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Results: 1 to 20 of 159


High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Tan IB, Malik S, Ramnarayanan K, McPherson JR, Ho DL, Suzuki Y, Ng SB, Yan S, Lim KH, Koh D, Hoe CM, Chan CY, Ten R, Goh BK, Chung AY, Tan J, Chan CX, Tay ST, Alexander L, Nagarajan N, Hillmer AM, Tang CL, Chua C, Teh BT, Rozen S, Tan P.

Genome Biol. 2015 Feb 12;16(1):32. doi: 10.1186/s13059-015-0589-1.


Three-Dimensional MR Neurography of the Lumbosacral Plexus.

Chhabra A, Rozen S, Scott K.

Semin Musculoskelet Radiol. 2015 Apr;19(2):149-59. doi: 10.1055/s-0035-1545077. Epub 2015 Mar 12.


SHINKEI-a novel 3D isotropic MR neurography technique: technical advantages over 3DIRTSE-based imaging.

Kasper JM, Wadhwa V, Scott KM, Rozen S, Xi Y, Chhabra A.

Eur Radiol. 2015 Feb 1. [Epub ahead of print]


Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas.

Cutcutache I, Suzuki Y, Tan IB, Ramgopal S, Zhang S, Ramnarayanan K, Gan A, Lee HH, Tay ST, Ooi A, Ong CK, Bolthouse JT, Lane BR, Anema JG, Kahnoski RJ, Tan P, Teh BT, Rozen SG.

Eur Urol. 2015 Jan 14. pii: S0302-2838(14)01396-7. doi: 10.1016/j.eururo.2014.12.040. [Epub ahead of print]


Computed-tomography modeled polyether ether ketone (PEEK) implants in revision cranioplasty.

O'Reilly EB, Barnett S, Madden C, Welch B, Mickey B, Rozen S.

J Plast Reconstr Aesthet Surg. 2015 Mar;68(3):329-38. doi: 10.1016/j.bjps.2014.11.001. Epub 2014 Nov 21.


Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.

Keck MK, Zuo Z, Khattri A, Stricker TP, Brown CD, Imanguli M, Rieke D, Endhardt K, Fang P, Brägelmann J, DeBoer R, El-Dinali M, Aktolga S, Lei Z, Tan P, Rozen SG, Salgia R, Weichselbaum RR, Lingen MW, Story MD, Ang KK, Cohen EE, White KP, Vokes EE, Seiwert TY.

Clin Cancer Res. 2015 Feb 15;21(4):870-81. doi: 10.1158/1078-0432.CCR-14-2481. Epub 2014 Dec 9.


Double innervated free functional muscle transfer for facial reanimation.

Cardenas-Mejia A, Covarrubias-Ramirez JV, Bello-Margolis A, Rozen S.

J Plast Surg Hand Surg. 2014 Dec 3:1-6. [Epub ahead of print]


Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes.

Soh YQ, Alföldi J, Pyntikova T, Brown LG, Graves T, Minx PJ, Fulton RS, Kremitzki C, Koutseva N, Mueller JL, Rozen S, Hughes JF, Owens E, Womack JE, Murphy WJ, Cao Q, de Jong P, Warren WC, Wilson RK, Skaletsky H, Page DC.

Cell. 2014 Nov 6;159(4):800-13. doi: 10.1016/j.cell.2014.09.052. Epub 2014 Oct 30.


Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.

Yu W, McPherson JR, Stevenson M, van Eijk R, Heng HL, Newey P, Gan A, Ruano D, Huang D, Poon SL, Ong CK, van Wezel T, Cavaco B, Rozen SG, Tan P, Teh BT, Thakker RV, Morreau H.

J Clin Endocrinol Metab. 2015 Feb;100(2):E360-4. doi: 10.1210/jc.2014-3238. Epub 2014 Nov 11.


General synthesis of trifluoromethyl selenides utilizing selenocyanates and fluoroform.

Potash S, Rozen S.

J Org Chem. 2014 Nov 21;79(22):11205-8. doi: 10.1021/jo5022844. Epub 2014 Nov 12.


Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming.

Fan Y, Marcy G, Lee ES, Rozen S, Mattar CN, Waddington SN, Goh EL, Choolani M, Chan JK.

PLoS One. 2014 Sep 2;9(9):e105985. doi: 10.1371/journal.pone.0105985. eCollection 2014.


Vastus lateralis vascularized nerve graft in facial nerve reconstruction: an anatomical cadaveric study and clinical implications.

Agrogiannis N, Rozen S, Reddy G, Audolfsson T, Rodriguez-Lorenzo A.

Microsurgery. 2015 Feb;35(2):135-9. doi: 10.1002/micr.22311. Epub 2014 Aug 20.


Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.

Chia NY, Deng N, Das K, Huang D, Hu L, Zhu Y, Lim KH, Lee MH, Wu J, Sam XX, Tan GS, Wan WK, Yu W, Gan A, Tan AL, Tay ST, Soo KC, Wong WK, Dominguez LT, Ng HH, Rozen S, Goh LK, Teh BT, Tan P.

Gut. 2015 May;64(5):707-19. doi: 10.1136/gutjnl-2013-306596. Epub 2014 Jul 22.


Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

Lim WK, Ong CK, Tan J, Thike AA, Ng CC, Rajasegaran V, Myint SS, Nagarajan S, Nasir ND, McPherson JR, Cutcutache I, Poore G, Tay ST, Ooi WS, Tan VK, Hartman M, Ong KW, Tan BK, Rozen SG, Tan PH, Tan P, Teh BT.

Nat Genet. 2014 Aug;46(8):877-80. doi: 10.1038/ng.3037. Epub 2014 Jul 20.


Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention.

Poon SL, McPherson JR, Tan P, Teh BT, Rozen SG.

Genome Med. 2014 Mar 31;6(3):24. doi: 10.1186/gm541. eCollection 2014. Review.


The NF1 gene revisited - from bench to bedside.

Yap YS, McPherson JR, Ong CK, Rozen SG, Teh BT, Lee AS, Callen DF.

Oncotarget. 2014 Aug 15;5(15):5873-92.


Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.

Muratani M, Deng N, Ooi WF, Lin SJ, Xing M, Xu C, Qamra A, Tay ST, Malik S, Wu J, Lee MH, Zhang S, Tan LL, Chua H, Wong WK, Ong HS, Ooi LL, Chow PK, Chan WH, Soo KC, Goh LK, Rozen S, Teh BT, Yu Q, Ng HH, Tan P.

Nat Commun. 2014 Jul 10;5:4361. doi: 10.1038/ncomms5361.


Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes.

Yeo ZX, Wong JC, Rozen SG, Lee AS.

BMC Genomics. 2014 Jun 24;15:516. doi: 10.1186/1471-2164-15-516.


Fluorination of flavones and chromones using elemental fluorine.

Vints I, Rozen S.

J Org Chem. 2014 Aug 15;79(16):7261-5. doi: 10.1021/jo5009542. Epub 2014 Jun 12.


HOF·CH3CN: probably the best oxygen transfer agent organic chemistry has to offer.

Rozen S.

Acc Chem Res. 2014 Aug 19;47(8):2378-89. doi: 10.1021/ar500107b. Epub 2014 May 28.

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