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Cell Signaling-Based Classifier Predicts Response to Induction Therapy in Elderly Patients with Acute Myeloid Leukemia.

Cesano A, Willman CL, Kopecky KJ, Gayko U, Putta S, Louie B, Westfall M, Purvis N, Spellmeyer DC, Marimpietri C, Cohen AC, Hackett J, Shi J, Walker MG, Sun Z, Paietta E, Tallman MS, Cripe LD, Atwater S, Appelbaum FR, Radich JP.

PLoS One. 2015 Apr 17;10(4):e0118485. doi: 10.1371/journal.pone.0118485. eCollection 2015.


Occipital seizures and subcortical T2 hypointensity in the setting of hyperglycemia.

Putta SL, Weisholtz D, Milligan TA.

Epilepsy Behav Case Rep. 2014 Apr 25;2:96-9. doi: 10.1016/j.ebcr.2014.01.001. eCollection 2014.


Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA.

Reddy MA, Chen Z, Park JT, Wang M, Lanting L, Zhang Q, Bhatt K, Leung A, Wu X, Putta S, Sætrom P, Devaraj S, Natarajan R.

Diabetes. 2014 Dec;63(12):4249-61. doi: 10.2337/db14-0298. Epub 2014 Jul 9.


High-dimensional analysis of the aging immune system: verification of age-associated differences in immune signaling responses in healthy donors.

Longo DM, Louie B, Ptacek J, Friedland G, Evensen E, Putta S, Atallah M, Spellmeyer D, Wang E, Pos Z, Marincola FM, Schaeffer A, Lukac S, Railkar R, Beals CR, Cesano A, Carayannopoulos LN, Hawtin RE.

J Transl Med. 2014 Jun 21;12:178. doi: 10.1186/1479-5876-12-178.


TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy.

Kato M, Dang V, Wang M, Park JT, Deshpande S, Kadam S, Mardiros A, Zhan Y, Oettgen P, Putta S, Yuan H, Lanting L, Natarajan R.

Sci Signal. 2013 Jun 4;6(278):ra43. doi: 10.1126/scisignal.2003389.


Development and validation of a single-cell network profiling assay-based classifier to predict response to induction therapy in paediatric patients with de novo acute myeloid leukaemia: a report from the Children's Oncology Group.

Lacayo NJ, Alonzo TA, Gayko U, Rosen DB, Westfall M, Purvis N, Putta S, Louie B, Hackett J, Cohen AC, Cesano A, Gerbing R, Ravindranath Y, Dahl GV, Gamis A, Meshinchi S.

Br J Haematol. 2013 Jul;162(2):250-62. doi: 10.1111/bjh.12370. Epub 2013 May 20.


Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy.

Deshpande SD, Putta S, Wang M, Lai JY, Bitzer M, Nelson RG, Lanting LL, Kato M, Natarajan R.

Diabetes. 2013 Sep;62(9):3151-62. doi: 10.2337/db13-0305. Epub 2013 May 6.


Salamander Hox clusters contain repetitive DNA and expanded non-coding regions: a typical Hox structure for non-mammalian tetrapod vertebrates?

Voss SR, Putta S, Walker JA, Smith JJ, Maki N, Tsonis PA.

Hum Genomics. 2013 Apr 5;7:9. doi: 10.1186/1479-7364-7-9.


Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational status.

Cesano A, Putta S, Rosen DB, Cohen AC, Gayko U, Mathi K, Woronicz J, Hawtin RE, Cripe L, Sun Z, Tallman MS, Paietta E.

PLoS One. 2013;8(2):e56714. doi: 10.1371/journal.pone.0056714. Epub 2013 Feb 19.


AKT signaling as a novel factor associated with in vitro resistance of human AML to gemtuzumab ozogamicin.

Rosen DB, Harrington KH, Cordeiro JA, Leung LY, Putta S, Lacayo N, Laszlo GS, Gudgeon CJ, Hogge DE, Hawtin RE, Cesano A, Walter RB.

PLoS One. 2013;8(1):e53518. doi: 10.1371/journal.pone.0053518. Epub 2013 Jan 8.


Gene expression patterns specific to the regenerating limb of the Mexican axolotl.

Monaghan JR, Athippozhy A, Seifert AW, Putta S, Stromberg AJ, Maden M, Gardiner DM, Voss SR.

Biol Open. 2012 Oct 15;1(10):937-48. doi: 10.1242/bio.20121594. Epub 2012 Jul 27.


MicroRNAs and diabetic complications.

Natarajan R, Putta S, Kato M.

J Cardiovasc Transl Res. 2012 Aug;5(4):413-22. doi: 10.1007/s12265-012-9368-5. Epub 2012 May 3. Review.


The case for brain death determination by CTA: where are the results?

Lamb T, Arumaithurai K, Shastri R, Putta S.

J Trauma Acute Care Surg. 2012 Apr;72(4):1123. doi: 10.1097/TA.0b013e318247885a. No abstract available.


Small RNA sequencing reveals microRNAs that modulate angiotensin II effects in vascular smooth muscle cells.

Jin W, Reddy MA, Chen Z, Putta S, Lanting L, Kato M, Park JT, Chandra M, Wang C, Tangirala RK, Natarajan R.

J Biol Chem. 2012 May 4;287(19):15672-83. doi: 10.1074/jbc.M111.322669. Epub 2012 Mar 19.


Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts.

Cesano A, Rosen DB, O'Meara P, Putta S, Gayko U, Spellmeyer DC, Cripe LD, Sun Z, Uno H, Litzow MR, Tallman MS, Paietta E.

Cytometry B Clin Cytom. 2012 May;82(3):158-72. doi: 10.1002/cyto.b.21007. Epub 2012 Feb 14.


Single-cell network profiling of peripheral blood mononuclear cells from healthy donors reveals age- and race-associated differences in immune signaling pathway activation.

Longo DM, Louie B, Putta S, Evensen E, Ptacek J, Cordeiro J, Wang E, Pos Z, Hawtin RE, Marincola FM, Cesano A.

J Immunol. 2012 Feb 15;188(4):1717-25. doi: 10.4049/jimmunol.1102514. Epub 2012 Jan 13.


Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy.

Putta S, Lanting L, Sun G, Lawson G, Kato M, Natarajan R.

J Am Soc Nephrol. 2012 Mar;23(3):458-69. doi: 10.1681/ASN.2011050485. Epub 2012 Jan 5.


Origin of amphibian and avian chromosomes by fission, fusion, and retention of ancestral chromosomes.

Voss SR, Kump DK, Putta S, Pauly N, Reynolds A, Henry RJ, Basa S, Walker JA, Smith JJ.

Genome Res. 2011 Aug;21(8):1306-12. doi: 10.1101/gr.116491.110. Epub 2011 Apr 11.


Identification of differentially expressed thyroid hormone responsive genes from the brain of the Mexican Axolotl (Ambystoma mexicanum).

Huggins P, Johnson CK, Schoergendorfer A, Putta S, Bathke AC, Stromberg AJ, Voss SR.

Comp Biochem Physiol C Toxicol Pharmacol. 2012 Jan;155(1):128-35. doi: 10.1016/j.cbpc.2011.03.006. Epub 2011 Mar 30.


A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells.

Kato M, Arce L, Wang M, Putta S, Lanting L, Natarajan R.

Kidney Int. 2011 Aug;80(4):358-68. doi: 10.1038/ki.2011.43. Epub 2011 Mar 9.

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