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Items: 1 to 20 of 53


Stem cell research in Latin America: update, challenges and opportunities in a priority research area.

Palma V, Pitossi FJ, Rehen SK, Touriño C, Velasco I.

Regen Med. 2015 Sep;10(6):785-98. doi: 10.2217/rme.15.44. Epub 2015 Oct 6.


Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson's disease.

Acquarone M, de Melo TM, Meireles F, Brito-Moreira J, Oliveira G, Ferreira ST, Castro NG, Tovar-Moll F, Houzel JC, Rehen SK.

Front Cell Neurosci. 2015 Apr 8;9:97. doi: 10.3389/fncel.2015.00097. eCollection 2015.


Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains.

Bushman DM, Kaeser GE, Siddoway B, Westra JW, Rivera RR, Rehen SK, Yung YC, Chun J.

Elife. 2015 Feb 4;4. doi: 10.7554/eLife.05116.


Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen species.

Campos PB, Paulsen BS, Rehen SK.

Front Aging Neurosci. 2014 Oct 27;6:292. doi: 10.3389/fnagi.2014.00292. eCollection 2014. Review.


Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy.

Biasoli D, Sobrinho MF, da Fonseca AC, de Matos DG, Romão L, de Moraes Maciel R, Rehen SK, Moura-Neto V, Borges HL, Lima FR.

Oncogenesis. 2014 Oct 20;3:e123. doi: 10.1038/oncsis.2014.36.


LPA-primed astrocytes induce axonal outgrowth of cortical progenitors by activating PKA signaling pathways and modulating extracellular matrix proteins.

Spohr TC, Dezonne RS, Rehen SK, Gomes FC.

Front Cell Neurosci. 2014 Sep 25;8:296. doi: 10.3389/fncel.2014.00296. eCollection 2014.


Valproate reverts zinc and potassium imbalance in schizophrenia-derived reprogrammed cells.

Paulsen Bda S, Cardoso SC, Stelling MP, Cadilhe DV, Rehen SK.

Schizophr Res. 2014 Apr;154(1-3):30-5. doi: 10.1016/j.schres.2014.02.007. Epub 2014 Mar 1.


2,4-Dinitrophenol induces neural differentiation of murine embryonic stem cells.

Freitas-Correa L, Lourenco MV, Acquarone M, da Costa RF, Galina A, Rehen SK, Ferreira ST.

Stem Cell Res. 2013 Nov;11(3):1407-16. doi: 10.1016/j.scr.2013.09.016. Epub 2013 Oct 6.


Aneuploid cells are differentially susceptible to caspase-mediated death during embryonic cerebral cortical development.

Peterson SE, Yang AH, Bushman DM, Westra JW, Yung YC, Barral S, Mutoh T, Rehen SK, Chun J.

J Neurosci. 2012 Nov 14;32(46):16213-22. doi: 10.1523/JNEUROSCI.3706-12.2012.


Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders.

Paulsen Bda S, da Silveira MS, Galina A, Rehen SK.

Arch Biochem Biophys. 2013 Jun;534(1-2):3-10. doi: 10.1016/ Epub 2012 Oct 27. Review.


Matrix-bound heparan sulfate is essential for the growth and pluripotency of human embryonic stem cells.

Stelling MP, Lages YM, Tovar AM, Mourão PA, Rehen SK.

Glycobiology. 2013 Mar;23(3):337-45. doi: 10.1093/glycob/cws133. Epub 2012 Sep 22.


Implications of aneuploidy for stem cell biology and brain therapeutics.

Devalle S, Sartore RC, Paulsen BS, Borges HL, Martins RA, Rehen SK.

Front Cell Neurosci. 2012 Sep 5;6:36. doi: 10.3389/fncel.2012.00036. eCollection 2012.


Xeno-free production of human embryonic stem cells in stirred microcarrier systems using a novel animal/human-component-free medium.

Marinho PA, Vareschini DT, Gomes IC, Paulsen Bda S, Furtado DR, Castilho Ldos R, Rehen SK.

Tissue Eng Part C Methods. 2013 Feb;19(2):146-55. doi: 10.1089/ten.TEC.2012.0141. Epub 2012 Oct 16.


Sphingosine 1-phosphate-primed astrocytes enhance differentiation of neuronal progenitor cells.

Spohr TC, Dezonne RS, Nones J, Dos Santos Souza C, Einicker-Lamas M, Gomes FC, Rehen SK.

J Neurosci Res. 2012 Oct;90(10):1892-902. doi: 10.1002/jnr.23076. Epub 2012 May 15.


Cycle arrest and aneuploidy induced by zidovudine in murine embryonic stem cells.

Campos PB, Sartore RC, Ramalho BL, Costa ES, Rehen SK.

Mutagenesis. 2012 Jul;27(4):431-6. doi: 10.1093/mutage/ger093. Epub 2012 Jan 4.


Synchrotron radiation X-ray microfluorescence reveals polarized distribution of atomic elements during differentiation of pluripotent stem cells.

Cardoso SC, Stelling MP, Paulsen BS, Rehen SK.

PLoS One. 2011;6(12):e29244. doi: 10.1371/journal.pone.0029244. Epub 2011 Dec 16.


Dynamic expression of synemin isoforms in mouse embryonic stem cells and neural derivatives.

de Souza Martins SC, Agbulut O, Diguet N, Larcher JC, Paulsen BS, Rehen SK, Moura-Neto V, Paulin D, Li Z, Xue Z.

BMC Cell Biol. 2011 Nov 23;12:51. doi: 10.1186/1471-2121-12-51.


Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient.

Paulsen Bda S, de Moraes Maciel R, Galina A, Souza da Silveira M, dos Santos Souza C, Drummond H, Nascimento Pozzatto E, Silva H Jr, Chicaybam L, Massuda R, Setti-Perdigão P, Bonamino M, Belmonte-de-Abreu PS, Castro NG, Brentani H, Rehen SK.

Cell Transplant. 2012;21(7):1547-59.


Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy.

Peterson SE, Westra JW, Rehen SK, Young H, Bushman DM, Paczkowski CM, Yung YC, Lynch CL, Tran HT, Nickey KS, Wang YC, Laurent LC, Loring JF, Carpenter MK, Chun J.

PLoS One. 2011;6(8):e23018. doi: 10.1371/journal.pone.0023018. Epub 2011 Aug 16.


Astrocytes treated by lysophosphatidic acid induce axonal outgrowth of cortical progenitors through extracellular matrix protein and epidermal growth factor signaling pathway.

E Spohr TC, Dezonne RS, Rehen SK, Gomes FC.

J Neurochem. 2011 Oct;119(1):113-23. doi: 10.1111/j.1471-4159.2011.07421.x. Epub 2011 Sep 1.

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