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Results: 1 to 20 of 148

1.

Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.

Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, Roels F, Wüstefeld T, Fischer M, Teichmann M, Zender L, Wei CL, Sansom O, Wolf E, Eilers M.

Nature. 2014 Jul 24;511(7510):483-7. doi: 10.1038/nature13473. Epub 2014 Jul 9.

PMID:
25043018
[PubMed - in process]
2.

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

Fabian J, Lodrini M, Oehme I, Schier MC, Thole TM, Hielscher T, Kopp-Schneider A, Opitz L, Capper D, von Deimling A, Wiegand I, Milde T, Mahlknecht U, Westermann F, Popanda O, Roels F, Hero B, Berthold F, Fischer M, Kulozik AE, Witt O, Deubzer HE.

Cancer Res. 2014 May 1;74(9):2604-16. doi: 10.1158/0008-5472.CAN-13-1904. Epub 2014 Jan 13.

PMID:
24419085
[PubMed - indexed for MEDLINE]
3.

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.

Brockmann M, Poon E, Berry T, Carstensen A, Deubzer HE, Rycak L, Jamin Y, Thway K, Robinson SP, Roels F, Witt O, Fischer M, Chesler L, Eilers M.

Cancer Cell. 2013 Jul 8;24(1):75-89. doi: 10.1016/j.ccr.2013.05.005. Epub 2013 Jun 20.

PMID:
23792191
[PubMed - indexed for MEDLINE]
4.

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.

Kocak H, Ackermann S, Hero B, Kahlert Y, Oberthuer A, Juraeva D, Roels F, Theissen J, Westermann F, Deubzer H, Ehemann V, Brors B, Odenthal M, Berthold F, Fischer M.

Cell Death Dis. 2013 Apr 11;4:e586. doi: 10.1038/cddis.2013.84.

PMID:
23579273
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Iodine-123 metaiodobenzylguanidine scintigraphy scoring allows prediction of outcome in patients with stage 4 neuroblastoma: results of the Cologne interscore comparison study.

Decarolis B, Schneider C, Hero B, Simon T, Volland R, Roels F, Dietlein M, Berthold F, Schmidt M.

J Clin Oncol. 2013 Mar 1;31(7):944-51. doi: 10.1200/JCO.2012.45.8794. Epub 2013 Jan 22.

PMID:
23341514
[PubMed - indexed for MEDLINE]
6.

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.

Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T.

EMBO J. 2012 Oct 17;31(20):3961-75. doi: 10.1038/emboj.2012.236. Epub 2012 Aug 21.

PMID:
22909821
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells.

Bruns I, Cadeddu RP, Brueckmann I, Fröbel J, Geyh S, Büst S, Fischer JC, Roels F, Wilk CM, Schildberg FA, Hünerlitürkoglu AN, Zilkens C, Jäger M, Steidl U, Zohren F, Fenk R, Kobbe G, Brors B, Czibere A, Schroeder T, Trumpp A, Haas R.

Blood. 2012 Sep 27;120(13):2620-30. Epub 2012 Apr 18.

PMID:
22517906
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Polymerase gamma deficiency (POLG): clinical course in a child with a two stage evolution from infantile myocerebrohepatopathy spectrum to an Alpers syndrome and neuropathological findings of Leigh's encephalopathy.

Scalais E, Francois B, Schlesser P, Stevens R, Nuttin C, Martin JJ, Van Coster R, Seneca S, Roels F, Van Goethem G, Löfgren A, De Meirleir L.

Eur J Paediatr Neurol. 2012 Sep;16(5):542-8. doi: 10.1016/j.ejpn.2012.01.013. Epub 2012 Feb 17.

PMID:
22342071
[PubMed - indexed for MEDLINE]
9.

Mitochondrial mosaics in the liver of 3 infants with mtDNA defects.

Roels F, Verloo P, Eyskens F, François B, Seneca S, De Paepe B, Martin JJ, Meersschaut V, Praet M, Scalais E, Espeel M, Smet J, Van Goethem G, Van Coster R.

BMC Clin Pathol. 2009 Jun 5;9:4. doi: 10.1186/1472-6890-9-4.

PMID:
19500334
[PubMed]
Free PMC Article
10.

The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecting loss of quiescence.

Bruns I, Czibere A, Fischer JC, Roels F, Cadeddu RP, Buest S, Bruennert D, Huenerlituerkoglu AN, Stoecklein NH, Singh R, Zerbini LF, Jäger M, Kobbe G, Gattermann N, Kronenwett R, Brors B, Haas R.

