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Results: 1 to 20 of 36

1.

Analysis of protein-RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry.

Sharma K, Hrle A, Kramer K, Sachsenberg T, Staals RH, Randau L, Marchfelder A, van der Oost J, Kohlbacher O, Conti E, Urlaub H.

Methods. 2015 Jun 10. pii: S1046-2023(15)00246-7. doi: 10.1016/j.ymeth.2015.06.005. [Epub ahead of print]

PMID:
26071038
2.

In Vitro Co-reconstitution of Cas Protein Complexes.

Plagens A, Randau L.

Methods Mol Biol. 2015;1311:23-33. doi: 10.1007/978-1-4939-2687-9_2.

PMID:
25981464
3.

DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes.

Plagens A, Richter H, Charpentier E, Randau L.

FEMS Microbiol Rev. 2015 May;39(3):442-63. doi: 10.1093/femsre/fuv019. Epub 2015 Apr 30. Review.

PMID:
25934119
4.

Evolution of small guide RNA genes in hyperthermophilic archaea.

Randau L.

Ann N Y Acad Sci. 2015 Apr;1341:188-93. doi: 10.1111/nyas.12643. Epub 2015 Jan 13.

PMID:
25585508
5.

DNA binding properties of the small cascade subunit Csa5.

Daume M, Plagens A, Randau L.

PLoS One. 2014 Aug 22;9(8):e105716. doi: 10.1371/journal.pone.0105716. eCollection 2014.

6.

Small regulatory RNAs in Archaea.

Babski J, Maier LK, Heyer R, Jaschinski K, Prasse D, Jäger D, Randau L, Schmitz RA, Marchfelder A, Soppa J.

RNA Biol. 2014;11(5):484-93. Epub 2014 Mar 31. Review.

7.

In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex.

Plagens A, Tripp V, Daume M, Sharma K, Klingl A, Hrle A, Conti E, Urlaub H, Randau L.

Nucleic Acids Res. 2014 Apr;42(8):5125-38. doi: 10.1093/nar/gku120. Epub 2014 Feb 5.

8.

A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii.

Brendel J, Stoll B, Lange SJ, Sharma K, Lenz C, Stachler AE, Maier LK, Richter H, Nickel L, Schmitz RA, Randau L, Allers T, Urlaub H, Backofen R, Marchfelder A.

J Biol Chem. 2014 Mar 7;289(10):7164-77. doi: 10.1074/jbc.M113.508184. Epub 2014 Jan 23.

9.

Small RNA-guided adaptive immunity: comment on "Diversity, evolution, and therapeutic applications of small RNAs in prokaryotic and eukaryotic immune systems" by Cooper and Overstreet.

Plagens A, Randau L.

Phys Life Rev. 2014 Mar;11(1):139-40; discussion 149-51. doi: 10.1016/j.plrev.2013.11.015. Epub 2013 Dec 2. No abstract available.

PMID:
24332806
10.

RNA-Seq analyses reveal CRISPR RNA processing and regulation patterns.

Zoephel J, Randau L.

Biochem Soc Trans. 2013 Dec;41(6):1459-63. doi: 10.1042/BST20130129. Review.

PMID:
24256237
11.

Structure and RNA-binding properties of the type III-A CRISPR-associated protein Csm3.

Hrle A, Su AA, Ebert J, Benda C, Randau L, Conti E.

RNA Biol. 2013 Nov;10(11):1670-8. doi: 10.4161/rna.26500. Epub 2013 Sep 30.

12.

Exploiting CRISPR/Cas: interference mechanisms and applications.

Richter H, Randau L, Plagens A.

Int J Mol Sci. 2013 Jul 12;14(7):14518-31. doi: 10.3390/ijms140714518. Review.

13.

RNA-Seq analyses reveal the order of tRNA processing events and the maturation of C/D box and CRISPR RNAs in the hyperthermophile Methanopyrus kandleri.

Su AA, Tripp V, Randau L.

Nucleic Acids Res. 2013 Jul;41(12):6250-8. doi: 10.1093/nar/gkt317. Epub 2013 Apr 25.

14.

Comparative analysis ofCas6b processing and CRISPR RNA stability.

Richter H, Lange SJ, Backofen R, Randau L.

RNA Biol. 2013 May;10(5):700-7.

15.

C/D box sRNA, CRISPR RNA and tRNA processing in an archaeon with a minimal fragmented genome.

Richter H, Mohr S, Randau L.

Biochem Soc Trans. 2013 Feb 1;41(1):411-5. doi: 10.1042/BST20120276. Review.

PMID:
23356320
16.

Substrate generation for endonucleases of CRISPR/cas systems.

Zoephel J, Dwarakanath S, Richter H, Plagens A, Randau L.

J Vis Exp. 2012 Sep 8;(67). pii: 4277. doi: 10.3791/4277.

17.

Characterization of CRISPR RNA processing in Clostridium thermocellum and Methanococcus maripaludis.

Richter H, Zoephel J, Schermuly J, Maticzka D, Backofen R, Randau L.

Nucleic Acids Res. 2012 Oct;40(19):9887-96. doi: 10.1093/nar/gks737. Epub 2012 Aug 8.

18.

RNA processing in the minimal organism Nanoarchaeum equitans.

Randau L.

Genome Biol. 2012 Jul 18;13(7):R63. doi: 10.1186/gb-2012-13-7-r63.

19.

Small RNAs for defence and regulation in archaea.

Marchfelder A, Fischer S, Brendel J, Stoll B, Maier LK, Jäger D, Prasse D, Plagens A, Schmitz RA, Randau L.

Extremophiles. 2012 Sep;16(5):685-96. doi: 10.1007/s00792-012-0469-5. Epub 2012 Jul 5. Review.

20.

Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax.

Plagens A, Tjaden B, Hagemann A, Randau L, Hensel R.

J Bacteriol. 2012 May;194(10):2491-500. doi: 10.1128/JB.00206-12. Epub 2012 Mar 9.

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