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Items: 1 to 20 of 133

1.

Augmentation of CAR T-cell Trafficking and Antitumor Efficacy by Blocking Protein Kinase A Localization.

Newick K, O'Brien S, Sun J, Kapoor V, Maceyko S, Lo A, Puré E, Moon E, Albelda SM.

Cancer Immunol Res. 2016 Apr 4. [Epub ahead of print]

PMID:
27045023
2.

Can Targeting Stroma Pave the Way to Enhanced Antitumor Immunity and Immunotherapy of Solid Tumors?

Puré E, Lo A.

Cancer Immunol Res. 2016 Apr;4(4):269-78. doi: 10.1158/2326-6066.CIR-16-0011. Review.

PMID:
27036971
3.

Role for Hyaluronan Synthase 3 in the Response to Vascular Injury.

Puré E, Krolikoski M, Monslow J.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):224-5. doi: 10.1161/ATVBAHA.115.306869. No abstract available.

PMID:
26819465
4.

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice.

Fan MH, Zhu Q, Li HH, Ra HJ, Majumdar S, Gulick DL, Jerome JA, Madsen DH, Christofidou-Solomidou M, Speicher DW, Bachovchin WW, Feghali-Bostwick C, Puré E.

J Biol Chem. 2016 Apr 8;291(15):8070-89. doi: 10.1074/jbc.M115.701433. Epub 2015 Dec 9.

PMID:
26663085
5.

Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening.

Liu SL, Bae YH, Yu C, Monslow J, Hawthorne EA, Castagnino P, Branchetti E, Ferrari G, Damrauer SM, Puré E, Assoian RK.

Sci Rep. 2015 Nov 26;5:17189. doi: 10.1038/srep17189.

6.

Nanoparticles functionalized with collagenase exhibit improved tumor accumulation in a murine xenograft model.

Murty S, Gilliland T, Qiao P, Tabtieng T, Higbee E, Al Zaki A, Puré E, Tsourkas A.

Part Part Syst Charact. 2014 Dec;31(12):1307-1312.

7.

Hyaluronan - a functional and structural sweet spot in the tissue microenvironment.

Monslow J, Govindaraju P, Puré E.

Front Immunol. 2015 May 15;6:231. doi: 10.3389/fimmu.2015.00231. eCollection 2015. Review.

8.

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.

Lo A, Wang LC, Scholler J, Monslow J, Avery D, Newick K, O'Brien S, Evans RA, Bajor DJ, Clendenin C, Durham AC, Buza EL, Vonderheide RH, June CH, Albelda SM, Puré E.

Cancer Res. 2015 Jul 15;75(14):2800-10. doi: 10.1158/0008-5472.CAN-14-3041. Epub 2015 May 15.

PMID:
25979873
9.

Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors.

Wang E, Wang LC, Tsai CY, Bhoj V, Gershenson Z, Moon E, Newick K, Sun J, Lo A, Baradet T, Feldman MD, Barrett D, Puré E, Albelda S, Milone MC.

Cancer Immunol Res. 2015 Jul;3(7):815-26. doi: 10.1158/2326-6066.CIR-15-0054. Epub 2015 May 4.

PMID:
25941351
10.

Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.

Brisson BK, Mauldin EA, Lei W, Vogel LK, Power AM, Lo A, Dopkin D, Khanna C, Wells RG, Puré E, Volk SW.

Am J Pathol. 2015 May;185(5):1471-86. doi: 10.1016/j.ajpath.2015.01.029. Epub 2015 Mar 17.

11.

A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.

Bae YH, Mui KL, Hsu BY, Liu SL, Cretu A, Razinia Z, Xu T, Puré E, Assoian RK.

Sci Signal. 2014 Jun 17;7(330):ra57. doi: 10.1126/scisignal.2004838.

12.

Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.

Moon EK, Wang LC, Dolfi DV, Wilson CB, Ranganathan R, Sun J, Kapoor V, Scholler J, Puré E, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM.

Clin Cancer Res. 2014 Aug 15;20(16):4262-73. doi: 10.1158/1078-0432.CCR-13-2627. Epub 2014 Jun 11.

13.

Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity.

Wang LC, Lo A, Scholler J, Sun J, Majumdar RS, Kapoor V, Antzis M, Cotner CE, Johnson LA, Durham AC, Solomides CC, June CH, Puré E, Albelda SM.

Cancer Immunol Res. 2014 Feb;2(2):154-66. doi: 10.1158/2326-6066.CIR-13-0027. Epub 2013 Nov 12.

14.

Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice.

Chen L, Yang G, Monslow J, Todd L, Cormode DP, Tang J, Grant GR, DeLong JH, Tang SY, Lawson JA, Pure E, Fitzgerald GA.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6828-33. doi: 10.1073/pnas.1401797111. Epub 2014 Apr 21.

15.

Cyclooxygenase-2 in endothelial and vascular smooth muscle cells restrains atherogenesis in hyperlipidemic mice.

Tang SY, Monslow J, Todd L, Lawson J, Puré E, FitzGerald GA.

Circulation. 2014 Apr 29;129(17):1761-9. doi: 10.1161/CIRCULATIONAHA.113.007913. Epub 2014 Feb 11.

16.

Augmentation of integrin-mediated mechanotransduction by hyaluronic acid.

Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, Kresh JY, Janmey PA.

Biomaterials. 2014 Jan;35(1):71-82. doi: 10.1016/j.biomaterials.2013.09.066. Epub 2013 Oct 10.

17.

Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.

Tchou J, Zhang PJ, Bi Y, Satija C, Marjumdar R, Stephen TL, Lo A, Chen H, Mies C, June CH, Conejo-Garcia J, Puré E.

Hum Pathol. 2013 Nov;44(11):2549-57. doi: 10.1016/j.humpath.2013.06.016. Epub 2013 Sep 26.

18.

Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53.

Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL.

Cancer Res. 2013 Oct 1;73(19):5974-84. doi: 10.1158/0008-5472.CAN-13-1384. Epub 2013 Aug 13.

19.

Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis.

Eisinger-Mathason TS, Zhang M, Qiu Q, Skuli N, Nakazawa MS, Karakasheva T, Mucaj V, Shay JE, Stangenberg L, Sadri N, Puré E, Yoon SS, Kirsch DG, Simon MC.

Cancer Discov. 2013 Oct;3(10):1190-205. doi: 10.1158/2159-8290.CD-13-0118. Epub 2013 Aug 1.

20.
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