Leukemia. 2009 May;23(5):892-9. doi: 10.1038/leu.2008.392. Epub 2009 Jan 22.

PMID:
19158832
[PubMed - indexed for MEDLINE]
11.

Hepatocellular transport and gastrointestinal absorption of lanthanum in chronic renal failure.

Bervoets AR, Behets GJ, Schryvers D, Roels F, Yang Z, Verberckmoes SC, Damment SJ, Dauwe S, Mubiana VK, Blust R, De Broe ME, D'Haese PC.

Kidney Int. 2009 Feb;75(4):389-98. doi: 10.1038/ki.2008.571. Epub 2008 Dec 3.

PMID:
19052535
[PubMed - indexed for MEDLINE]
12.

Demonstration of lanthanum in liver cells by energy-dispersive X-ray spectroscopy, electron energy loss spectroscopy and high-resolution transmission electron microscopy.

Yang Z, Schryvers D, Roels F, D'Haese PC, De Broe ME.

J Microsc. 2006 Aug;223(Pt 2):133-9.

PMID:
16911073
[PubMed - indexed for MEDLINE]
13.

Intra-familial clinical heterogeneity: absence of genotype-phenotype correlation in primary hyperoxaluria type 1 in Israel.

Frishberg Y, Rinat C, Shalata A, Khatib I, Feinstein S, Becker-Cohen R, Weismann I, Wanders RJ, Rumsby G, Roels F, Mandel H.

Am J Nephrol. 2005 May-Jun;25(3):269-75. Epub 2005 Jun 15.

PMID:
15961946
[PubMed - indexed for MEDLINE]
14.

Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator.

Gondcaille C, Depreter M, Fourcade S, Lecca MR, Leclercq S, Martin PG, Pineau T, Cadepond F, ElEtr M, Bertrand N, Beley A, Duclos S, De Craemer D, Roels F, Savary S, Bugaut M.

J Cell Biol. 2005 Apr 11;169(1):93-104. Epub 2005 Apr 4.

PMID:
15809314
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

No evidence for involvement of SDHD in neuroblastoma pathogenesis.

De Preter K, Vandesompele J, Hoebeeck J, Vandenbroecke C, Smet J, Nuyts A, Laureys G, Combaret V, Van Roy N, Roels F, Van Coster R, Praet M, De Paepe A, Speleman F.

BMC Cancer. 2004 Aug 24;4:55.

PMID:
15331017
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Evaluation of the preventive effect of glyceryl trioleate-trierucate ("Lorenzo's oil") therapy in X-linked adrenoleukodystrophy: results of two concurrent trials.

Moser HW, Raymond GV, Koehler W, Sokolowski P, Hanefeld F, Korenke GC, Green A, Loes DJ, Hunneman DH, Jones RO, Lu SE, Uziel G, Giros ML, Roels F.

Adv Exp Med Biol. 2003;544:369-87. No abstract available.

PMID:
14713253
[PubMed - indexed for MEDLINE]
17.

Pharmacological induction of redundant genes for a therapy of X-ALD: phenylbutyrate and other compounds.

Bugaut M, Fourcade S, Gondcaille C, Gueugnon F, Depreter M, Roels F, Netik A, Berger J, Martin P, Pineau T, Cadepond F, El Etr M, Savary S.

Adv Exp Med Biol. 2003;544:281-91. Review. No abstract available.

PMID:
14713242
[PubMed - indexed for MEDLINE]
18.

Modified peroxisomes in primary hepatocyte cultures.

Depreter M, Walker T, Beken S, De Smet K, Papeleu P, Tytgat T, Espeel M, Rogiers V, Roels F.

Adv Exp Med Biol. 2003;544:255-64. No abstract available.

PMID:
14713239
[PubMed - indexed for MEDLINE]
19.

Regulation of peroxisomal genes by DHEA and vitamin D.

Depreter M, Vandesompele J, Ferdinandusse S, Speleman F, Roels F.

Adv Exp Med Biol. 2003;544:237-42. No abstract available.

PMID:
14713235
[PubMed - indexed for MEDLINE]
20.

Resolution of the molecular defect in a patient with peroxisomal mosaicism in the liver.

Gootjes J, Mandel H, Mooijer PA, Roels F, Waterham HR, Wanders RJ.

Adv Exp Med Biol. 2003;544:107-11. No abstract available.

PMID:
14713221
[PubMed - indexed for MEDLINE]

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