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Results: 20

1.

Live multicellular tumor spheroid models for high-content imaging and screening in cancer drug discovery.

Reid BG, Jerjian T, Patel P, Zhou Q, Yoo BH, Kabos P, Sartorius CA, Labarbera DV.

Curr Chem Genom Transl Med. 2014 Feb 7;8(Suppl 1):27-35. doi: 10.2174/2213988501408010027. eCollection 2014.

2.

A small-molecule inhibitor of hepatitis C virus infectivity.

Bush CO, Pokrovskii MV, Saito R, Morganelli P, Canales E, Clarke MO, Lazerwith SE, Golde J, Reid BG, Babaoglu K, Pagratis N, Zhong W, Delaney WE 4th, Paulson MS, Beran RK.

Antimicrob Agents Chemother. 2014;58(1):386-96. doi: 10.1128/AAC.02083-13. Epub 2013 Oct 28.

3.

BET acetyl-lysine binding proteins control pathological cardiac hypertrophy.

Spiltoir JI, Stratton MS, Cavasin MA, Demos-Davies K, Reid BG, Qi J, Bradner JE, McKinsey TA.

J Mol Cell Cardiol. 2013 Oct;63:175-9. doi: 10.1016/j.yjmcc.2013.07.017. Epub 2013 Aug 9.

4.

Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.

Ferguson BS, Harrison BC, Jeong MY, Reid BG, Wempe MF, Wagner FF, Holson EB, McKinsey TA.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9806-11. doi: 10.1073/pnas.1301509110. Epub 2013 May 29.

5.

The multicellular tumor spheroid model for high-throughput cancer drug discovery.

LaBarbera DV, Reid BG, Yoo BH.

Expert Opin Drug Discov. 2012 Sep;7(9):819-30. doi: 10.1517/17460441.2012.708334. Epub 2012 Jul 12. Review.

PMID:
22788761
6.

A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer.

Yoo BH, Axlund SD, Kabos P, Reid BG, Schaack J, Sartorius CA, LaBarbera DV.

J Biomol Screen. 2012 Oct;17(9):1211-20. Epub 2012 Jun 29.

7.

Neoamphimedine circumvents metnase-enhanced DNA topoisomerase IIα activity through ATP-competitive inhibition.

Ponder J, Yoo BH, Abraham AD, Li Q, Ashley AK, Amerin CL, Zhou Q, Reid BG, Reigan P, Hromas R, Nickoloff JA, LaBarbera DV.

Mar Drugs. 2011;9(11):2397-408. doi: 10.3390/md9112397. Epub 2011 Nov 18.

8.

Screening and identification of a novel class of TGF-β type 1 receptor kinase inhibitor.

Huynh QK, Wise SJ, Koch KA, Castonguay LA, Reid BG, Pagratis EE, Koditek D, Glascock CB, Pitts KR, Turner BA, Liu X, Hung M, Han B, Pagratis N.

J Biomol Screen. 2011 Aug;16(7):724-33. doi: 10.1177/1087057111405846. Epub 2011 Apr 26.

PMID:
21521800
9.

Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.

Monovich L, Koch KA, Burgis R, Osimboni E, Mann T, Wall D, Gao J, Feng Y, Vega RB, Turner BA, Hood DB, Law A, Papst PJ, Koditek D, Chapo JA, Reid BG, Melvin LS, Pagratis NC, McKinsey TA.

Biochim Biophys Acta. 2009 May;1789(5):422-31. doi: 10.1016/j.bbagrm.2009.04.001. Epub 2009 May 3.

PMID:
19414071
10.

High-throughput determination of mode of inhibition in lead identification and optimization.

Wei M, Wynn R, Hollis G, Liao B, Margulis A, Reid BG, Klabe R, Liu PC, Becker-Pasha M, Rupar M, Burn TC, McCall DE, Li Y.

J Biomol Screen. 2007 Mar;12(2):220-8.

PMID:
17351185
11.

Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.

Ala PJ, Gonneville L, Hillman MC, Becker-Pasha M, Wei M, Reid BG, Klabe R, Yue EW, Wayland B, Douty B, Polam P, Wasserman Z, Bower M, Combs AP, Burn TC, Hollis GF, Wynn R.

J Biol Chem. 2006 Oct 27;281(43):32784-95. Epub 2006 Aug 17.

12.

Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.

Combs AP, Yue EW, Bower M, Ala PJ, Wayland B, Douty B, Takvorian A, Polam P, Wasserman Z, Zhu W, Crawley ML, Pruitt J, Sparks R, Glass B, Modi D, McLaughlin E, Bostrom L, Li M, Galya L, Blom K, Hillman M, Gonneville L, Reid BG, Wei M, Becker-Pasha M, Klabe R, Huber R, Li Y, Hollis G, Burn TC, Wynn R, Liu P, Metcalf B.

J Med Chem. 2005 Oct 20;48(21):6544-8.

PMID:
16220970
13.

Roles of the N-domains of the ClpA unfoldase in binding substrate proteins and in stable complex formation with the ClpP protease.

Hinnerwisch J, Reid BG, Fenton WA, Horwich AL.

J Biol Chem. 2005 Dec 9;280(49):40838-44. Epub 2005 Oct 5.

14.

ClpS, a substrate modulator of the ClpAP machine.

Dougan DA, Reid BG, Horwich AL, Bukau B.

Mol Cell. 2002 Mar;9(3):673-83.

PMID:
11931773
15.

ClpA mediates directional translocation of substrate proteins into the ClpP protease.

Reid BG, Fenton WA, Horwich AL, Weber-Ban EU.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3768-72. Epub 2001 Mar 20.

16.

Global unfolding of a substrate protein by the Hsp100 chaperone ClpA.

Weber-Ban EU, Reid BG, Miranker AD, Horwich AL.

Nature. 1999 Sep 2;401(6748):90-3.

PMID:
10485712
17.

Chromophore formation in green fluorescent protein.

Reid BG, Flynn GC.

Biochemistry. 1997 Jun 3;36(22):6786-91.

PMID:
9184161
18.

GroEL binds to and unfolds rhodanese posttranslationally.

Reid BG, Flynn GC.

J Biol Chem. 1996 Mar 22;271(12):7212-7.

19.

Natural history of acute pancreatitis. A long-term study.

Reid BG, Kune GA.

Med J Aust. 1980 Nov 15;2(10):555-8.

PMID:
7464600
20.

Accuracy in diagnosis of acute pancreatitis.

Reid BG, Kune GA.

Med J Aust. 1978 Jun 3;1(11):583-7.

PMID:
683071
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