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Results: 19

1.

Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.

Zheng CL, Wang NJ, Chung J, Moslehi H, Sanborn JZ, Hur JS, Collisson EA, Vemula SS, Naujokas A, Chiotti KE, Cheng JB, Fassihi H, Blumberg AJ, Bailey CV, Fudem GM, Mihm FG, Cunningham BB, Neuhaus IM, Liao W, Oh DH, Cleaver JE, LeBoit PE, Costello JF, Lehmann AR, Gray JW, Spellman PT, Arron ST, Huh N, Purdom E, Cho RJ.

Cell Rep. 2014 Nov 20;9(4):1228-34. doi: 10.1016/j.celrep.2014.10.031. Epub 2014 Nov 20.

PMID:
25456125
[PubMed - in process]
Free PMC Article
2.

Methods and challenges in timing chromosomal abnormalities within cancer samples.

Purdom E, Ho C, Grasso CS, Quist MJ, Cho RJ, Spellman P.

Bioinformatics. 2013 Dec 15;29(24):3113-20. doi: 10.1093/bioinformatics/btt546. Epub 2013 Sep 23.

PMID:
24064421
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Determining epithelial contribution to in vivo mesenchymal tumour expression signature using species-specific microarray profiling analysis of xenografts.

Purdom E, Restall C, Busuttil RA, Schluter H, Boussioutas A, Thompson EW, Anderson RL, Speed TP, Haviv I.

Genet Res (Camb). 2013 Feb;95(1):14-29. doi: 10.1017/S0016672313000013. Epub 2013 Mar 18.

PMID:
23497823
[PubMed - indexed for MEDLINE]
4.

A Tetrahymena Piwi bound to mature tRNA 3' fragments activates the exonuclease Xrn2 for RNA processing in the nucleus.

Couvillion MT, Bounova G, Purdom E, Speed TP, Collins K.

Mol Cell. 2012 Nov 30;48(4):509-20. doi: 10.1016/j.molcel.2012.09.010. Epub 2012 Oct 18.

PMID:
23084833
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Subtype and pathway specific responses to anticancer compounds in breast cancer.

Heiser LM, Sadanandam A, Kuo WL, Benz SC, Goldstein TC, Ng S, Gibb WJ, Wang NJ, Ziyad S, Tong F, Bayani N, Hu Z, Billig JI, Dueregger A, Lewis S, Jakkula L, Korkola JE, Durinck S, Pepin F, Guan Y, Purdom E, Neuvial P, Bengtsson H, Wood KW, Smith PG, Vassilev LT, Hennessy BT, Greshock J, Bachman KE, Hardwicke MA, Park JW, Marton LJ, Wolf DM, Collisson EA, Neve RM, Mills GB, Speed TP, Feiler HS, Wooster RF, Haussler D, Stuart JM, Gray JW, Spellman PT.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2724-9. doi: 10.1073/pnas.1018854108. Epub 2011 Oct 14.

PMID:
22003129
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Temporal dissection of tumorigenesis in primary cancers.

Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW, Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz G, Cibulskis K, Aster JC, Huang H, Purdom E, Li J, Bolund L, Arron ST, Gray JW, Spellman PT, Cho RJ.

Cancer Discov. 2011 Jul;1(2):137-43. doi: 10.1158/2159-8290.CD-11-0028. Epub 2011 Jun 29.

PMID:
21984974
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Unifying gene expression measures from multiple platforms using factor analysis.

Wang XV, Verhaak RG, Purdom E, Spellman PT, Speed TP.

PLoS One. 2011 Mar 11;6(3):e17691. doi: 10.1371/journal.pone.0017691.

PMID:
21436879
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Exon-level microarray analyses identify alternative splicing programs in breast cancer.

Lapuk A, Marr H, Jakkula L, Pedro H, Bhattacharya S, Purdom E, Hu Z, Simpson K, Pachter L, Durinck S, Wang N, Parvin B, Fontenay G, Speed T, Garbe J, Stampfer M, Bayandorian H, Dorton S, Clark TA, Schweitzer A, Wyrobek A, Feiler H, Spellman P, Conboy J, Gray JW.

Mol Cancer Res. 2010 Jul;8(7):961-74. doi: 10.1158/1541-7786.MCR-09-0528. Epub 2010 Jul 6.

PMID:
20605923
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments.

Bullard JH, Purdom E, Hansen KD, Dudoit S.

BMC Bioinformatics. 2010 Feb 18;11:94. doi: 10.1186/1471-2105-11-94.

PMID:
20167110
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.

Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN; Cancer Genome Atlas Research Network.

Cancer Cell. 2010 Jan 19;17(1):98-110. doi: 10.1016/j.ccr.2009.12.020.

PMID:
20129251
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

FIRMA: a method for detection of alternative splicing from exon array data.

Purdom E, Simpson KM, Robinson MD, Conboy JG, Lapuk AV, Speed TP.

Bioinformatics. 2008 Aug 1;24(15):1707-14. doi: 10.1093/bioinformatics/btn284. Epub 2008 Jun 23.

PMID:
18573797
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pneumosinus dilatans.

Nowlin TP 4th, Hall DJ, Purdom EB, Holtel MR.

Ear Nose Throat J. 2007 May;86(5):290-1.

PMID:
17580810
[PubMed - indexed for MEDLINE]
13.

Acute airway obstruction from a thyroglossal duct cyst.

Purdom E, Robitschek J, Littlefield PD, Cable B.

Otolaryngol Head Neck Surg. 2007 Feb;136(2):317-8. No abstract available.

PMID:
17275565
[PubMed - indexed for MEDLINE]
14.

Error distribution for gene expression data.

Purdom E, Holmes SP.

Stat Appl Genet Mol Biol. 2005;4:Article16. Epub 2005 Jul 12.

PMID:
16646833
[PubMed]
15.

Molecular analysis of the bacterial microbiota in the human stomach.

Bik EM, Eckburg PB, Gill SR, Nelson KE, Purdom EA, Francois F, Perez-Perez G, Blaser MJ, Relman DA.

Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):732-7. Epub 2006 Jan 4.

PMID:
16407106
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Osteoradionecrosis of the cervical spine resulting from radiotherapy for primary head and neck malignancies: operative and nonoperative management. Case report.

Donovan DJ, Huynh TV, Purdom EB, Johnson RE, Sniezek JC.

J Neurosurg Spine. 2005 Aug;3(2):159-64.

PMID:
16370306
[PubMed - indexed for MEDLINE]
17.

Diversity of the human intestinal microbial flora.

Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA.

Science. 2005 Jun 10;308(5728):1635-8. Epub 2005 Apr 14.

PMID:
15831718
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Microarray analysis reveals differences in gene expression of circulating CD8(+) T cells in melanoma patients and healthy donors.

Xu T, Shu CT, Purdom E, Dang D, Ilsley D, Guo Y, Weber J, Holmes SP, Lee PP.

Cancer Res. 2004 May 15;64(10):3661-7.

PMID:
15150126
[PubMed - indexed for MEDLINE]
Free Article
19.

The use of radioisotopes as tracers in cigarette smoke.

WOLFF WA, PURDOM EG, ISENHOWER JA.

N C Med J. 1954 Apr;15(4):159-63. No abstract available.

PMID:
13154697
[PubMed - indexed for MEDLINE]
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