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Results: 1 to 20 of 307

1.

Tyr728 in the kinase domain of the murine kinase suppressor of RAS 1 regulates binding and activation of the mitogen-activated protein kinase kinase.

Sibilski C, Mueller T, Kollipara L, Zahedi RP, Rapp UR, Rudel T, Baljuls A.

J Biol Chem. 2013 Dec 6;288(49):35237-52. doi: 10.1074/jbc.M113.490235. Epub 2013 Oct 24.

PMID:
24158441
[PubMed - indexed for MEDLINE]
2.

Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum.

Pfeiffer V, Götz R, Xiang C, Camarero G, Braun A, Zhang Y, Blum R, Heinsen H, Nieswandt B, Rapp UR.

PLoS One. 2013;8(3):e58259. doi: 10.1371/journal.pone.0058259. Epub 2013 Mar 7.

PMID:
23505473
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

E-cadherin controls bronchiolar progenitor cells and onset of preneoplastic lesions in mice.

Ceteci F, Ceteci S, Zanucco E, Thakur C, Becker M, El-Nikhely N, Fink L, Seeger W, Savai R, Rapp UR.

Neoplasia. 2012 Dec;14(12):1164-77.

PMID:
23308049
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma.

Castro IC, Breiling A, Luetkenhaus K, Ceteci F, Hausmann S, Kress S, Lyko F, Rudel T, Rapp UR.

Mol Cancer Res. 2013 Feb;11(2):161-72. doi: 10.1158/1541-7786.MCR-12-0414-T. Epub 2012 Dec 13.

PMID:
23239811
[PubMed - indexed for MEDLINE]
Free Article
5.

MK3 controls Polycomb target gene expression via negative feedback on ERK.

Prickaerts P, Niessen HE, Mouchel-Vielh E, Dahlmans VE, van den Akker GG, Geijselaers C, Adriaens ME, Spaapen F, Takihara Y, Rapp UR, Peronnet F, Voncken JW.

Epigenetics Chromatin. 2012 Aug 7;5(1):12. doi: 10.1186/1756-8935-5-12.

PMID:
22870894
[PubMed]
Free PMC Article
6.

Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration.

Oberoi-Khanuja TK, Karreman C, Larisch S, Rapp UR, Rajalingam K.

J Biol Chem. 2012 Aug 17;287(34):28445-55. doi: 10.1074/jbc.M112.341297. Epub 2012 Jun 18.

PMID:
22711539
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF.

Baljuls A, Beck M, Oenel A, Robubi A, Kroschewski R, Hekman M, Rudel T, Rapp UR.

J Biol Chem. 2012 Jun 29;287(27):23128-40. doi: 10.1074/jbc.M112.343780. Epub 2012 May 17.

PMID:
22605333
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.

Oak PS, Kopp F, Thakur C, Ellwart JW, Rapp UR, Ullrich A, Wagner E, Knyazev P, Roidl A.

Int J Cancer. 2012 Dec 15;131(12):2808-19. doi: 10.1002/ijc.27595. Epub 2012 May 21.

PMID:
22511343
[PubMed - indexed for MEDLINE]
9.

Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice.

Zanucco E, Götz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR.

PLoS One. 2011;6(12):e29093. doi: 10.1371/journal.pone.0029093. Epub 2011 Dec 14.

PMID:
22194995
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Conditional expression of oncogenic C-RAF in mouse pulmonary epithelial cells reveals differential tumorigenesis and induction of autophagy leading to tumor regression.

Ceteci F, Xu J, Ceteci S, Zanucco E, Thakur C, Rapp UR.

Neoplasia. 2011 Nov;13(11):1005-18.

PMID:
22131876
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell lines.

Heisig M, Frentzen A, Bergmann B, Galmbacher K, Gentschev I, Hotz C, Schoen C, Stritzker J, Fensterle J, Rapp UR, Goebel W.

BMC Microbiol. 2011 Jul 11;11:163. doi: 10.1186/1471-2180-11-163.

PMID:
21745384
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Single substitution within the RKTR motif impairs kinase activity but promotes dimerization of RAF kinase.

Baljuls A, Mahr R, Schwarzenau I, Müller T, Polzien L, Hekman M, Rapp UR.

J Biol Chem. 2011 May 6;286(18):16491-503. doi: 10.1074/jbc.M110.194167. Epub 2011 Mar 18.

PMID:
21454547
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling.

Polzien L, Baljuls A, Albrecht M, Hekman M, Rapp UR.

J Biol Chem. 2011 May 20;286(20):17934-44. doi: 10.1074/jbc.M110.177345. Epub 2011 Feb 11.

PMID:
21317286
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Polycomb group protein Bmi1 negatively regulates IL-10 expression in activated macrophages.

Sienerth AR, Scheuermann C, Galmiche A, Rapp UR, Becker M.

Immunol Cell Biol. 2011 Oct;89(7):812-6. doi: 10.1038/icb.2010.160. Epub 2011 Jan 11.

PMID:
21221124
[PubMed - indexed for MEDLINE]
15.

RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development.

Magariños M, Aburto MR, Sánchez-Calderón H, Muñoz-Agudo C, Rapp UR, Varela-Nieto I.

PLoS One. 2010 Dec 28;5(12):e14435. doi: 10.1371/journal.pone.0014435.

PMID:
21203386
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Pore-forming activity of BAD is regulated by specific phosphorylation and structural transitions of the C-terminal part.

Polzien L, Baljuls A, Roth HM, Kuper J, Benz R, Schweimer K, Hekman M, Rapp UR.

Biochim Biophys Acta. 2011 Feb;1810(2):162-9. doi: 10.1016/j.bbagen.2010.11.002. Epub 2010 Nov 24.

PMID:
21081150
[PubMed - indexed for MEDLINE]
Free Article
17.

Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.

Molzan M, Schumacher B, Ottmann C, Baljuls A, Polzien L, Weyand M, Thiel P, Rose R, Rose M, Kuhenne P, Kaiser M, Rapp UR, Kuhlmann J, Ottmann C.

Mol Cell Biol. 2010 Oct;30(19):4698-711. doi: 10.1128/MCB.01636-09. Epub 2010 Aug 2.

PMID:
20679480
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regression.

Galmbacher K, Heisig M, Hotz C, Wischhusen J, Galmiche A, Bergmann B, Gentschev I, Goebel W, Rapp UR, Fensterle J.

PLoS One. 2010 Mar 8;5(3):e9572. doi: 10.1371/journal.pone.0009572.

PMID:
20221397
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Can BAD pores be good? New insights from examining BAD as a target of RAF kinases.

Polzien L, Benz R, Rapp UR.

Adv Enzyme Regul. 2010;50(1):147-59. doi: 10.1016/j.advenzreg.2009.10.025. Epub 2009 Nov 4. No abstract available.

PMID:
19895838
[PubMed - indexed for MEDLINE]
20.

Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation.

Polzien L, Baljuls A, Rennefahrt UE, Fischer A, Schmitz W, Zahedi RP, Sickmann A, Metz R, Albert S, Benz R, Hekman M, Rapp UR.

J Biol Chem. 2009 Oct 9;284(41):28004-20. doi: 10.1074/jbc.M109.010702. Epub 2009 Aug 10.

PMID:
19667065
[PubMed - indexed for MEDLINE]
Free PMC Article

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