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Items: 1 to 20 of 193

1.

Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue in spontaneously hypertensive rat.

Pravenec M, Mlejnek P, Zidek V, Landa V, Simakova M, Silhavy J, Strnad H, Eigner S, Eigner-Henke K, Skop V, Malinska H, Trnovska J, Kazdova L, Drahota Z, Mracek T, Houstek J.

Physiol Genomics. 2016 Apr 25:physiolgenomics.00122.2015. doi: 10.1152/physiolgenomics.00122.2015. [Epub ahead of print]

PMID:
27113533
2.

Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model.

Šedová L, Pravenec M, Křenová D, Kazdová L, Zídek V, Krupková M, Liška F, Křen V, Šeda O.

PLoS One. 2016 Mar 31;11(3):e0152708. doi: 10.1371/journal.pone.0152708. eCollection 2016.

3.

Effects of Metformin on Tissue Oxidative and Dicarbonyl Stress in Transgenic Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein.

Malínská H, Oliyarnyk O, Škop V, Šilhavý J, Landa V, Zídek V, Mlejnek P, Šimáková M, Strnad H, Kazdová L, Pravenec M.

PLoS One. 2016 Mar 10;11(3):e0150924. doi: 10.1371/journal.pone.0150924. eCollection 2016.

4.

Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to Metabolic Syndrome.

Pravenec M, Kožich V, Krijt J, Sokolová J, Zídek V, Landa V, Mlejnek P, Šilhavý J, Šimáková M, Škop V, Trnovská J, Kazdová L, Kajiya T, Wang J, Kurtz TW.

Hypertension. 2016 Feb;67(2):335-41. doi: 10.1161/HYPERTENSIONAHA.115.06158. Epub 2015 Dec 14.

PMID:
26667416
5.

Translational regulation shapes the molecular landscape of complex disease phenotypes.

Schafer S, Adami E, Heinig M, Rodrigues KE, Kreuchwig F, Silhavy J, van Heesch S, Simaite D, Rajewsky N, Cuppen E, Pravenec M, Vingron M, Cook SA, Hubner N.

Nat Commun. 2015 May 26;6:7200. doi: 10.1038/ncomms8200.

6.

histoneHMM: Differential analysis of histone modifications with broad genomic footprints.

Heinig M, Colomé-Tatché M, Taudt A, Rintisch C, Schafer S, Pravenec M, Hubner N, Vingron M, Johannes F.

BMC Bioinformatics. 2015 Feb 22;16:60. doi: 10.1186/s12859-015-0491-6.

7.

Molecular-based mechanisms of Mendelian forms of salt-dependent hypertension: questioning the prevailing theory.

Kurtz TW, Dominiczak AF, DiCarlo SE, Pravenec M, Morris RC Jr.

Hypertension. 2015 May;65(5):932-41. doi: 10.1161/HYPERTENSIONAHA.114.05092. Epub 2015 Mar 9. Review.

PMID:
25753977
8.

Rosuvastatin ameliorates inflammation, renal fat accumulation, and kidney injury in transgenic spontaneously hypertensive rats expressing human C-reactive protein.

Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Oliyarnyk O, Malínská H, Kazdová L, Mancini M, Pravenec M.

Physiol Res. 2015;64(3):295-301. Epub 2014 Dec 22.

9.

Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease.

Johnson MD, Mueller M, Adamowicz-Brice M, Collins MJ, Gellert P, Maratou K, Srivastava PK, Rotival M, Butt S, Game L, Atanur SS, Silver N, Norsworthy PJ, Langley SR, Petretto E, Pravenec M, Aitman TJ.

PLoS Genet. 2014 Dec 4;10(12):e1004813. doi: 10.1371/journal.pgen.1004813. eCollection 2014 Dec.

10.

Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat.

Trnovská J, Šilhavý J, Zídek V, Šimáková M, Mlejnek P, Landa V, Eigner S, Eigner Henke K, Škop V, Oliyarnyk O, Kazdová L, Mráček T, Houštěk J, Pravenec M.

Physiol Res. 2015;64(1):51-60. Epub 2014 Sep 5.

11.

Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction.

Houštěk J, Vrbacký M, Hejzlarová K, Zídek V, Landa V, Šilhavý J, Šimáková M, Mlejnek P, Kazdová L, Mikšík I, Neckář J, Papoušek F, Kolář F, Kurtz TW, Pravenec M.

Physiol Genomics. 2014 Sep 15;46(18):671-8. doi: 10.1152/physiolgenomics.00069.2014. Epub 2014 Jul 29.

12.

Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats.

Šilhavý J, Zídek V, Mlejnek P, Landa V, Šimáková M, Strnad H, Oliyarnyk O, Škop V, Kazdová L, Kurtz T, Pravenec M.

PLoS One. 2014 Jul 10;9(7):e101906. doi: 10.1371/journal.pone.0101906. eCollection 2014.

13.

Sterol regulatory element binding protein 2 overexpression is associated with reduced adipogenesis and ectopic fat accumulation in transgenic spontaneously hypertensive rats.

Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavý J, Trnovská J, Kazdová L, Pravenec M.

Physiol Res. 2014;63(5):587-90. Epub 2014 Jun 5.

14.

Natural variation of histone modification and its impact on gene expression in the rat genome.

Rintisch C, Heinig M, Bauerfeind A, Schafer S, Mieth C, Patone G, Hummel O, Chen W, Cook S, Cuppen E, Colomé-Tatché M, Johannes F, Jansen RC, Neil H, Werner M, Pravenec M, Vingron M, Hubner N.

Genome Res. 2014 Jun;24(6):942-53. doi: 10.1101/gr.169029.113. Epub 2014 May 2.

15.

Pharmacogenetic analysis of captopril effects on blood pressure: possible role of the Ednrb (endothelin receptor type B) candidate gene.

Zicha J, Dobešová Z, Zídek V, Silhavý J, Simáková M, Mlejnek P, Vaněčková I, Kuneš J, Pravenec M.

Physiol Res. 2014;63(2):263-5.

16.

Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons.

Ivics Z, Garrels W, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Kues WA, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):810-27. doi: 10.1038/nprot.2014.010. Epub 2014 Mar 13.

PMID:
24625780
17.

Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons.

Ivics Z, Hiripi L, Hoffmann OI, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Bösze Z, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):794-809. doi: 10.1038/nprot.2014.009. Epub 2014 Mar 13.

PMID:
24625779
18.

Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons.

Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):773-93. doi: 10.1038/nprot.2014.008. Epub 2014 Mar 13.

PMID:
24625778
19.

Recent progress in the genetics of spontaneously hypertensive rats.

Pravenec M, Křen V, Landa V, Mlejnek P, Musilová A, Šilhavý J, Šimáková M, Zídek V.

Physiol Res. 2014;63 Suppl 1:S1-8. Review.

20.

Rosuvastatin can block pro-inflammatory actions of transgenic human C-reactive protein without reducing its circulating levels.

Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Škop V, Oliyarnyk O, Kazdová L, Mancini M, Saar K, Schulz H, Hübner N, Kurtz TW, Pravenec M.

Cardiovasc Ther. 2014 Apr;32(2):59-65. doi: 10.1111/1755-5922.12061.

PMID:
24410968
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