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Results: 1 to 20 of 124


Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.

Brisson BK, Mauldin EA, Lei W, Vogel LK, Power AM, Lo A, Dopkin D, Khanna C, Wells RG, Puré E, Volk SW.

Am J Pathol. 2015 May;185(5):1471-86. doi: 10.1016/j.ajpath.2015.01.029. Epub 2015 Mar 17.


A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.

Bae YH, Mui KL, Hsu BY, Liu SL, Cretu A, Razinia Z, Xu T, Puré E, Assoian RK.

Sci Signal. 2014 Jun 17;7(330):ra57. doi: 10.1126/scisignal.2004838.


Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.

Moon EK, Wang LC, Dolfi DV, Wilson CB, Ranganathan R, Sun J, Kapoor V, Scholler J, Puré E, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM.

Clin Cancer Res. 2014 Aug 15;20(16):4262-73. doi: 10.1158/1078-0432.CCR-13-2627. Epub 2014 Jun 11.


Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity.

Wang LC, Lo A, Scholler J, Sun J, Majumdar RS, Kapoor V, Antzis M, Cotner CE, Johnson LA, Durham AC, Solomides CC, June CH, Puré E, Albelda SM.

Cancer Immunol Res. 2014 Feb;2(2):154-66. doi: 10.1158/2326-6066.CIR-13-0027. Epub 2013 Nov 12.


Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice.

Chen L, Yang G, Monslow J, Todd L, Cormode DP, Tang J, Grant GR, DeLong JH, Tang SY, Lawson JA, Pure E, Fitzgerald GA.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6828-33. doi: 10.1073/pnas.1401797111. Epub 2014 Apr 21.


Cyclooxygenase-2 in endothelial and vascular smooth muscle cells restrains atherogenesis in hyperlipidemic mice.

Tang SY, Monslow J, Todd L, Lawson J, Puré E, FitzGerald GA.

Circulation. 2014 Apr 29;129(17):1761-9. doi: 10.1161/CIRCULATIONAHA.113.007913. Epub 2014 Feb 11.


Augmentation of integrin-mediated mechanotransduction by hyaluronic acid.

Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, Kresh JY, Janmey PA.

Biomaterials. 2014 Jan;35(1):71-82. doi: 10.1016/j.biomaterials.2013.09.066. Epub 2013 Oct 10.


Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.

Tchou J, Zhang PJ, Bi Y, Satija C, Marjumdar R, Stephen TL, Lo A, Chen H, Mies C, June CH, Conejo-Garcia J, Puré E.

Hum Pathol. 2013 Nov;44(11):2549-57. doi: 10.1016/j.humpath.2013.06.016. Epub 2013 Sep 26.


Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53.

Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL.

Cancer Res. 2013 Oct 1;73(19):5974-84. doi: 10.1158/0008-5472.CAN-13-1384. Epub 2013 Aug 13.


Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis.

Eisinger-Mathason TS, Zhang M, Qiu Q, Skuli N, Nakazawa MS, Karakasheva T, Mucaj V, Shay JE, Stangenberg L, Sadri N, Puré E, Yoon SS, Kirsch DG, Simon MC.

Cancer Discov. 2013 Oct;3(10):1190-205. doi: 10.1158/2159-8290.CD-13-0118. Epub 2013 Aug 1.


Development of drug loaded nanoparticles for tumor targeting. Part 1: Synthesis, characterization, and biological evaluation in 2D cell cultures.

El-Dakdouki MH, Puré E, Huang X.

Nanoscale. 2013 May 7;5(9):3895-903. doi: 10.1039/c3nr33777d. Epub 2013 Mar 26.


Pillars article: T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells. J. Exp. Med. 1982. 155: 734-748.

Isakson PC, Puré E, Vitetta ES, Krammer PH.

J Immunol. 2013 Feb 1;190(3):849-63. No abstract available.


Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening.

Kothapalli D, Liu SL, Bae YH, Monslow J, Xu T, Hawthorne EA, Byfield FJ, Castagnino P, Rao S, Rader DJ, Puré E, Phillips MC, Lund-Katz S, Janmey PA, Assoian RK.

Cell Rep. 2012 Nov 29;2(5):1259-71. doi: 10.1016/j.celrep.2012.09.018. Epub 2012 Oct 25.


Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.

Tchou J, Kossenkov AV, Chang L, Satija C, Herlyn M, Showe LC, Puré E.

BMC Med Genomics. 2012 Sep 6;5:39. doi: 10.1186/1755-8794-5-39.


Fibroblast activation protein in remodeling tissues.

Jacob M, Chang L, Puré E.

Curr Mol Med. 2012 Dec;12(10):1220-43. Review.


Vascular COX-2 modulates blood pressure and thrombosis in mice.

Yu Y, Ricciotti E, Scalia R, Tang SY, Grant G, Yu Z, Landesberg G, Crichton I, Wu W, Puré E, Funk CD, FitzGerald GA.

Sci Transl Med. 2012 May 2;4(132):132ra54. doi: 10.1126/scitranslmed.3003787.


Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice.

Yu Z, Crichton I, Tang SY, Hui Y, Ricciotti E, Levin MD, Lawson JA, Puré E, FitzGerald GA.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6727-32. doi: 10.1073/pnas.1115313109. Epub 2012 Apr 9.


Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.

Song WL, Stubbe J, Ricciotti E, Alamuddin N, Ibrahim S, Crichton I, Prempeh M, Lawson JA, Wilensky RL, Rasmussen LM, Puré E, FitzGerald GA.

J Clin Invest. 2012 Apr;122(4):1459-68. doi: 10.1172/JCI59262. Epub 2012 Mar 12.


Interferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.

Kinder M, Thompson JE, Wei C, Shelat SG, Blair IA, Carroll M, Puré E.

Exp Hematol. 2010 Nov;38(11):1036-1046.e1-4. doi: 10.1016/j.exphem.2010.07.004. Epub 2010 Jul 18.

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