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Results: 1 to 20 of 264

1.

Population and single cell genomics reveal the Aire-dependency, relief from Polycomb silencing and distribution of self-antigen expression in thymic epithelia.

Sansom SN, Shikama N, Zhanybekova S, Nusspaumer G, Macaulay IC, Deadman ME, Heger A, Ponting CP, Holländer GA.

Genome Res. 2014 Sep 15. pii: gr.171645.113. [Epub ahead of print]

PMID:
25224068
[PubMed - as supplied by publisher]
Free Article
2.

Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype.

Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnár Z, Ponting CP.

Cereb Cortex. 2014 Sep 10. pii: bhu196. [Epub ahead of print]

PMID:
25209608
[PubMed - as supplied by publisher]
Free Article
3.

The genomic substrate for adaptive radiation in African cichlid fish.

Brawand D, Wagner CE, Li YI, Malinsky M, Keller I, Fan S, Simakov O, Ng AY, Lim ZW, Bezault E, Turner-Maier J, Johnson J, Alcazar R, Noh HJ, Russell P, Aken B, Alföldi J, Amemiya C, Azzouzi N, Baroiller JF, Barloy-Hubler F, Berlin A, Bloomquist R, Carleton KL, Conte MA, D'Cotta H, Eshel O, Gaffney L, Galibert F, Gante HF, Gnerre S, Greuter L, Guyon R, Haddad NS, Haerty W, Harris RM, Hofmann HA, Hourlier T, Hulata G, Jaffe DB, Lara M, Lee AP, MacCallum I, Mwaiko S, Nikaido M, Nishihara H, Ozouf-Costaz C, Penman DJ, Przybylski D, Rakotomanga M, Renn SC, Ribeiro FJ, Ron M, Salzburger W, Sanchez-Pulido L, Santos ME, Searle S, Sharpe T, Swofford R, Tan FJ, Williams L, Young S, Yin S, Okada N, Kocher TD, Miska EA, Lander ES, Venkatesh B, Fernald RD, Meyer A, Ponting CP, Streelman JT, Lindblad-Toh K, Seehausen O, Di Palma F.

Nature. 2014 Sep 18;513(7518):375-81. doi: 10.1038/nature13726. Epub 2014 Sep 3.

PMID:
25186727
[PubMed - in process]
4.

Understanding functional miRNA-target interactions in vivo by site-specific genome engineering.

Bassett AR, Azzam G, Wheatley L, Tibbit C, Rajakumar T, McGowan S, Stanger N, Ewels PA, Taylor S, Ponting CP, Liu JL, Sauka-Spengler T, Fulga TA.

Nat Commun. 2014 Aug 19;5:4640. doi: 10.1038/ncomms5640.

PMID:
25135198
[PubMed - in process]
Free PMC Article
5.

Considerations when investigating lncRNA function in vivo.

Bassett AR, Akhtar A, Barlow DP, Bird AP, Brockdorff N, Duboule D, Ephrussi A, Ferguson-Smith AC, Gingeras TR, Haerty W, Higgs DR, Miska EA, Ponting CP.

Elife. 2014 Aug 14;3:e03058. doi: 10.7554/eLife.03058.

PMID:
25124674
[PubMed - in process]
Free PMC Article
6.

The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast.

White SA, Buscaino A, Sanchez-Pulido L, Ponting CP, Nowicki MW, Allshire RC.

PLoS One. 2014 Aug 4;9(8):e104161. doi: 10.1371/journal.pone.0104161. eCollection 2014.

PMID:
25090107
[PubMed - in process]
Free PMC Article
7.

8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.

Rands CM, Meader S, Ponting CP, Lunter G.

PLoS Genet. 2014 Jul 24;10(7):e1004525. doi: 10.1371/journal.pgen.1004525. eCollection 2014 Jul.

PMID:
25057982
[PubMed - in process]
Free PMC Article
8.

Transcriptional regulatory functions of nuclear long noncoding RNAs.

Vance KW, Ponting CP.

Trends Genet. 2014 Aug;30(8):348-55. doi: 10.1016/j.tig.2014.06.001. Epub 2014 Jun 25.

