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Items: 1 to 20 of 105


msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.

Raj A, Shim H, Gilad Y, Pritchard JK, Stephens M.

PLoS One. 2015 Sep 25;10(9):e0138030. doi: 10.1371/journal.pone.0138030. eCollection 2015.


WASP: allele-specific software for robust molecular quantitative trait locus discovery.

van de Geijn B, McVicker G, Gilad Y, Pritchard JK.

Nat Methods. 2015 Nov;12(11):1061-3. doi: 10.1038/nmeth.3582. Epub 2015 Sep 14.


Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions.

Grubert F, Zaugg JB, Kasowski M, Ursu O, Spacek DV, Martin AR, Greenside P, Srivas R, Phanstiel DH, Pekowska A, Heidari N, Euskirchen G, Huber W, Pritchard JK, Bustamante CD, Steinmetz LM, Kundaje A, Snyder M.

Cell. 2015 Aug 27;162(5):1051-65. doi: 10.1016/j.cell.2015.07.048. Epub 2015 Aug 20.


Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature.

Thomas SM, Kagan C, Pavlovic BJ, Burnett J, Patterson K, Pritchard JK, Gilad Y.

PLoS Genet. 2015 May 7;11(5):e1005216. doi: 10.1371/journal.pgen.1005216. eCollection 2015 May.


Genomic variation. Impact of regulatory variation from RNA to protein.

Battle A, Khan Z, Wang SH, Mitrano A, Ford MJ, Pritchard JK, Gilad Y.

Science. 2015 Feb 6;347(6222):664-7. doi: 10.1126/science.1260793. Epub 2014 Dec 18.


The genetic and mechanistic basis for variation in gene regulation.

Pai AA, Pritchard JK, Gilad Y.

PLoS Genet. 2015 Jan 8;11(1):e1004857. doi: 10.1371/journal.pgen.1004857. eCollection 2015 Jan.


Epigenetic modifications are associated with inter-species gene expression variation in primates.

Zhou X, Cain CE, Myrthil M, Lewellen N, Michelini K, Davenport ER, Stephens M, Pritchard JK, Gilad Y.

Genome Biol. 2014;15(12):547.


Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.

Banovich NE, Lan X, McVicker G, van de Geijn B, Degner JF, Blischak JD, Roux J, Pritchard JK, Gilad Y.

PLoS Genet. 2014 Sep 18;10(9):e1004663. doi: 10.1371/journal.pgen.1004663. eCollection 2014 Sep.


The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines.

Çalışkan M, Pritchard JK, Ober C, Gilad Y.

PLoS One. 2014 Sep 5;9(9):e107166. doi: 10.1371/journal.pone.0107166. eCollection 2014.


fastSTRUCTURE: variational inference of population structure in large SNP data sets.

Raj A, Stephens M, Pritchard JK.

Genetics. 2014 Jun;197(2):573-89. doi: 10.1534/genetics.114.164350. Epub 2014 Apr 2.


The functional consequences of variation in transcription factor binding.

Cusanovich DA, Pavlovic B, Pritchard JK, Gilad Y.

PLoS Genet. 2014 Mar 6;10(3):e1004226. doi: 10.1371/journal.pgen.1004226. eCollection 2014 Mar.


Admixture facilitates genetic adaptations to high altitude in Tibet.

Jeong C, Alkorta-Aranburu G, Basnyat B, Neupane M, Witonsky DB, Pritchard JK, Beall CM, Di Rienzo A.

Nat Commun. 2014;5:3281. doi: 10.1038/ncomms4281.


The deleterious mutation load is insensitive to recent population history.

Simons YB, Turchin MC, Pritchard JK, Sella G.

Nat Genet. 2014 Mar;46(3):220-4. doi: 10.1038/ng.2896. Epub 2014 Feb 9.


The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation.

Nalabothula N, McVicker G, Maiorano J, Martin R, Pritchard JK, Fondufe-Mittendorf YN.

BMC Genomics. 2014 Feb 1;15:92. doi: 10.1186/1471-2164-15-92.


Archaic humans: Four makes a party.

Birney E, Pritchard JK.

Nature. 2014 Jan 2;505(7481):32-4. doi: 10.1038/nature12847. Epub 2013 Dec 18. No abstract available.


Identification of genetic variants that affect histone modifications in human cells.

McVicker G, van de Geijn B, Degner JF, Cain CE, Banovich NE, Raj A, Lewellen N, Myrthil M, Gilad Y, Pritchard JK.

Science. 2013 Nov 8;342(6159):747-9. doi: 10.1126/science.1242429. Epub 2013 Oct 17.


Primate transcript and protein expression levels evolve under compensatory selection pressures.

Khan Z, Ford MJ, Cusanovich DA, Mitrano A, Pritchard JK, Gilad Y.

Science. 2013 Nov 29;342(6162):1100-4. doi: 10.1126/science.1242379. Epub 2013 Oct 17.



Pritchard JK.

Behav Anal Pract. 2013 Spring;6(1):96-100.


The genetic architecture of adaptations to high altitude in Ethiopia.

Alkorta-Aranburu G, Beall CM, Witonsky DB, Gebremedhin A, Pritchard JK, Di Rienzo A.

PLoS Genet. 2012;8(12):e1003110. doi: 10.1371/journal.pgen.1003110. Epub 2012 Dec 6.


Controls of nucleosome positioning in the human genome.

Gaffney DJ, McVicker G, Pai AA, Fondufe-Mittendorf YN, Lewellen N, Michelini K, Widom J, Gilad Y, Pritchard JK.

PLoS Genet. 2012;8(11):e1003036. doi: 10.1371/journal.pgen.1003036. Epub 2012 Nov 15.

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