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Results: 18


Model-based analysis of HER activation in cells co-expressing EGFR, HER2 and HER3.

Shankaran H, Zhang Y, Tan Y, Resat H.

PLoS Comput Biol. 2013;9(8):e1003201. doi: 10.1371/journal.pcbi.1003201. Epub 2013 Aug 22.


Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.

Shankaran H, Zhang Y, Chrisler WB, Ewald JA, Wiley HS, Resat H.

Mol Biosyst. 2012 Nov;8(11):2868-82. doi: 10.1039/c2mb25190f. Epub 2012 Sep 5.


An adaptive coarse graining method for signal transduction in three dimensions.

Archuleta MN, McDermott JE, Edwards JS, Resat H.

Fundam Inform. 2012;118(4). doi: 10.3233/FI-2012-720.


Spatial aspects in biological system simulations.

Resat H, Costa MN, Shankaran H.

Methods Enzymol. 2011;487:485-511. doi: 10.1016/B978-0-12-381270-4.00017-2.


Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor.

Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, Opresko LK, Wiley HS.

Mol Syst Biol. 2009;5:332. doi: 10.1038/msb.2009.90. Epub 2009 Dec 1.


HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.

Zhang Y, Opresko L, Shankaran H, Chrisler WB, Wiley HS, Resat H.

BMC Cell Biol. 2009 Oct 31;10:78. doi: 10.1186/1471-2121-10-78.


Kinetic modeling of biological systems.

Resat H, Petzold L, Pettigrew MF.

Methods Mol Biol. 2009;541:311-35. doi: 10.1007/978-1-59745-243-4_14. Review.


System theoretical investigation of human epidermal growth factor receptor-mediated signalling.

Zhang Y, Shankaran H, Opresko L, Resat H.

IET Syst Biol. 2008 Sep;2(5):273-84. doi: 10.1049/iet-syb:20080116.


Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking.

Shankaran H, Zhang Y, Opresko L, Resat H.

Biochem Biophys Res Commun. 2008 Jun 27;371(2):220-4. doi: 10.1016/j.bbrc.2008.04.043. Epub 2008 Apr 18.


A domain-based approach to predict protein-protein interactions.

Singhal M, Resat H.

BMC Bioinformatics. 2007 Jun 13;8:199.


Cell surface receptors for signal transduction and ligand transport: a design principles study.

Shankaran H, Resat H, Wiley HS.

PLoS Comput Biol. 2007 Jun;3(6):e101. Epub 2007 Apr 20. Review.


Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response.

Shankaran H, Wiley HS, Resat H.

Biophys J. 2006 Jun 1;90(11):3993-4009. Epub 2006 Mar 13.


An integrated model of epidermal growth factor receptor trafficking and signal transduction.

Resat H, Ewald JA, Dixon DA, Wiley HS.

Biophys J. 2003 Aug;85(2):730-43.


The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP.

Resat H, Straatsma TP, Dixon DA, Miller JH.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6033-8.


Enzyme-inhibitor association thermodynamics: explicit and continuum solvent studies.

Resat H, Marrone TJ, McCammon JA.

Biophys J. 1997 Feb;72(2 Pt 1):522-32.

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