Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 65

1.

Prediction of distal residue participation in enzyme catalysis.

Brodkin HR, DeLateur NA, Somarowthu S, Mills CL, Novak WR, Beuning PJ, Ringe D, Ondrechen MJ.

Protein Sci. 2015 May;24(5):762-78. doi: 10.1002/pro.2648. Epub 2015 Apr 2.

2.

Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR.

Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS.

Structure. 2014 Jun 10;22(6):899-910. doi: 10.1016/j.str.2014.04.016. Epub 2014 May 29.

3.

Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2.

Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, Valinetz E, Brandt GS, Yu S, Shabashvili DE, Ringe D, Dunn BM, Petsko GA, Rengarajan J.

PLoS Pathog. 2014 May 15;10(5):e1004132. doi: 10.1371/journal.ppat.1004132. eCollection 2014 May.

4.

Pharmacological chaperones stabilize retromer to limit APP processing.

Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA.

Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20.

5.

Structure of a eukaryotic thiaminase I.

Kreinbring CA, Remillard SP, Hubbard P, Brodkin HR, Leeper FJ, Hawksley D, Lai EY, Fulton C, Petsko GA, Ringe D.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):137-42. doi: 10.1073/pnas.1315882110. Epub 2013 Dec 18.

6.

Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT.

Edayathumangalam R, Wu R, Garcia R, Wang Y, Wang W, Kreinbring CA, Bach A, Liao J, Stone TA, Terwilliger TC, Hoang QQ, Belitsky BR, Petsko GA, Ringe D, Liu D.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17820-5. doi: 10.1073/pnas.1315887110. Epub 2013 Oct 14.

7.

Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.

Auclair JR, Johnson JL, Liu Q, Salisbury JP, Rotunno MS, Petsko GA, Ringe D, Brown RH Jr, Bosco DA, Agar JN.

Biochemistry. 2013 Sep 10;52(36):6137-44. doi: 10.1021/bi4006122. Epub 2013 Aug 26.

8.

Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase.

Auclair JR, Brodkin HR, D'Aquino JA, Petsko GA, Ringe D, Agar JN.

Biochemistry. 2013 Sep 10;52(36):6145-50. doi: 10.1021/bi400613h. Epub 2013 Aug 26.

9.

Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site.

Sigala PA, Fafarman AT, Schwans JP, Fried SD, Fenn TD, Caaveiro JM, Pybus B, Ringe D, Petsko GA, Boxer SG, Herschlag D.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2552-61. doi: 10.1073/pnas.1302191110. Epub 2013 Jun 24.

10.

A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis.

Liu CF, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D.

Biochemistry. 2013 Mar 5;52(9):1603-10. doi: 10.1021/bi400050j. Epub 2013 Feb 20.

11.

Open questions - in brief: beyond -omics, missing motor proteins, and getting from molecules to organisms.

Benkovic SJ, Theriot J, Ringe D.

BMC Biol. 2013 Jan 31;11:8. doi: 10.1186/1741-7007-11-8. No abstract available.

12.

Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN.

J Alzheimers Dis. 2012;32(4):949-67. doi: 10.3233/JAD-2012-120178.

13.

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.

Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S.

Mol Psychiatry. 2013 Aug;18(8):882-8. doi: 10.1038/mp.2012.115. Epub 2012 Aug 7.

14.

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.

Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Fraser P, Westaway D, St George-Hyslop PH, Szabo P, Relkin NR, Buxbaum JD, Glabe CG, Protter AA, Martins RN, Ehrlich ME, Petsko GA, Yue Z, Gandy S.

Mol Psychiatry. 2013 Aug;18(8):889-97. doi: 10.1038/mp.2012.106. Epub 2012 Jul 31.

15.

The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK).

Davies CW, Chaney J, Korbel G, Ringe D, Petsko GA, Ploegh H, Das C.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3900-4. doi: 10.1016/j.bmcl.2012.04.124. Epub 2012 May 4.

16.

A soluble α-synuclein construct forms a dynamic tetramer.

Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LT, Liao J, Auclair JR, Johnson D, Landeru A, Simorellis AK, Ju S, Cookson MR, Asturias FJ, Agar JN, Webb BN, Kang C, Ringe D, Petsko GA, Pochapsky TC, Hoang QQ.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17797-802. doi: 10.1073/pnas.1113260108. Epub 2011 Oct 17.

17.

Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis.

Bosco DA, LaVoie MJ, Petsko GA, Ringe D.

Cold Spring Harb Perspect Biol. 2011 Oct 1;3(10):a007500. doi: 10.1101/cshperspect.a007500. Review.

18.

Time-of-flight neutron diffraction study of bovine γ-chymotrypsin at the Protein Crystallography Station.

Lazar LM, Fisher SZ, Moulin AG, Kovalevsky A, Novak WR, Langan P, Petsko GA, Ringe D.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):587-90. doi: 10.1107/S1744309111009341. Epub 2011 Apr 27.

19.

A yeast model of FUS/TLS-dependent cytotoxicity.

Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH Jr, Lindquist S, Ringe D, Petsko GA.

PLoS Biol. 2011 Apr;9(4):e1001052. doi: 10.1371/journal.pbio.1001052. Epub 2011 Apr 26.

20.

Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida.

Brodkin HR, Novak WR, Milne AC, D'Aquino JA, Karabacak NM, Goldberg IG, Agar JN, Payne MS, Petsko GA, Ondrechen MJ, Ringe D.

Biochemistry. 2011 Jun 7;50(22):4923-35. doi: 10.1021/bi101761e. Epub 2011 May 12.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk