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Items: 1 to 20 of 140

1.

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy.

Yarla NS, Bishayee A, Sethi G, Reddanna P, Kalle AM, Dhananjaya BL, Dowluru KS, Chintala R, Duddukuri GR.

Semin Cancer Biol. 2016 Feb 4. pii: S1044-579X(16)30003-7. doi: 10.1016/j.semcancer.2016.02.001. [Epub ahead of print] Review.

PMID:
26853158
2.

Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa.

Sumalatha M, Munikishore R, Rammohan A, Gunasekar D, Kumar KA, Reddy KK, Azad R, Reddanna P, Bodo B.

Nat Prod Commun. 2015 Oct;10(10):1703-4.

PMID:
26669106
3.

Phospholipase A2 Isoforms as Novel Targets for Prevention and Treatment of Inflammatory and Oncologic Diseases.

Yarla NS, Bishayee A, Vadlakonda L, Chintala R, Duddukuri GR, Reddanna P, Kaladhar DS.

Curr Drug Targets. 2015 Jul 27. [Epub ahead of print]

PMID:
26212262
4.

Structure Based Library Design (SBLD) for new 1,4-dihydropyrimidine scaffold as simultaneous COX-1/COX-2 and 5-LOX inhibitors.

Lokwani D, Azad R, Sarkate A, Reddanna P, Shinde D.

Bioorg Med Chem. 2015 Aug 1;23(15):4533-43. doi: 10.1016/j.bmc.2015.06.008. Epub 2015 Jun 11.

PMID:
26122769
6.

Exploration of binding site pattern in arachidonic acid metabolizing enzymes, Cyclooxygenases and Lipoxygenases.

Reddy KK, Vidya Rajan VK, Gupta A, Aparoy P, Reddanna P.

BMC Res Notes. 2015 Apr 16;8:152. doi: 10.1186/s13104-015-1101-4.

7.

Leukotriene signaling in the extinct human subspecies Homo denisovan and Homo neanderthalensis. Structural and functional comparison with Homo sapiens.

Adel S, Kakularam KR, Horn T, Reddanna P, Kuhn H, Heydeck D.

Arch Biochem Biophys. 2015 Jan 1;565:17-24. doi: 10.1016/j.abb.2014.10.012. Epub 2014 Nov 1.

PMID:
25447821
8.

15-LOX metabolites and angiogenesis: angiostatic effect of 15(S)-HPETE involves induction of apoptosis in adipose endothelial cells.

Soumya SJ, Binu S, Helen A, Reddanna P, Sudhakaran PR.

PeerJ. 2014 Oct 21;2:e635. doi: 10.7717/peerj.635. eCollection 2014.

9.

Draft Genome Sequence of the Field Isolate Brucella melitensis Strain Bm IND1 from India.

Rao SB, Gupta VK, Kumar M, Hegde NR, Splitter GA, Reddanna P, Radhakrishnan GK.

Genome Announc. 2014 May 29;2(3). pii: e00497-14. doi: 10.1128/genomeA.00497-14.

10.

The Pasteur's Dictum: Nitrogen Promotes Growth and Oxygen Reduces the Need for Sugar.

Vadlakonda L, Reddy VD, Pasupuleti M, Reddanna P.

Front Oncol. 2014 Mar 17;4:51. doi: 10.3389/fonc.2014.00051. eCollection 2014. Review. No abstract available.

11.

Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor.

Athira AP, Helen A, Saja K, Reddanna P, Sudhakaran PR.

Int J Vasc Med. 2013;2013:843897. doi: 10.1155/2013/843897. Epub 2013 Oct 31.

12.

Functional characterization of genetic enzyme variations in human lipoxygenases.

Horn T, Reddy Kakularam K, Anton M, Richter C, Reddanna P, Kuhn H.

Redox Biol. 2013 Nov 11;1:566-77. doi: 10.1016/j.redox.2013.11.001. eCollection 2013.

13.

15(S)-HETE-induced angiogenesis in adipose tissue is mediated through activation of PI3K/Akt/mTOR signaling pathway.

Soumya SJ, Binu S, Helen A, Reddanna P, Sudhakaran PR.

Biochem Cell Biol. 2013 Dec;91(6):498-505. doi: 10.1139/bcb-2013-0037. Epub 2013 Oct 17.

PMID:
24219292
14.

Molecular basis for the catalytic inactivity of a naturally occurring near-null variant of human ALOX15.

Horn T, Ivanov I, Di Venere A, Kakularam KR, Reddanna P, Conrad ML, Richter C, Scheerer P, Kuhn H.

Biochim Biophys Acta. 2013 Dec;1831(12):1702-13. doi: 10.1016/j.bbalip.2013.08.004. Epub 2013 Aug 16.

PMID:
23958500
15.

Free energy calculations to estimate ligand-binding affinities in structure-based drug design.

Reddy MR, Reddy CR, Rathore RS, Erion MD, Aparoy P, Reddy RN, Reddanna P.

Curr Pharm Des. 2014;20(20):3323-37. Review.

PMID:
23947646
16.

Did we get pasteur, warburg, and crabtree on a right note?

Vadlakonda L, Dash A, Pasupuleti M, Anil Kumar K, Reddanna P.

Front Oncol. 2013 Jul 15;3:186. doi: 10.3389/fonc.2013.00186. eCollection 2013. No abstract available.

17.

Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase.

Filosa R, Peduto A, Aparoy P, Schaible AM, Luderer S, Krauth V, Petronzi C, Massa A, de Rosa M, Reddanna P, Werz O.

Eur J Med Chem. 2013 Sep;67:269-79. doi: 10.1016/j.ejmech.2013.06.039. Epub 2013 Jun 27.

PMID:
23871907
18.

The Paradox of Akt-mTOR Interactions.

Vadlakonda L, Dash A, Pasupuleti M, Anil Kumar K, Reddanna P.

Front Oncol. 2013 Jun 20;3:165. doi: 10.3389/fonc.2013.00165. eCollection 2013.

19.

Advances in binding free energies calculations: QM/MM-based free energy perturbation method for drug design.

Rathore RS, Sumakanth M, Reddy MS, Reddanna P, Rao AA, Erion MD, Reddy MR.

Curr Pharm Des. 2013;19(26):4674-86. Review.

PMID:
23260025
20.

Conversion of pro-inflammatory murine Alox5 into an anti-inflammatory 15S-lipoxygenating enzyme by multiple mutations of sequence determinants.

Hofheinz K, Kakularam KR, Adel S, Anton M, Polymarasetty A, Reddanna P, Kuhn H, Horn T.

Arch Biochem Biophys. 2013 Feb 1;530(1):40-7. doi: 10.1016/j.abb.2012.11.015. Epub 2012 Dec 12.

PMID:
23246375
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