PMID:
24974018
[PubMed - in process]
Free PMC Article
9.

Diagnostically relevant facial gestalt information from ordinary photos.

Ferry Q, Steinberg J, Webber C, FitzPatrick DR, Ponting CP, Zisserman A, Nellåker C.

Elife. 2014 Jun 24;3:e02020. doi: 10.7554/eLife.02020.

PMID:
24963138
[PubMed - in process]
Free PMC Article
10.

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.

Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A; UK10K; Baylor-Hopkins Center for Mendelian Genomics, Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR.

Am J Hum Genet. 2014 Jun 5;94(6):915-23. doi: 10.1016/j.ajhg.2014.05.005.

PMID:
24906020
[PubMed - indexed for MEDLINE]
11.

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery.

Booth DG, Takagi M, Sanchez-Pulido L, Petfalski E, Vargiu G, Samejima K, Imamoto N, Ponting CP, Tollervey D, Earnshaw WC, Vagnarelli P.

Elife. 2014 May 27;3:e01641. doi: 10.7554/eLife.01641.

PMID:
24867636
[PubMed - in process]
Free PMC Article
12.

A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.

Lu M, Zak J, Chen S, Sanchez-Pulido L, Severson DT, Endicott J, Ponting CP, Schofield CJ, Lu X.

Cell. 2014 May 22;157(5):1130-45. doi: 10.1016/j.cell.2014.05.006.

PMID:
24855949
[PubMed - indexed for MEDLINE]
13.

Intergenic lncRNAs and the evolution of gene expression.

Marques AC, Ponting CP.

Curr Opin Genet Dev. 2014 Aug;27:48-53. doi: 10.1016/j.gde.2014.03.009. Epub 2014 May 21.

PMID:
24852186
[PubMed - in process]
14.

No gene in the genome makes sense except in the light of evolution.

Haerty W, Ponting CP.

Annu Rev Genomics Hum Genet. 2014 Aug 31;15:71-92. doi: 10.1146/annurev-genom-090413-025621. Epub 2014 Apr 24.

PMID:
24773316
[PubMed - in process]
15.

Brain-expressed 3'UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs.

Wehrspaun CC, Ponting CP, Marques AC.

Front Genet. 2014 Feb 26;5:41. doi: 10.3389/fgene.2014.00041. eCollection 2014.

PMID:
24616735
[PubMed]
Free PMC Article
16.

The long non-coding RNA Paupar regulates the expression of both local and distal genes.

Vance KW, Sansom SN, Lee S, Chalei V, Kong L, Cooper SE, Oliver PL, Ponting CP.

EMBO J. 2014 Feb 18;33(4):296-311. doi: 10.1002/embj.201386225. Epub 2014 Feb 1.

PMID:
24488179
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sequencing depth and coverage: key considerations in genomic analyses.

Sims D, Sudbery I, Ilott NE, Heger A, Ponting CP.

Nat Rev Genet. 2014 Feb;15(2):121-32. doi: 10.1038/nrg3642. Review.

PMID:
24434847
[PubMed - indexed for MEDLINE]
18.

CGAT: computational genomics analysis toolkit.

Sims D, Ilott NE, Sansom SN, Sudbery IM, Johnson JS, Fawcett KA, Berlanga-Taylor AJ, Luna-Valero S, Ponting CP, Heger A.

Bioinformatics. 2014 May 1;30(9):1290-1. doi: 10.1093/bioinformatics/btt756. Epub 2014 Jan 5.

PMID:
24395753
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9.

Bassett AR, Tibbit C, Ponting CP, Liu JL.

Biol Open. 2014 Jan 15;3(1):42-9. doi: 10.1242/bio.20137120.

PMID:
24326186
[PubMed]
Free PMC Article
20.

Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs.

Marques AC, Hughes J, Graham B, Kowalczyk MS, Higgs DR, Ponting CP.

Genome Biol. 2013 Nov 29;14(11):R131. doi: 10.1186/gb-2013-14-11-r131.

PMID:
24289259
[PubMed - in process]
Free PMC Article

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