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Results: 1 to 20 of 181

1.

Sterol regulatory element binding protein 2 overexpression is associated with reduced adipogenesis and ectopic fat accumulation in transgenic spontaneously hypertensive rats.

Landa V, Zídek V, Mlejnek P, Simáková M, Silhavý J, Trnovská J, Kazdová L, Pravenec M.

Physiol Res. 2014 Jun 5. [Epub ahead of print]

PMID:
24908080
[PubMed - as supplied by publisher]
Free Article
2.

Natural variation of histone modification and its impact on gene expression in the rat genome.

Rintisch C, Heinig M, Bauerfeind A, Schafer S, Mieth C, Patone G, Hummel O, Chen W, Cook S, Cuppen E, Colomé-Tatché M, Johannes F, Jansen RC, Neil H, Werner M, Pravenec M, Vingron M, Hubner N.

Genome Res. 2014 Jun;24(6):942-53. doi: 10.1101/gr.169029.113. Epub 2014 May 2.

PMID:
24793478
[PubMed - in process]
3.

Pharmacogenetic analysis of captopril effects on blood pressure: possible role of the Ednrb (endothelin receptor type B) candidate gene.

Zicha J, Dobešová Z, Zídek V, Silhavý J, Simáková M, Mlejnek P, Vaněčková I, Kuneš J, Pravenec M.

Physiol Res. 2014;63(2):263-5.

PMID:
24779608
[PubMed - in process]
Free Article
4.

Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons.

Ivics Z, Garrels W, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Kues WA, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):810-27. doi: 10.1038/nprot.2014.010. Epub 2014 Mar 13.

PMID:
24625780
[PubMed - in process]
5.

Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons.

Ivics Z, Hiripi L, Hoffmann OI, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Bösze Z, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):794-809. doi: 10.1038/nprot.2014.009. Epub 2014 Mar 13.

PMID:
24625779
[PubMed - in process]
6.

Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons.

Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z.

Nat Protoc. 2014 Apr;9(4):773-93. doi: 10.1038/nprot.2014.008. Epub 2014 Mar 13.

PMID:
24625778
[PubMed - in process]
7.

Recent progress in the genetics of spontaneously hypertensive rats.

Pravenec M, Křen V, Landa V, Mlejnek P, Musilová A, Šilhavý J, Šimáková M, Zídek V.

Physiol Res. 2014;63 Suppl 1:S1-8.

PMID:
24564651
[PubMed - in process]
Free Article
8.

Rosuvastatin can block pro-inflammatory actions of transgenic human C-reactive protein without reducing its circulating levels.

Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Škop V, Oliyarnyk O, Kazdová L, Mancini M, Saar K, Schulz H, Hübner N, Kurtz TW, Pravenec M.

Cardiovasc Ther. 2014 Apr;32(2):59-65. doi: 10.1111/1755-5922.12061.

PMID:
24410968
[PubMed - in process]
9.

Plzf as a candidate gene predisposing the spontaneously hypertensive rat to hypertension, left ventricular hypertrophy, and interstitial fibrosis.

Liška F, Mancini M, Krupková M, Chylíková B, Křenová D, Šeda O, Šilhavý J, Mlejnek P, Landa V, Zídek V, d' Amati G, Pravenec M, Křen V.

Am J Hypertens. 2014 Jan;27(1):99-106. doi: 10.1093/ajh/hpt156. Epub 2013 Aug 23.

PMID:
23975223
[PubMed - in process]
10.

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension.

Friese RS, Altshuler AE, Zhang K, Miramontes-Gonzalez JP, Hightower CM, Jirout ML, Salem RM, Gayen JR, Mahapatra NR, Biswas N, Cale M, Vaingankar SM, Kim HS, Courel M, Taupenot L, Ziegler MG, Schork NJ, Pravenec M, Mahata SK, Schmid-Schönbein GW, O'Connor DT.

Hum Mol Genet. 2013 Sep 15;22(18):3624-40. doi: 10.1093/hmg/ddt213. Epub 2013 May 13.

PMID:
23674521
[PubMed - indexed for MEDLINE]
11.

Transgenic rescue of defective Cd36 enhances myocardial adenylyl cyclase signaling in spontaneously hypertensive rats.

Klevstig M, Manakov D, Kasparova D, Brabcova I, Papousek F, Zurmanova J, Zidek V, Silhavy J, Neckar J, Pravenec M, Kolar F, Novakova O, Novotny J.

