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Results: 18

1.

MHC-I molecules selectively inhibit cell-mediated cytotoxicity triggered by ITAM-coupled activating receptors and 2B4.

Corral-San Miguel R, Hernández-Caselles T, Ruiz Alcaraz AJ, Martínez-Esparza M, García-Peñarrubia P.

PLoS One. 2014 Sep 16;9(9):e107054. doi: 10.1371/journal.pone.0107054. eCollection 2014.

PMID:
25226085
[PubMed - in process]
Free PMC Article
2.

Regulatory role of PI3K-protein kinase B on the release of interleukin-1β in peritoneal macrophages from the ascites of cirrhotic patients.

Tapia-Abellán A, Ruiz-Alcaraz AJ, Antón G, Miras-López M, Francés R, Such J, Martínez-Esparza M, García-Peñarrubia P.

Clin Exp Immunol. 2014 Dec;178(3):525-36. doi: 10.1111/cei.12428.

PMID:
25080058
[PubMed - in process]
3.

First synthesis and biological evaluation of 4-amino-2-aryl-6,9-dichlorobenzo[g]pteridines as inhibitors of TNF-α and IL-6.

Guirado A, López Sánchez JI, Ruiz-Alcaraz AJ, García-Peñarrubia P, Bautista D, Gálvez J.

Eur J Med Chem. 2013 Aug;66:269-75. doi: 10.1016/j.ejmech.2013.05.020. Epub 2013 May 24.

PMID:
23811089
[PubMed - indexed for MEDLINE]
4.

Obesity-induced insulin resistance in human skeletal muscle is characterised by defective activation of p42/p44 MAP kinase.

Ruiz-Alcaraz AJ, Lipina C, Petrie JR, Murphy MJ, Morris AD, Sutherland C, Cuthbertson DJ.

PLoS One. 2013;8(2):e56928. doi: 10.1371/journal.pone.0056928. Epub 2013 Feb 28.

PMID:
23468892
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Role of MAP kinases and PI3K-Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients.

Tapia-Abellán A, Ruiz-Alcaraz AJ, Hernández-Caselles T, Such J, Francés R, García-Peñarrubia P, Martínez-Esparza M.

Liver Int. 2013 Apr;33(4):552-60. doi: 10.1111/liv.12072. Epub 2013 Jan 20.

PMID:
23331611
[PubMed - indexed for MEDLINE]
6.

The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation.

Tapia-Abellán A, Martínez-Esparza M, Ruiz-Alcaraz AJ, Hernández-Caselles T, Martínez-Pascual C, Miras-López M, Such J, Francés R, García-Peñarrubia P.

BMC Immunol. 2012 Aug 6;13:42. doi: 10.1186/1471-2172-13-42.

PMID:
22866973
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Synthesis and biological evaluation of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines as inhibitors of TNF-α and IL-6.

Guirado A, López Sánchez JI, Ruiz-Alcaraz AJ, Bautista D, Gálvez J.

Eur J Med Chem. 2012 Aug;54:87-94. doi: 10.1016/j.ejmech.2012.04.035. Epub 2012 May 3.

PMID:
22621841
[PubMed - indexed for MEDLINE]
8.

Acquisition of MDR phenotype by leukemic cells is associated with increased caspase-3 activity and a collateral sensitivity to cold stress.

Cerezo D, Lencina M, Ruiz-Alcaraz AJ, Ferragut JA, Saceda M, Sanchez M, Cánovas M, García-Peñarrubia P, Martín-Orozco E.

J Cell Biochem. 2012 Apr;113(4):1416-25. doi: 10.1002/jcb.24016.

PMID:
22173742
[PubMed - indexed for MEDLINE]
9.

Peritoneal macrophage priming in cirrhosis is related to ERK phosphorylation and IL-6 secretion.

Ruiz-Alcaraz AJ, Martínez-Esparza M, Caño R, Hernández-Caselles T, Recarti C, Llanos L, Zapater P, Tapia-Abellán A, Martín-Orozco E, Pérez-Mateo M, Such J, García-Peñarrubia P, Francés R.

