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Nerve Transfer for Facial Paralysis Under Intravenous Sedation and Local Analgesia for the High Surgical Risk Elderly Patient.

Rubi C, Cardenas Mejia A, Cavadas PC, Thione A, Aramburo Garcia R, Rozen S.

World Neurosurg. 2016 Apr 7. pii: S1878-8750(16)30018-3. doi: 10.1016/j.wneu.2016.03.091. [Epub ahead of print]


MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex.

Zhang W, Kim PJ, Chen Z, Lokman H, Qiu L, Zhang K, Rozen SG, Tan EK, Je HS, Zeng L.

Elife. 2016 Feb 17;5. pii: e11324. doi: 10.7554/eLife.11324.


JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma.

Nairismägi ML, Tan J, Lim JQ, Nagarajan S, Ng CC, Rajasegaran V, Huang D, Lim WK, Laurensia Y, Wijaya GC, Li ZM, Cutcutache I, Pang WL, Thangaraju S, Ha J, Khoo LP, Chin ST, Dey S, Poore G, Tan LH, Koh HK, Sabai K, Rao HL, Chuah KL, Ho YH, Ng SB, Chuang SS, Zhang F, Liu YH, Pongpruttipan T, Ko YH, Cheah PL, Karim N, Chng WJ, Tang T, Tao M, Tay K, Farid M, Quek R, Rozen SG, Tan P, Teh BT, Lim ST, Tan SY, Ong CK.

Leukemia. 2016 Feb 8. doi: 10.1038/leu.2016.13. [Epub ahead of print]


NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition.

Madan B, Ke Z, Lei ZD, Oliver FA, Oshima M, Lee MA, Rozen S, Virshup DM.

Oncotarget. 2016 Mar 15;7(11):12386-92. doi: 10.18632/oncotarget.7157.


Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways.

Thurnherr T, Mah WC, Lei Z, Jin Y, Rozen SG, Lee CG.

Sci Rep. 2016 Jan 28;6:20065. doi: 10.1038/srep20065.


Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck.

Huang KK, Jang KW, Kim S, Kim HS, Kim SM, Kwon HJ, Kim HR, Yun HJ, Ahn MJ, Park KU, Ramnarayanan K, McPherson JR, Zhang S, Rhee JK, Vettore AL, Das K, Ishimoto T, Kim JH, Koh YW, Kim SH, Choi EC, Teh BT, Rozen SG, Kim TM, Tan P, Cho BC.

Sci Rep. 2016 Jan 21;6:19552. doi: 10.1038/srep19552.


Intracranial Facial Nerve Grafting in the Setting of Skull Base Tumors: Global and Regional Facial Function Analysis and Possible Implications for Facial Reanimation Surgery.

Rozen SM, Harrison BL, Isaacson B, Kutz JW Jr, Roland PS, Blau PA, Barnett SL, Mickey BE.

Plast Reconstr Surg. 2016 Jan;137(1):267-78. doi: 10.1097/PRS.0000000000001881.


CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome.

Rozen S, Füzesi-Levi MG, Ben-Nissan G, Mizrachi L, Gabashvili A, Levin Y, Ben-Dor S, Eisenstein M, Sharon M.

Cell Rep. 2015 Oct 20;13(3):585-98. doi: 10.1016/j.celrep.2015.09.021. Epub 2015 Oct 8.


Genomic landscapes of breast fibroepithelial tumors.

Tan J, Ong CK, Lim WK, Ng CC, Thike AA, Ng LM, Rajasegaran V, Myint SS, Nagarajan S, Thangaraju S, Dey S, Nasir ND, Wijaya GC, Lim JQ, Huang D, Li Z, Wong BH, Chan JY, McPherson JR, Cutcutache I, Poore G, Tay ST, Tan WJ, Putti TC, Ahmad BS, Iau P, Chan CW, Tang AP, Yong WS, Madhukumar P, Ho GH, Tan VK, Wong CY, Hartman M, Ong KW, Tan BK, Rozen SG, Tan P, Tan PH, Teh BT.

Nat Genet. 2015 Nov;47(11):1341-5. doi: 10.1038/ng.3409. Epub 2015 Oct 5.


Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.

