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Results: 1 to 20 of 30

1.

Model-based analysis of HER activation in cells co-expressing EGFR, HER2 and HER3.

Shankaran H, Zhang Y, Tan Y, Resat H.

PLoS Comput Biol. 2013;9(8):e1003201. doi: 10.1371/journal.pcbi.1003201. Epub 2013 Aug 22.

PMID:
23990774
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.

Shankaran H, Zhang Y, Chrisler WB, Ewald JA, Wiley HS, Resat H.

Mol Biosyst. 2012 Nov;8(11):2868-82. doi: 10.1039/c2mb25190f. Epub 2012 Sep 5.

PMID:
22952062
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

An adaptive coarse graining method for signal transduction in three dimensions.

Archuleta MN, McDermott JE, Edwards JS, Resat H.

Fundam Inform. 2012;118(4). doi: 10.3233/FI-2012-720.

PMID:
24357890
[PubMed]
Free PMC Article
4.

Modeling microbial dynamics in heterogeneous environments: growth on soil carbon sources.

Resat H, Bailey V, McCue LA, Konopka A.

Microb Ecol. 2012 May;63(4):883-97. doi: 10.1007/s00248-011-9965-x. Epub 2011 Dec 23.

PMID:
22193925
[PubMed - indexed for MEDLINE]
5.

Spatial aspects in biological system simulations.

Resat H, Costa MN, Shankaran H.

Methods Enzymol. 2011;487:485-511. doi: 10.1016/B978-0-12-381270-4.00017-2.

PMID:
21187236
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor.

Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, Opresko LK, Wiley HS.

Mol Syst Biol. 2009;5:332. doi: 10.1038/msb.2009.90. Epub 2009 Dec 1.

PMID:
19953086
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.

Zhang Y, Opresko L, Shankaran H, Chrisler WB, Wiley HS, Resat H.

BMC Cell Biol. 2009 Oct 31;10:78. doi: 10.1186/1471-2121-10-78.

PMID:
19878579
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Kinetic modeling of biological systems.

Resat H, Petzold L, Pettigrew MF.

Methods Mol Biol. 2009;541:311-35. doi: 10.1007/978-1-59745-243-4_14. Review.

PMID:
19381542
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

System theoretical investigation of human epidermal growth factor receptor-mediated signalling.

Zhang Y, Shankaran H, Opresko L, Resat H.

IET Syst Biol. 2008 Sep;2(5):273-84. doi: 10.1049/iet-syb:20080116.

PMID:
19045822
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking.

Shankaran H, Zhang Y, Opresko L, Resat H.

Biochem Biophys Res Commun. 2008 Jun 27;371(2):220-4. doi: 10.1016/j.bbrc.2008.04.043. Epub 2008 Apr 18.

PMID:
18424261
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Receptor downregulation and desensitization enhance the information processing ability of signalling receptors.

Shankaran H, Wiley HS, Resat H.

BMC Syst Biol. 2007 Nov 9;1:48.

PMID:
17996096
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A domain-based approach to predict protein-protein interactions.

Singhal M, Resat H.

BMC Bioinformatics. 2007 Jun 13;8:199.

PMID:
17567909
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cell surface receptors for signal transduction and ligand transport: a design principles study.

Shankaran H, Resat H, Wiley HS.

PLoS Comput Biol. 2007 Jun;3(6):e101. Epub 2007 Apr 20. Review.

PMID:
17542642
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Multinomial tau-leaping method for stochastic kinetic simulations.

Pettigrew MF, Resat H.

J Chem Phys. 2007 Feb 28;126(8):084101.

PMID:
17343434
[PubMed - indexed for MEDLINE]
15.

Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response.

Shankaran H, Wiley HS, Resat H.

Biophys J. 2006 Jun 1;90(11):3993-4009. Epub 2006 Mar 13.

PMID:
16533841
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Modeling signal transduction networks: a comparison of two stochastic kinetic simulation algorithms.

Pettigrew MF, Resat H.

J Chem Phys. 2005 Sep 15;123(11):114707.

PMID:
16392583
[PubMed - indexed for MEDLINE]
17.

Combining microarray and genomic data to predict DNA binding motifs.

Mao L, Mackenzie C, Roh JH, Eraso JM, Kaplan S, Resat H.

Microbiology. 2005 Oct;151(Pt 10):3197-213.

PMID:
16207904
[PubMed - indexed for MEDLINE]
Free Article
18.

A model of cytokine shedding induced by low doses of gamma radiation.

Miller JH, Zheng F, Jin S, Opresko LK, Wiley HS, Resat H.

Radiat Res. 2005 Mar;163(3):337-42.

PMID:
15733041
[PubMed - indexed for MEDLINE]
19.

Probabilistic representation of gene regulatory networks.

Mao L, Resat H.

Bioinformatics. 2004 Sep 22;20(14):2258-69. Epub 2004 Apr 8.

PMID:
15073019
[PubMed - indexed for MEDLINE]
Free Article
20.

An integrated model of epidermal growth factor receptor trafficking and signal transduction.

Resat H, Ewald JA, Dixon DA, Wiley HS.

Biophys J. 2003 Aug;85(2):730-43.

PMID:
12885624
[PubMed - indexed for MEDLINE]
Free PMC Article

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