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Results: 1 to 20 of 148

1.

Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial.

Kordes S, Pollak MN, Zwinderman AH, Mathôt RA, Weterman MJ, Beeker A, Punt CJ, Richel DJ, Wilmink JW.

Lancet Oncol. 2015 Jul;16(7):839-47. doi: 10.1016/S1470-2045(15)00027-3. Epub 2015 Jun 8.

PMID:
26067687
2.

Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer.

Kordes S, Klümpen HJ, Weterman MJ, Schellens JH, Richel DJ, Wilmink JW.

Cancer Chemother Pharmacol. 2015 Jun;75(6):1135-41. doi: 10.1007/s00280-015-2730-y. Epub 2015 Mar 31.

3.

Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme.

van Linde ME, Verhoeff JJ, Richel DJ, van Furth WR, Reijneveld JC, Verheul HM, Stalpers LJ.

Oncologist. 2015 Feb;20(2):107-8. doi: 10.1634/theoncologist.2014-0418. Epub 2015 Jan 12.

4.

Preoperative chemoradiation therapy in combination with panitumumab for patients with resectable esophageal cancer: the PACT study.

Kordes S, van Berge Henegouwen MI, Hulshof MC, Bergman JJ, van der Vliet HJ, Kapiteijn E, van Laarhoven HW, Richel DJ, Klinkenbijl JH, Meijer SL, Wilmink JW.

Int J Radiat Oncol Biol Phys. 2014 Sep 1;90(1):190-6. doi: 10.1016/j.ijrobp.2014.05.022.

PMID:
25195993
5.

Protease-activated receptor 2 suppresses lymphangiogenesis and subsequent lymph node metastasis in a murine pancreatic cancer model.

Shi K, Queiroz KC, Roelofs JJ, van Noesel CJ, Richel DJ, Spek CA.

J Pathol. 2014 Nov;234(3):398-409. doi: 10.1002/path.4411. Epub 2014 Sep 12.

PMID:
25065357
6.

Preoperative chemoradiotherapy in locally advanced gastric cancer, a phase I/II feasibility and efficacy study.

Trip AK, Poppema BJ, van Berge Henegouwen MI, Siemerink E, Beukema JC, Verheij M, Plukker JT, Richel DJ, Hulshof MC, van Sandick JW, Cats A, Jansen EP, Hospers GA.

Radiother Oncol. 2014 Aug;112(2):284-8. doi: 10.1016/j.radonc.2014.05.003. Epub 2014 May 22.

PMID:
24856116
7.

Protease-activated receptor-1 drives pancreatic cancer progression and chemoresistance.

Queiroz KC, Shi K, Duitman J, Aberson HL, Wilmink JW, van Noesel CJ, Richel DJ, Spek CA.

Int J Cancer. 2014 Nov 15;135(10):2294-304. doi: 10.1002/ijc.28726. Epub 2014 Jun 19.

PMID:
24436106
8.

Patterns of recurrence after surgery alone versus preoperative chemoradiotherapy and surgery in the CROSS trials.

Oppedijk V, van der Gaast A, van Lanschot JJ, van Hagen P, van Os R, van Rij CM, van der Sangen MJ, Beukema JC, Rütten H, Spruit PH, Reinders JG, Richel DJ, van Berge Henegouwen MI, Hulshof MC.

J Clin Oncol. 2014 Feb 10;32(5):385-91. doi: 10.1200/JCO.2013.51.2186. Epub 2014 Jan 13.

9.

Protease-activated receptor-2 induces migration of pancreatic cancer cells in an extracellular ATP-dependent manner.

Shi K, Queiroz KC, Stap J, Richel DJ, Spek CA.

J Thromb Haemost. 2013 Oct;11(10):1892-902. doi: 10.1111/jth.12361.

PMID:
23899344
10.

Tumour-stroma interactions in pancreatic ductal adenocarcinoma: rationale and current evidence for new therapeutic strategies.

Heinemann V, Reni M, Ychou M, Richel DJ, Macarulla T, Ducreux M.

Cancer Treat Rev. 2014 Feb;40(1):118-28. doi: 10.1016/j.ctrv.2013.04.004. Epub 2013 Jul 9. Review.

PMID:
23849556
11.

Neoadjuvant chemoradiotherapy followed by esophagectomy does not increase morbidity in patients over 70.

Blom RL, van Heijl M, Klinkenbijl JH, Bergman JJ, Wilmink JW, Richel DJ, Hulshof MC, Reitsma JB, Busch OR, van Berge Henegouwen MI.