McPherson JR, Ong CK, Ng CC, Rajasegaran V, Heng HL, Yu WS, Tan BK, Madhukumar P, Teo MC, Ngeow J, Thike AA, Rozen SG, Tan PH, Lee AS, Teh BT, Yap YS.

Cancer Med. 2015 Dec;4(12):1871-8. doi: 10.1002/cam4.551. Epub 2015 Oct 3.


Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.

Vettore AL, Ramnarayanan K, Poore G, Lim K, Ong CK, Huang KK, Leong HS, Chong FT, Lim TK, Lim WK, Cutcutache I, Mcpherson JR, Suzuki Y, Zhang S, Skanthakumar T, Wang W, Tan DS, Cho BC, Teh BT, Rozen S, Tan P, Iyer NG.

Genome Med. 2015 Sep 23;7:98. doi: 10.1186/s13073-015-0219-2.


SETD2 histone modifier loss in aggressive GI stromal tumours.

Huang KK, McPherson JR, Tay ST, Das K, Tan IB, Ng CC, Chia NY, Zhang SL, Myint SS, Hu L, Rajasegaran V, Huang D, Loh JL, Gan A, Sairi AN, Sam XX, Dominguez LT, Lee M, Soo KC, Ooi LL, Ong HS, Chung A, Chow PK, Wong WK, Selvarajan S, Ong CK, Lim KH, Nandi T, Rozen S, Teh BT, Quek R, Tan P.

Gut. 2015 Sep 3. pii: gutjnl-2015-309482. doi: 10.1136/gutjnl-2015-309482. [Epub ahead of print]


MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations.

Huang MN, McPherson JR, Cutcutache I, Teh BT, Tan P, Rozen SG.

Sci Rep. 2015 Aug 26;5:13321. doi: 10.1038/srep13321.


The Evolutionary Potential of Phenotypic Mutations.

Yanagida H, Gispan A, Kadouri N, Rozen S, Sharon M, Barkai N, Tawfik DS.

PLoS Genet. 2015 Aug 5;11(8):e1005445. doi: 10.1371/journal.pgen.1005445. eCollection 2015 Aug.


Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma.

Cutcutache I, Wu AY, Suzuki Y, McPherson JR, Lei Z, Deng N, Zhang S, Wong WK, Soo KC, Chan WH, Ooi LL, Welsch R, Tan P, Rozen SG.

Gastric Cancer. 2016 Apr;19(2):453-65. doi: 10.1007/s10120-015-0514-z. Epub 2015 Jul 24.


Fanconi anemia gene variants in therapy-related myeloid neoplasms.

Voso MT, Fabiani E, Zang Z, Fianchi L, Falconi G, Padella A, Martini M, Li Zhang S, Santangelo R, Larocca LM, Criscuolo M, La Brocca A, Cutcutache I, Rozen S, Simonetti G, Manfrini M, Martinelli G, Hohaus S, Leone G, Tan P, Tenen DG.

Blood Cancer J. 2015 Jul 3;5:e323. doi: 10.1038/bcj.2015.44. No abstract available.


TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.

Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ.

EMBO Mol Med. 2015 Jul 1;7(9):1198-210. doi: 10.15252/emmm.201404967.


Influence of using a single facial vein as outflow in full-face transplantation: A three-dimensional computed tomographic study.

Rodriguez-Lorenzo A, Audolfsson T, Wong C, Cheng A, Arbique G, Nowinski D, Rozen S.

J Plast Reconstr Aesthet Surg. 2015 Oct;68(10):1358-63. doi: 10.1016/j.bjps.2015.05.031. Epub 2015 Jun 5.


Mutation signatures implicate aristolochic acid in bladder cancer development.

Poon SL, Huang MN, Choo Y, McPherson JR, Yu W, Heng HL, Gan A, Myint SS, Siew EY, Ler LD, Ng LG, Weng WH, Chuang CK, Yuen JS, Pang ST, Tan P, Teh BT, Rozen SG.

Genome Med. 2015 Apr 28;7(1):38. doi: 10.1186/s13073-015-0161-3. eCollection 2015.


Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways.

Kongpetch S, Jusakul A, Ong CK, Lim WK, Rozen SG, Tan P, Teh BT.

Best Pract Res Clin Gastroenterol. 2015 Apr;29(2):233-44. doi: 10.1016/j.bpg.2015.02.002. Epub 2015 Feb 17. Review.

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