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Resistin-like molecule beta acts as a mitogenic factor in hypoxic pulmonary hypertension via the Ca(2+)-dependent PI3K/Akt/mTOR and PKC/MAPK signaling pathways.
Tian H, Liu L, Wu Y, Wang R, Jiang Y, Hu R, Zhu L, Li L, Fang Y, Yang C, Ji L, Liu G, Dai A. Tian H, et al. Respir Res. 2021 Jan 6;22(1):8. doi: 10.1186/s12931-020-01598-4. Respir Res. 2021. PMID: 33407472 Free PMC article.
BACKGROUND: Pulmonary arterial smooth muscle cell (PASMC) proliferation plays a crucial role in hypoxia-induced pulmonary hypertension (HPH). Previous studies have found that resistin-like molecule beta (RELM-beta) is upregulated de novo in response to …
BACKGROUND: Pulmonary arterial smooth muscle cell (PASMC) proliferation plays a crucial role in hypoxia-induced pulmonary hypertension (HPH) …
The Mechanisms of Resistin-Like Molecule-beta-Mediated Airway Inflammation in Chronic Obstructive Pulmonary Disease via Autophagy.
Che L, Xie Z, Chen G, Zhang W, Xia T, Lin J, Luo W, Chen L, Yin W, Cai X, Liu S. Che L, et al. J Inflamm Res. 2023 Aug 31;16:3853-3870. doi: 10.2147/JIR.S403517. eCollection 2023. J Inflamm Res. 2023. PMID: 37671130 Free PMC article.
Autophagy is an essential process in the cellular material metabolic cycle, and a family of resistant vegetative molecules may be involved in the COPD autophagic process. In this study, we investigated the mechanism of resistin-like molecule beta (RELM …
Autophagy is an essential process in the cellular material metabolic cycle, and a family of resistant vegetative molecules may be involved i …
Resistin-like molecule beta augments phenotypic modulation of human aortic smooth muscle cell triggered by high glucose.
Wang Y, Zhang Y, Gao X, Qian J, Yang J, Sun W, Wang H, Yang Y. Wang Y, et al. Endocr J. 2021 Apr 28;68(4):461-468. doi: 10.1507/endocrj.EJ20-0343. Epub 2021 Jan 13. Endocr J. 2021. PMID: 33441498 Free article.
Vascular muscle cells (VSMCs) participate in the pathophysiology of atherosclerosis. Resistin-like molecule beta (Relmbeta) contributes to atherosclerosis development by activating macrophage. ...
Vascular muscle cells (VSMCs) participate in the pathophysiology of atherosclerosis. Resistin-like molecule beta …
Retracted: Resistin-Like Molecule Beta (RELM-beta) Regulates Proliferation of Human Diabetic Nephropathy Mesangial Cells via Mitogen-Activated Protein Kinases (MAPK) Signaling Pathway.
Wang YQ, Fan CC, Chen BP, Shi J. Wang YQ, et al. Med Sci Monit. 2022 Mar 3;28:e936542. doi: 10.12659/MSM.936542. Med Sci Monit. 2022. PMID: 35236816 Free PMC article.
Reference: Yun-Qian Wang, Cong-Cong Fan, Bao-Ping Chen, Jun Shi. Resistin-Like Molecule Beta (RELM-ss) Regulates Proliferation of Human Diabetic Nephropathy Mesangial Cells via Mitogen-Activated Protein Kinases (MAPK) Signaling Pathway. ...
Reference: Yun-Qian Wang, Cong-Cong Fan, Bao-Ping Chen, Jun Shi. Resistin-Like Molecule Beta (RELM-ss) Regulates …
Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.
Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA. Angelini DJ, et al. Am J Respir Cell Mol Biol. 2009 Nov;41(5):553-61. doi: 10.1165/rcmb.2008-0271OC. Epub 2009 Feb 27. Am J Respir Cell Mol Biol. 2009. PMID: 19251945 Free PMC article.
