G.

DNA Repair (Amst). 2014 Jul;19:38-47. doi: 10.1016/j.dnarep.2014.03.028. Epub 2014 Apr 18. Review.

7.

The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.

Razick S, Močnik R, Thomas LF, Ryeng E, Drabløs F, Sætrom P.

Database (Oxford). 2014 Mar 28;2014:bau027. doi: 10.1093/database/bau027. Print 2014.

8.

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.

Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, Flannick J, Zhang J, Fuchsberger C, Gaulton K, Lindgren C, Locke A, Manning A, Sim X, Rivas MA, Holmen OL, Gottesman O, Lu Y, Ruderfer D, Stahl EA, Duan Q, Li Y, Durda P, Jiao S, Isaacs A, Hofman A, Bis JC, Correa A, Griswold ME, Jakobsdottir J, Smith AV, Schreiner PJ, Feitosa MF, Zhang Q, Huffman JE, Crosby J, Wassel CL, Do R, Franceschini N, Martin LW, Robinson JG, Assimes TL, Crosslin DR, Rosenthal EA, Tsai M, Rieder MJ, Farlow DN, Folsom AR, Lumley T, Fox ER, Carlson CS, Peters U, Jackson RD, van Duijn CM, Uitterlinden AG, Levy D, Rotter JI, Taylor HA, Gudnason V Jr, Siscovick DS, Fornage M, Borecki IB, Hayward C, Rudan I, Chen YE, Bottinger EP, Loos RJ, Sætrom P, Hveem K, Boehnke M, Groop L, McCarthy M, Meitinger T, Ballantyne CM, Gabriel SB, O'Donnell CJ, Post WS, North KE, Reiner AP, Boerwinkle E, Psaty BM, Altshuler D, Kathiresan S, Lin DY, Jarvik GP, Cupples LA, Kooperberg C, Wilson JG, Nickerson DA, Abecasis GR, Rich SS, Tracy RP, Willer CJ; NHLBI Grand Opportunity Exome Sequencing Project.

Am J Hum Genet. 2014 Feb 6;94(2):233-45. doi: 10.1016/j.ajhg.2014.01.010.

9.

MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases.

Chavali S, Bruhn S, Tiemann K, Saetrom P, Barrenäs F, Saito T, Kanduri K, Wang H, Benson M.

RNA. 2013 Nov;19(11):1552-62. doi: 10.1261/rna.038414.113. Epub 2013 Sep 23.

10.

Exploiting human CD34+ stem cell-conditioned medium for tissue repair.

Mintz PJ, Huang KW, Reebye V, Nteliopoulos G, Lai HS, Sætrom P, Kasahara N, Jensen S, Pai M, Gordon MY, Marley SB, Behan R, Spalding DR, Haoudi A, Emara MM, Nicholls J, Rossi JJ, Habib NA.

Mol Ther. 2014 Jan;22(1):149-59. doi: 10.1038/mt.2013.194. Epub 2013 Aug 28.

11.

Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo.

Reebye V, Sætrom P, Mintz PJ, Huang KW, Swiderski P, Peng L, Liu C, Liu X, Lindkaer-Jensen S, Zacharoulis D, Kostomitsopoulos N, Kasahara N, Nicholls JP, Jiao LR, Pai M, Spalding DR, Mizandari M, Chikovani T, Emara MM, Haoudi A, Tomalia DA, Rossi JJ, Habib NA.

Hepatology. 2014 Jan;59(1):216-27. doi: 10.1002/hep.26669. Epub 2013 Dec 9.

PMID:
23929703
12.

A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells.

Reebye V, Sætrom P, Mintz PJ, Rossi JJ, Kasahara N, Nteliopoulos G, Nicholls J, Haoudi A, Gordon M, Habib NA.

Mol Ther Nucleic Acids. 2013 Jun 4;2:e97. doi: 10.1038/mtna.2013.23.

13.

Novel long noncoding RNAs are regulated by angiotensin II in vascular smooth muscle cells.

Leung A, Trac C, Jin W, Lanting L, Akbany A, Sætrom P, Schones DE, Natarajan R.

Circ Res. 2013 Jul 19;113(3):266-78. doi: 10.1161/CIRCRESAHA.112.300849. Epub 2013 May 22.

14.

Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells.

Voutila J, Sætrom P, Mintz P, Sun G, Alluin J, Rossi JJ, Habib NA, Kasahara N.

Mol Ther Nucleic Acids. 2012 Aug 7;1:e35. doi: 10.1038/mtna.2012.20.

15.

MicroRNA-181a* Targets Nanog in a Subpopulation of CD34(+) Cells Isolated From Peripheral Blood.

Mintz PJ, Sætrom P, Reebye V, Lundbæk MB, Lao K, Rossi JJ, Gaensler KM, Kasahara N, Nicholls JP, Jensen S, Haoudi A, Emara MM, Gordon MY, Habib NA.

Mol Ther Nucleic Acids. 2012 Aug 7;1:e34. doi: 10.1038/mtna.2012.29.

16.

Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication.

Peña-Diaz J, Hegre SA, Anderssen E, Aas PA, Mjelle R, Gilfillan GD, Lyle R, Drabløs F, Krokan HE, Sætrom P.

Nucleic Acids Res. 2013 Mar 1;41(5):2846-56. doi: 10.1093/nar/gks1336. Epub 2013 Jan 15.

17.

Multiple microRNAs may regulate the DNA repair enzyme uracil-DNA glycosylase.

Hegre SA, Sætrom P, Aas PA, Pettersen HS, Otterlei M, Krokan HE.

DNA Repair (Amst). 2013 Jan 1;12(1):80-6. doi: 10.1016/j.dnarep.2012.10.007. Epub 2012 Dec 8.

PMID:
23228472
18.

Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting.

Sætrom P.

Methods Mol Biol. 2013;942:169-77. doi: 10.1007/978-1-62703-119-6_9.

PMID:
23027051
19.

Single nucleotide polymorphisms can create alternative polyadenylation signals and affect gene expression through loss of microRNA-regulation.

Thomas LF, Sætrom P.

PLoS Comput Biol. 2012;8(8):e1002621. doi: 10.1371/journal.pcbi.1002621. Epub 2012 Aug 16.

20.

Cell-type specificity of ChIP-predicted transcription factor binding sites.

Håndstad T, Rye M, Močnik R, Drabløs F, Sætrom P.

BMC Genomics. 2012 Aug 3;13:372. doi: 10.1186/1471-2164-13-372.

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