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The Molecular Genetics of Restless Legs Syndrome.

Rye DB.

Sleep Med Clin. 2015 Sep;10(3):227-33, xii. doi: 10.1016/j.jsmc.2015.05.015. Epub 2015 Jul 2. Review.


Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial.

Trotti LM, Saini P, Bliwise DL, Freeman AA, Jenkins A, Rye DB.

Ann Neurol. 2015 Sep;78(3):454-65. doi: 10.1002/ana.24459. Epub 2015 Jun 30.


Inhibition of tumor necrosis factor improves sleep continuity in patients with treatment resistant depression and high inflammation.

Weinberger JF, Raison CL, Rye DB, Montague AR, Woolwine BJ, Felger JC, Haroon E, Miller AH.

Brain Behav Immun. 2015 Jul;47:193-200. doi: 10.1016/j.bbi.2014.12.016. Epub 2014 Dec 18.


Further experience using clarithromycin in patients with Kleine-Levin syndrome.

Trotti LM, Bliwise DL, Rye DB.

J Clin Sleep Med. 2014 Apr 15;10(4):457-8. doi: 10.5664/jcsm.3634. No abstract available.


Wavelet analysis for detection of phasic electromyographic activity in sleep: influence of mother wavelet and dimensionality reduction.

Fairley JA, Georgoulas G, Smart OL, Dimakopoulos G, Karvelis P, Stylios CD, Rye DB, Bliwise DL.

Comput Biol Med. 2014 May;48:77-84. doi: 10.1016/j.compbiomed.2013.12.011. Epub 2014 Jan 11.


Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience.

Trotti LM, Saini P, Freeman AA, Bliwise DL, García PS, Jenkins A, Rye DB.

J Psychopharmacol. 2013 Dec 3;28(7):697-702. [Epub ahead of print]


Test-retest reliability of the multiple sleep latency test in narcolepsy without cataplexy and idiopathic hypersomnia.

Trotti LM, Staab BA, Rye DB.

J Clin Sleep Med. 2013 Aug 15;9(8):789-95. doi: 10.5664/jcsm.2922.


The molecular basis of restless legs syndrome.

Freeman AA, Rye DB.

Curr Opin Neurobiol. 2013 Oct;23(5):895-900. doi: 10.1016/j.conb.2013.07.001. Epub 2013 Jul 26. Review.


Restless legs syndrome, pica, and iron status in blood donors.

Spencer BR, Kleinman S, Wright DJ, Glynn SA, Rye DB, Kiss JE, Mast AE, Cable RG; REDS-II RISE Analysis Group.

Transfusion. 2013 Aug;53(8):1645-52. doi: 10.1111/trf.12260. Epub 2013 Jun 13.


A prospective photographic study of the ocular fundus in obstructive sleep apnea.

Fraser CL, Bliwise DL, Newman NJ, Lamirel C, Collop NA, Rye DB, Trotti LM, Biousse V, Bruce BB.

J Neuroophthalmol. 2013 Sep;33(3):241-6. doi: 10.1097/WNO.0b013e318290194f.


Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates.

Felger JC, Mun J, Kimmel HL, Nye JA, Drake DF, Hernandez CR, Freeman AA, Rye DB, Goodman MM, Howell LL, Miller AH.

Neuropsychopharmacology. 2013 Oct;38(11):2179-87. doi: 10.1038/npp.2013.115. Epub 2013 May 9.


Obstructive sleep apnea in idiopathic intracranial hypertension: comparison with matched population data.

Thurtell MJ, Trotti LM, Bixler EO, Rye DB, Bliwise DL, Newman NJ, Biousse V, Bruce BB.

J Neurol. 2013 Jul;260(7):1748-51. doi: 10.1007/s00415-013-6858-6. Epub 2013 Feb 15.


Restless legs syndrome in children with chronic kidney disease.

Riar SK, Leu RM, Turner-Green TC, Rye DB, Kendrick-Allwood SR, McCracken C, Bliwise DL, Greenbaum LA.

Pediatr Nephrol. 2013 May;28(5):773-95. doi: 10.1007/s00467-013-2408-9. Epub 2013 Jan 20.


Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors.

Rye DB, Bliwise DL, Parker K, Trotti LM, Saini P, Fairley J, Freeman A, Garcia PS, Owens MJ, Ritchie JC, Jenkins A.

Sci Transl Med. 2012 Nov 21;4(161):161ra151. doi: 10.1126/scitranslmed.3004685.


Restless legs syndrome and periodic leg movements of sleep.

Rye DB, Trotti LM.

Neurol Clin. 2012 Nov;30(4):1137-66. doi: 10.1016/j.ncl.2012.08.004. Review.


Daytime REM sleep in Parkinson's disease.

Bliwise DL, Trotti LM, Juncos JJ, Factor SA, Freeman A, Rye DB.

Parkinsonism Relat Disord. 2013 Jan;19(1):101-3. doi: 10.1016/j.parkreldis.2012.08.003. Epub 2012 Aug 29.


Daytime alertness in Parkinson's disease: potentially dose-dependent, divergent effects by drug class.

Bliwise DL, Trotti LM, Wilson AG, Greer SA, Wood-Siverio C, Juncos JJ, Factor SA, Freeman A, Rye DB.

Mov Disord. 2012 Aug;27(9):1118-24. doi: 10.1002/mds.25082. Epub 2012 Jul 2.


Elevated C-reactive protein is associated with severe periodic leg movements of sleep in patients with restless legs syndrome.

Trotti LM, Rye DB, De Staercke C, Hooper WC, Quyyumi A, Bliwise DL.

Brain Behav Immun. 2012 Nov;26(8):1239-43. doi: 10.1016/j.bbi.2012.06.003. Epub 2012 Jun 26.


Sleep fragmentation and motor restlessness in a Drosophila model of Restless Legs Syndrome.

Freeman A, Pranski E, Miller RD, Radmard S, Bernhard D, Jinnah HA, Betarbet R, Rye DB, Sanyal S.

Curr Biol. 2012 Jun 19;22(12):1142-8. doi: 10.1016/j.cub.2012.04.027. Epub 2012 May 31.

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