We have demonstrated that HIMF has mitogenic, angiogenic, vasoconstrictive, inflammatory, and chemokine-like properties, all of which are associated with vascular remodeling in the lung. Here, we demonstrate that the human homolog of HIMF, resistin-like molecule (RE …
We have demonstrated that HIMF has mitogenic, angiogenic, vasoconstrictive, inflammatory, and chemokine-like properties, all of which are as …
Resistin-like molecule-beta is a human airway remodelling mediator.
Fang C, Meng Q, Wu H, Eid G, Zhang G, Zhang X, Yang S, Huang K, Lee TH, Corrigan CJ, Ying S. Fang C, et al. Eur Respir J. 2012 Feb;39(2):458-66. doi: 10.1183/09031936.00107811. Epub 2011 Aug 4. Eur Respir J. 2012. PMID: 21828035 Free article.
Though implicated in vascular remodelling, a role for the resistin-like molecule (RELM)-beta in human airway remodelling remains unexplored. ...
Though implicated in vascular remodelling, a role for the resistin-like molecule (RELM)-beta in human airway remodelling remai …
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility.
Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rothenberg ME. Hogan SP, et al. J Allergy Clin Immunol. 2006 Jul;118(1):257-68. doi: 10.1016/j.jaci.2006.04.039. J Allergy Clin Immunol. 2006. PMID: 16815164 Free PMC article.
BACKGROUND: Resistin-like molecule (RELM) beta is a cysteine-rich cytokine expressed in the gastrointestinal tract and implicated in insulin resistance and gastrointestinal nematode immunity; however, its function primarily remains an enigma. ...
BACKGROUND: Resistin-like molecule (RELM) beta is a cysteine-rich cytokine expressed in the gastrointestinal tract and implica …
Resistin-like molecule-beta is induced following bronchoconstriction of asthmatic airways.
Grainge C, Dulay V, Ward J, Sammut D, Davies E, Green B, Lau L, Cottey L, Haitchi HM, Davies DE, Howarth PH. Grainge C, et al. Respirology. 2012 Oct;17(7):1094-100. doi: 10.1111/j.1440-1843.2012.02215.x. Respirology. 2012. PMID: 22758223
BACKGROUND AND OBJECTIVE: Resistin-like molecule-beta (RELM-beta) is a necessary and sufficient stimulus for airway remodelling in animal models of asthma, but until recently, its role in human disease had not been investigated. ...
BACKGROUND AND OBJECTIVE: Resistin-like molecule-beta (RELM-beta) is a necessary and sufficient stimulus for air …
Resistin-like molecule beta, a colonic epithelial protein, exhibits antimicrobial activity against Staphylococcus aureus including methicillin-resistant strains.
Watanabe K, Itoh K, Park SH, Kaku M, Ishii K, Sasano H, Naitoh T, Unno M, Fukushima K. Watanabe K, et al. Surg Today. 2020 Aug;50(8):920-930. doi: 10.1007/s00595-020-01974-z. Epub 2020 Feb 15. Surg Today. 2020. PMID: 32062787
PURPOSE: Resistin-like molecule beta (RELMbeta) is a small cysteine-rich protein secreted by colonic epithelial cells. ...
PURPOSE: Resistin-like molecule beta (RELMbeta) is a small cysteine-rich protein secreted by colonic epithelial …
Resistin-like molecule-beta inhibits SGLT-1 activity and enhances GLUT2-dependent jejunal glucose transport.
Krimi RB, Letteron P, Chedid P, Nazaret C, Ducroc R, Marie JC. Krimi RB, et al. Diabetes. 2009 Sep;58(9):2032-8. doi: 10.2337/db08-1786. Epub 2009 Jun 5. Diabetes. 2009. PMID: 19502416 Free PMC article.
OBJECTIVE: An increased expression of RELM-beta (resistin-like molecule-beta), a gut-derived hormone, is observed in animal models of insulin resistance/obesity and intestinal inflammation. ...
OBJECTIVE: An increased expression of RELM-beta (resistin-like molecule-beta), a gut-derived hormone, is observe …
76 results