Dis Esophagus. 2013 Jul;26(5):510-6. doi: 10.1111/j.1442-2050.2012.01394.x. Epub 2012 Aug 23.

PMID:
22925313
12.

Preoperative chemoradiotherapy for esophageal or junctional cancer.

van Hagen P, Hulshof MC, van Lanschot JJ, Steyerberg EW, van Berge Henegouwen MI, Wijnhoven BP, Richel DJ, Nieuwenhuijzen GA, Hospers GA, Bonenkamp JJ, Cuesta MA, Blaisse RJ, Busch OR, ten Kate FJ, Creemers GJ, Punt CJ, Plukker JT, Verheul HM, Spillenaar Bilgen EJ, van Dekken H, van der Sangen MJ, Rozema T, Biermann K, Beukema JC, Piet AH, van Rij CM, Reinders JG, Tilanus HW, van der Gaast A; CROSS Group.

N Engl J Med. 2012 May 31;366(22):2074-84. doi: 10.1056/NEJMoa1112088.

13.

Coagulation activation and microparticle-associated coagulant activity in cancer patients. An exploratory prospective study.

van Doormaal F, Kleinjan A, Berckmans RJ, Mackman N, Manly D, Kamphuisen PW, Richel DJ, Büller HR, Sturk A, Nieuwland R.

Thromb Haemost. 2012 Jul;108(1):160-5. doi: 10.1160/TH12-02-0099. Epub 2012 Apr 26.

PMID:
22535219
14.

A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer.

Kordes S, Richel DJ, Klümpen HJ, Weterman MJ, Stevens AJ, Wilmink JW.

Invest New Drugs. 2013 Feb;31(1):85-91. doi: 10.1007/s10637-012-9802-1. Epub 2012 Feb 25.

15.

Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.

de Jong JH, Rodermond HM, Zimberlin CD, Lascano V, De Sousa E Melo F, Richel DJ, Medema JP, Vermeulen L.

Sci Rep. 2012;2:271. doi: 10.1038/srep00271. Epub 2012 Feb 15.

16.

The developing cancer stem-cell model: clinical challenges and opportunities.

Vermeulen L, de Sousa e Melo F, Richel DJ, Medema JP.

Lancet Oncol. 2012 Feb;13(2):e83-9. doi: 10.1016/S1470-2045(11)70257-1. Review.

PMID:
22300863
17.

Validation of serum amyloid α as an independent biomarker for progression-free and overall survival in metastatic renal cell cancer patients.

Vermaat JS, Gerritse FL, van der Veldt AA, Roessingh WM, Niers TM, Oosting SF, Sleijfer S, Roodhart JM, Beijnen JH, Schellens JH, Gietema JA, Boven E, Richel DJ, Haanen JB, Voest EE.

Eur Urol. 2012 Oct;62(4):685-95. doi: 10.1016/j.eururo.2012.01.020. Epub 2012 Jan 23.

PMID:
22285764
18.

5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.

Baan B, Dihal AA, Hoff E, Bos CL, Voorneveld PW, Koelink PJ, Wildenberg ME, Muncan V, Heijmans J, Verspaget HW, Richel DJ, Hardwick JC, Hommes DW, Peppelenbosch MP, van den Brink GR.

Gut. 2012 Dec;61(12):1708-15. doi: 10.1136/gutjnl-2011-301626. Epub 2011 Dec 20.

PMID:
22187071
19.

Cardiac safety of adjuvant pegylated liposomal doxorubicin with concurrent trastuzumab: a randomized phase II trial.

Rayson D, Suter TM, Jackisch C, van der Vegt S, Bermejo B, van den Bosch J, Vivanco GL, van Gent AM, Wildiers H, Torres A, Provencher L, Temizkan M, Chirgwin J, Canon JL, Ferrandina G, Srinivasan S, Zhang L, Richel DJ.

Ann Oncol. 2012 Jul;23(7):1780-8. doi: 10.1093/annonc/mdr519. Epub 2011 Nov 4.

20.

Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.

de Sousa E Melo F, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, Tuynman JB, Prasetyanti PR, Fessler E, van den Bergh SP, Rodermond H, Dekker E, van der Loos CM, Pals ST, van de Vijver MJ, Versteeg R, Richel DJ, Vermeulen L, Medema JP.

Cell Stem Cell. 2011 Nov 4;9(5):476-85. doi: 10.1016/j.stem.2011.10.008.

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