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    Results: 1 to 20 of 77

    1.

    DNA-damage-induced differentiation in hematopoietic stem cells.

    Mandal PK, Rossi DJ.

    Cell. 2012 Mar 2;148(5):847-8. doi: 10.1016/j.cell.2012.02.011.

    PMID:
    22385954
    [PubMed - indexed for MEDLINE]
    2.

    DNA damage response in adult stem cells: pathways and consequences.

    Mandal PK, Blanpain C, Rossi DJ.

    Nat Rev Mol Cell Biol. 2011 Mar;12(3):198-202. doi: 10.1038/nrm3060. Epub 2011 Feb 9.

    PMID:
    21304553
    [PubMed - indexed for MEDLINE]
    3.

    Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

    Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ.

    Cell Stem Cell. 2010 Nov 5;7(5):618-30. doi: 10.1016/j.stem.2010.08.012. Epub 2010 Sep 30.

    PMID:
    20888316
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Reprogramming human fibroblasts to pluripotency using modified mRNA.

    Mandal PK, Rossi DJ.

    Nat Protoc. 2013 Mar;8(3):568-82. doi: 10.1038/nprot.nprot.2013.019. Epub 2013 Feb 21.

    PMID:
    23429718
    [PubMed - in process]
    5.

    Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

    Rossi DJ, Seita J, Czechowicz A, Bhattacharya D, Bryder D, Weissman IL.

    Cell Cycle. 2007 Oct 1;6(19):2371-6. Epub 2007 Jul 18.

    PMID:
    17700071
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    DNA methylation dynamics during in vivo differentiation of blood and skin stem cells.

    Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, Meissner A.

    Mol Cell. 2012 Aug 24;47(4):633-47. doi: 10.1016/j.molcel.2012.06.019. Epub 2012 Jul 26.

    PMID:
    22841485
    [PubMed - indexed for MEDLINE]
    7.

    Hematopoietic stem cells and the aging hematopoietic system.

    Gazit R, Weissman IL, Rossi DJ.

    Semin Hematol. 2008 Oct;45(4):218-24. doi: 10.1053/j.seminhematol.2008.07.010. Review.

    PMID:
    18809091
    [PubMed - indexed for MEDLINE]
    8.

    Stem cells and aging in the hematopoietic system.

    Warren LA, Rossi DJ.

    Mech Ageing Dev. 2009 Jan-Feb;130(1-2):46-53. doi: 10.1016/j.mad.2008.03.010. Epub 2008 Apr 8. Review.

    PMID:
    18479735
    [PubMed - indexed for MEDLINE]
    9.

    Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.

    Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL.

    Nature. 2007 Jun 7;447(7145):725-9.

    PMID:
    17554309
    [PubMed - indexed for MEDLINE]
    10.

    Stem cells and the aging hematopoietic system.

    Beerman I, Maloney WJ, Weissmann IL, Rossi DJ.

    Curr Opin Immunol. 2010 Aug;22(4):500-6. doi: 10.1016/j.coi.2010.06.007. Epub 2010 Jul 23. Review.

    PMID:
    20650622
    [PubMed - indexed for MEDLINE]
    11.

    Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.

    Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, Rossi DJ.

    Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5465-70. doi: 10.1073/pnas.1000834107. Epub 2010 Mar 18.

    PMID:
    20304793
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Stems cells and the pathways to aging and cancer.

    Rossi DJ, Jamieson CH, Weissman IL.

    Cell. 2008 Feb 22;132(4):681-96. doi: 10.1016/j.cell.2008.01.036. Review.

    PMID:
    18295583
    [PubMed - indexed for MEDLINE]
    13.

    Gene Expression Commons: an open platform for absolute gene expression profiling.

    Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL.

    PLoS One. 2012;7(7):e40321. doi: 10.1371/journal.pone.0040321. Epub 2012 Jul 18.

    PMID:
    22815738
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    Niche recycling through division-independent egress of hematopoietic stem cells.

    Bhattacharya D, Czechowicz A, Ooi AG, Rossi DJ, Bryder D, Weissman IL.

    J Exp Med. 2009 Nov 23;206(12):2837-50. doi: 10.1084/jem.20090778. Epub 2009 Nov 2.

    PMID:
    19887396
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

    Pang WW, Price EA, Sahoo D, Beerman I, Maloney WJ, Rossi DJ, Schrier SL, Weissman IL.

    Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20012-7. doi: 10.1073/pnas.1116110108. Epub 2011 Nov 28.

    PMID:
    22123971
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    16.

    Differential DNA damage response in stem and progenitor cells.

    Seita J, Rossi DJ, Weissman IL.

    Cell Stem Cell. 2010 Aug 6;7(2):145-7. doi: 10.1016/j.stem.2010.07.006.

    PMID:
    20682442
    [PubMed]
    17.

    Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.

    Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ.

    Cell Stem Cell. 2013 Apr 4;12(4):413-25. doi: 10.1016/j.stem.2013.01.017. Epub 2013 Feb 14.

    PMID:
    23415915
    [PubMed - in process]
    18.

    Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.

    Bhattacharya D, Bryder D, Rossi DJ, Weissman IL.

    Cell Cycle. 2006 Jun;5(11):1135-9. Epub 2006 Jun 1.

    PMID:
    16760650
    [PubMed - indexed for MEDLINE]
    Free Article
    19.

    Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML.

    Vo TT, Ryan J, Carrasco R, Neuberg D, Rossi DJ, Stone RM, Deangelo DJ, Frattini MG, Letai A.

    Cell. 2012 Oct 12;151(2):344-55. doi: 10.1016/j.cell.2012.08.038.

    PMID:
    23063124
    [PubMed - indexed for MEDLINE]
    20.

    Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.

    Bhattacharya D, Rossi DJ, Bryder D, Weissman IL.

    J Exp Med. 2006 Jan 23;203(1):73-85. Epub 2005 Dec 27.

    PMID:
    16380511
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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