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Results: 1 to 20 of 186

1.

Rosuvastatin ameliorates inflammation, renal fat accumulation, and kidney injury in transgenic spontaneously hypertensive rats expressing human C-reactive protein.

Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Oliyarnyk O, Malínská H, Kazdová L, Mancini M, Pravenec M.

Physiol Res. 2014 Dec 22. [Epub ahead of print]

PMID:
25536316
[PubMed - as supplied by publisher]
Free Article
2.

Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease.

Johnson MD, Mueller M, Adamowicz-Brice M, Collins MJ, Gellert P, Maratou K, Srivastava PK, Rotival M, Butt S, Game L, Atanur SS, Silver N, Norsworthy PJ, Langley SR, Petretto E, Pravenec M, Aitman TJ.

PLoS Genet. 2014 Dec 4;10(12):e1004813. doi: 10.1371/journal.pgen.1004813. eCollection 2014 Dec.

PMID:
25474312
[PubMed - in process]
Free PMC Article
3.

Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat.

Trnovská J, Silhavý J, Zídek V, Simáková M, Mlejnek P, Landa V, Eigner S, Eigner Henke K, Skop V, Oliyarnyk O, Kazdová L, Mráček T, Houštěk J, Pravenec M.

Physiol Res. 2014 Sep 5. [Epub ahead of print]

PMID:
25194136
[PubMed - as supplied by publisher]
Free Article
4.

Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction.

Houštěk J, Vrbacký M, Hejzlarová K, Zídek V, Landa V, Šilhavý J, Šimáková M, Mlejnek P, Kazdová L, Mikšík I, Neckář J, Papoušek F, Kolář F, Kurtz TW, Pravenec M.

Physiol Genomics. 2014 Sep 15;46(18):671-8. doi: 10.1152/physiolgenomics.00069.2014. Epub 2014 Jul 29.

PMID:
25073601
[PubMed - in process]
5.

Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats.

Šilhavý J, Zídek V, Mlejnek P, Landa V, Šimáková M, Strnad H, Oliyarnyk O, Škop V, Kazdová L, Kurtz T, Pravenec M.

PLoS One. 2014 Jul 10;9(7):e101906. doi: 10.1371/journal.pone.0101906. eCollection 2014.

PMID:
25010431
[PubMed - in process]
Free PMC Article
6.

Sterol regulatory element binding protein 2 overexpression is associated with reduced adipogenesis and ectopic fat accumulation in transgenic spontaneously hypertensive rats.

Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavý J, Trnovská J, Kazdová L, Pravenec M.

Physiol Res. 2014;63(5):587-90. Epub 2014 Jun 5.

PMID:
24908080
[PubMed - in process]
Free Article
7.

Natural variation of histone modification and its impact on gene expression in the rat genome.

Rintisch C, Heinig M, Bauerfeind A, Schafer S, Mieth C, Patone G, Hummel O, Chen W, Cook S, Cuppen E, Colomé-Tatché M, Johannes F, Jansen RC, Neil H, Werner M, Pravenec M, Vingron M, Hubner N.

Genome Res. 2014 Jun;24(6):942-53. doi: 10.1101/gr.169029.113. Epub 2014 May 2.

PMID:
24793478
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Pharmacogenetic analysis of captopril effects on blood pressure: possible role of the Ednrb (endothelin receptor type B) candidate gene.

Zicha J, Dobešová Z, Zídek V, Silhavý J, Simáková M, Mlejnek P, Vaněčková I, Kuneš J, Pravenec M.

Physiol Res. 2014;63(2):263-5.

PMID:
24779608
[PubMed - indexed for MEDLINE]
Free Article
9.

Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons.

Ivics Z, Garrels W, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Kues WA, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):810-27. doi: 10.1038/nprot.2014.010. Epub 2014 Mar 13.

PMID:
24625780
[PubMed - in process]
10.

Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons.

Ivics Z, Hiripi L, Hoffmann OI, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Bösze Z, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):794-809. doi: 10.1038/nprot.2014.009. Epub 2014 Mar 13.

PMID:
24625779
[PubMed - in process]
11.

Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons.

Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):773-93. doi: 10.1038/nprot.2014.008. Epub 2014 Mar 13.

PMID:
24625778
[PubMed - in process]
12.

Recent progress in the genetics of spontaneously hypertensive rats.

Pravenec M, Křen V, Landa V, Mlejnek P, Musilová A, Šilhavý J, Šimáková M, Zídek V.

Physiol Res. 2014;63 Suppl 1:S1-8. Review.

PMID:
24564651
[PubMed - indexed for MEDLINE]
Free Article
13.

Rosuvastatin can block pro-inflammatory actions of transgenic human C-reactive protein without reducing its circulating levels.

Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Škop V, Oliyarnyk O, Kazdová L, Mancini M, Saar K, Schulz H, Hübner N, Kurtz TW, Pravenec M.

Cardiovasc Ther. 2014 Apr;32(2):59-65. doi: 10.1111/1755-5922.12061.

PMID:
24410968
[PubMed - indexed for MEDLINE]
14.

Plzf as a candidate gene predisposing the spontaneously hypertensive rat to hypertension, left ventricular hypertrophy, and interstitial fibrosis.

Liška F, Mancini M, Krupková M, Chylíková B, Křenová D, Šeda O, Šilhavý J, Mlejnek P, Landa V, Zídek V, d' Amati G, Pravenec M, Křen V.

Am J Hypertens. 2014 Jan;27(1):99-106. doi: 10.1093/ajh/hpt156. Epub 2013 Aug 23.

PMID:
23975223
[PubMed - indexed for MEDLINE]
15.

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension.

Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, Ziegler MG, Schork NJ, Pravenec M, Mahata SK, Schmid-Schönbein GW, O'Connor DT.

Hum Mol Genet. 2013 Sep 15;22(18):3624-40. doi: 10.1093/hmg/ddt213. Epub 2013 May 13.

PMID:
23674521
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transgenic rescue of defective Cd36 enhances myocardial adenylyl cyclase signaling in spontaneously hypertensive rats.

Klevstig M, Manakov D, Kasparova D, Brabcova I, Papousek F, Zurmanova J, Zidek V, Silhavy J, Neckar J, Pravenec M, Kolar F, Novakova O, Novotny J.

Pflugers Arch. 2013 Oct;465(10):1477-86. doi: 10.1007/s00424-013-1281-5. Epub 2013 May 1.

PMID:
23636771
[PubMed - indexed for MEDLINE]
17.

Tissue-specific peroxisome proliferator activated receptor gamma expression and metabolic effects of telmisartan.

Zídek V, Mlejnek P, Simáková M, Silhavy J, Landa V, Kazdová L, Pravenec M, Kurtz TW.

Am J Hypertens. 2013 Jun;26(6):829-35. doi: 10.1093/ajh/hpt019. Epub 2013 Feb 20.

PMID:
23426788
[PubMed - indexed for MEDLINE]
18.

Folate deficiency is associated with oxidative stress, increased blood pressure, and insulin resistance in spontaneously hypertensive rats.

Pravenec M, Kozich V, Krijt J, Sokolová J, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Oliyarnyk O, Kazdová L, Kurtz TW.

Am J Hypertens. 2013 Jan;26(1):135-40. doi: 10.1093/ajh/hps015.

PMID:
23382337
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat.

Mancini M, Petretto E, Kleinert C, Scavone A, De T, Cook S, Silhavy J, Zidek V, Pravenec M, d'Amati G, Camici PG.

Basic Res Cardiol. 2013 Jan;108(1):316. doi: 10.1007/s00395-012-0316-y. Epub 2012 Nov 30.

PMID:
23197152
[PubMed - indexed for MEDLINE]
20.

Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits.

Katter K, Geurts AM, Hoffmann O, Mátés L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, Grzybowksi M, Corbett M, Filho AR, Hodges MR, Bader M, Ivics Z, Jacob HJ, Pravenec M, Bosze Z, Rülicke T, Izsvák Z.

FASEB J. 2013 Mar;27(3):930-41. doi: 10.1096/fj.12-205526. Epub 2012 Nov 29.

PMID:
23195032
[PubMed - indexed for MEDLINE]
Free PMC Article

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