Pflugers Arch. 2013 Oct;465(10):1477-86. doi: 10.1007/s00424-013-1281-5. Epub 2013 May 1.

PMID:
23636771
[PubMed - indexed for MEDLINE]
12.

Tissue-specific peroxisome proliferator activated receptor gamma expression and metabolic effects of telmisartan.

Zídek V, Mlejnek P, Simáková M, Silhavy J, Landa V, Kazdová L, Pravenec M, Kurtz TW.

Am J Hypertens. 2013 Jun;26(6):829-35. doi: 10.1093/ajh/hpt019. Epub 2013 Feb 20.

PMID:
23426788
[PubMed - indexed for MEDLINE]
13.

Folate deficiency is associated with oxidative stress, increased blood pressure, and insulin resistance in spontaneously hypertensive rats.

Pravenec M, Kozich V, Krijt J, Sokolová J, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Oliyarnyk O, Kazdová L, Kurtz TW.

Am J Hypertens. 2013 Jan;26(1):135-40. doi: 10.1093/ajh/hps015.

PMID:
23382337
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat.

Mancini M, Petretto E, Kleinert C, Scavone A, De T, Cook S, Silhavy J, Zidek V, Pravenec M, d'Amati G, Camici PG.

Basic Res Cardiol. 2013 Jan;108(1):316. doi: 10.1007/s00395-012-0316-y. Epub 2012 Nov 30.

PMID:
23197152
[PubMed - indexed for MEDLINE]
15.

Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits.

Katter K, Geurts AM, Hoffmann O, Mátés L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, Grzybowksi M, Corbett M, Filho AR, Hodges MR, Bader M, Ivics Z, Jacob HJ, Pravenec M, Bosze Z, Rülicke T, Izsvák Z.

FASEB J. 2013 Mar;27(3):930-41. doi: 10.1096/fj.12-205526. Epub 2012 Nov 29.

PMID:
23195032
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans.

Langley SR, Bottolo L, Kunes J, Zicha J, Zidek V, Hubner N, Cook SA, Pravenec M, Aitman TJ, Petretto E.

Cardiovasc Res. 2013 Mar 15;97(4):653-65. doi: 10.1093/cvr/cvs329. Epub 2012 Oct 31.

PMID:
23118132
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

Simonis M, Atanur SS, Linsen S, Guryev V, Ruzius FP, Game L, Lansu N, de Bruijn E, van Heesch S, Jones SJ, Pravenec M, Aitman TJ, Cuppen E.

Genome Biol. 2012 Apr 27;13(4):r31. doi: 10.1186/gb-2012-13-4-r31.

PMID:
22541052
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains.

Houštek J, Hejzlarová K, Vrbacký M, Drahota Z, Landa V, Zídek V, Mlejnek P, Šimáková M, Šilhavy J, Mikšík I, Kazdová L, Oliyarnyk O, Kurtz T, Pravenec M.

Physiol Genomics. 2012 May 1;44(9):487-94. doi: 10.1152/physiolgenomics.00156.2011. Epub 2012 Mar 13.

PMID:
22414913
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis.

Neckář J, Šilhavy J, Zídek V, Landa V, Mlejnek P, Šimáková M, Seidman JG, Seidman C, Kazdová L, Klevstig M, Novák F, Vecka M, Papoušek F, Houštěk J, Drahota Z, Kurtz TW, Kolář F, Pravenec M.

Physiol Genomics. 2012 Feb 1;44(2):173-82. doi: 10.1152/physiolgenomics.00083.2011. Epub 2011 Nov 29.

PMID:
22128087
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

McDermott-Roe C, Ye J, Ahmed R, Sun XM, Serafín A, Ware J, Bottolo L, Muckett P, Cañas X, Zhang J, Rowe GC, Buchan R, Lu H, Braithwaite A, Mancini M, Hauton D, Martí R, García-Arumí E, Hubner N, Jacob H, Serikawa T, Zidek V, Papousek F, Kolar F, Cardona M, Ruiz-Meana M, García-Dorado D, Comella JX, Felkin LE, Barton PJ, Arany Z, Pravenec M, Petretto E, Sanchis D, Cook SA.

Nature. 2011 Oct 5;478(7367):114-8. doi: 10.1038/nature10490.

PMID:
21979051
[PubMed - indexed for MEDLINE]
Free PMC Article

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