Eur J Clin Invest. 2011 Jan;41(1):8-15. doi: 10.1111/j.1365-2362.2010.02368.x. Epub 2010 Aug 19. Erratum in: Eur J Clin Invest. 2011 Apr;41(4):464. Tapia, Ana [corrected to Tapia-Abellán, Ana].

PMID:
20731703
[PubMed - indexed for MEDLINE]
10.

Generation, validation and humanisation of a novel insulin resistant cell model.

Logie L, Ruiz-Alcaraz AJ, Schofield CJ, Hundal HS, Feuerstein GZ, Brady JD, Crowther D, Tommasi AM, Grierson CE, Shepherd B, Morris AD, Hansen MK, Pearson E, Sutherland C.

Biochem Pharmacol. 2010 Oct 1;80(7):1042-9. doi: 10.1016/j.bcp.2010.06.011. Epub 2010 Jun 23.

PMID:
20599791
[PubMed - indexed for MEDLINE]
11.

Synthetic oligodeoxynucleotides induce MAP kinases activation in murine TIB-73 hepatocytes.

Martín-Orozco E, Chicano A, Ruiz-Alcaraz AJ, Lizana A, Martínez-Esparza M, Hernández-Caselles T, García-Peñarrubia P.

Histol Histopathol. 2010 Jul;25(7):831-40.

PMID:
20503172
[PubMed - indexed for MEDLINE]
12.

Norfloxacin modulates the inflammatory response and directly affects neutrophils in patients with decompensated cirrhosis.

Zapater P, Caño R, Llanos L, Ruiz-Alcaraz AJ, Pascual S, Barquero C, Moreu R, Bellot P, Horga JF, Muñoz C, Pérez J, García-Peñarrubia P, Pérez-Mateo M, Such J, Francés R.

Gastroenterology. 2009 Nov;137(5):1669-79.e1. doi: 10.1053/j.gastro.2009.07.058. Epub 2009 Aug 4.

PMID:
19660462
[PubMed - indexed for MEDLINE]
13.

Insulin resistance in polycystic ovary syndrome is associated with defective regulation of ERK1/2 by insulin in skeletal muscle in vivo.

Rajkhowa M, Brett S, Cuthbertson DJ, Lipina C, Ruiz-Alcaraz AJ, Thomas GE, Logie L, Petrie JR, Sutherland C.

Biochem J. 2009 Mar 15;418(3):665-71. doi: 10.1042/BJ20082176.

PMID:
19053948
[PubMed - indexed for MEDLINE]
Free Article
14.

Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells.

Logie L, Ruiz-Alcaraz AJ, Keane M, Woods YL, Bain J, Marquez R, Alessi DR, Sutherland C.

Diabetes. 2007 Sep;56(9):2218-27. Epub 2007 Jun 11.

PMID:
17563061
[PubMed - indexed for MEDLINE]
Free Article
15.

A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression.

Finlay D, Ruiz-Alcaraz AJ, Lipina C, Perrier S, Sutherland C.

J Mol Endocrinol. 2006 Oct;37(2):227-37.

PMID:
17032741
[PubMed - indexed for MEDLINE]
Free Article
16.

A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration.

Ruiz-Alcaraz AJ, Liu HK, Cuthbertson DJ, McManus EJ, Akhtar S, Lipina C, Morris AD, Petrie JR, Hundal HS, Sutherland C.

Biochem J. 2005 Dec 1;392(Pt 2):345-52.

PMID:
16128672
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Gonadins, a novel family of glutamyl-tripeptide amides present in the testis with activity in the hypophyseal-gonadal axis.

Ruiz-Alcaraz AJ, Del Rio-Garcia J.

Regul Pept. 2005 Jul 15;129(1-3):93-101.

PMID:
15927703
[PubMed - indexed for MEDLINE]
18.

Characterization of a circulating N-extended form of the thyrotropin-releasing hormone-like peptide pGlu-Glu-Pro amide in human plasma.

Ruiz-Alcaraz AJ, del Rio-Garcia J.

J Clin Endocrinol Metab. 2003 Dec;88(12):6002-7.

PMID:
14671203
[PubMed - indexed for MEDLINE]
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