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R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.


Decomposing genomic variance using information from GWA, GWE and eQTL analysis.

Ehsani A, Janss L, Pomp D, Sørensen P.

Anim Genet. 2016 Apr;47(2):165-73. doi: 10.1111/age.12396. Epub 2015 Dec 17.


The 'Omics' of Voluntary Exercise: Systems Approaches to a Complex Phenotype.

Kelly SA, Villena FP, Pomp D.

Trends Endocrinol Metab. 2015 Dec;26(12):673-5. doi: 10.1016/j.tem.2015.10.002. Epub 2015 Nov 6.


Maternal exercise before and during pregnancy does not impact offspring exercise or body composition in mice.

Kelly SA, Hua K, Wallace JN, Wells SE, Nehrenberg DL, Pomp D.

J Negat Results Biomed. 2015 Aug 3;14:13. doi: 10.1186/s12952-015-0032-x.


A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.


Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Nietfeldt J, Legge RM, Ma F, Hua K, Sinha R, Peterson DA, Walter J, Benson AK, Pomp D.

Genome Biol. 2014;15(12):552.


High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis.

Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ.

G3 (Bethesda). 2014 Oct 23;4(12):2353-63. doi: 10.1534/g3.114.014704.


Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.


Quantitative genomics of voluntary exercise in mice: transcriptional analysis and mapping of expression QTL in muscle.

Kelly SA, Nehrenberg DL, Hua K, Garland T Jr, Pomp D.

Physiol Genomics. 2014 Aug 15;46(16):593-601. doi: 10.1152/physiolgenomics.00023.2014. Epub 2014 Jun 17.


Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss.

Leamy LJ, Elo K, Nielsen MK, Thorn SR, Valdar W, Pomp D.

PeerJ. 2014 May 27;2:e392. doi: 10.7717/peerj.392. eCollection 2014.


A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice.

Kelly SA, Bell TA, Selitsky SR, Buus RJ, Hua K, Weinstock GM, Garland T Jr, Pardo-Manuel de Villena F, Pomp D.

Genetics. 2013 Dec;195(4):1385-95. doi: 10.1534/genetics.113.154476. Epub 2013 Sep 20.


Quantitative trait loci for bone mineral density and femoral morphology in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Hua K, Farber CR, Pomp D.

Bone. 2013 Jul;55(1):222-9. doi: 10.1016/j.bone.2013.02.014. Epub 2013 Feb 26.


Genetic determinants of voluntary exercise.

Kelly SA, Pomp D.

Trends Genet. 2013 Jun;29(6):348-57. doi: 10.1016/j.tig.2012.12.007. Epub 2013 Jan 23. Review.


Exercise and diet affect quantitative trait loci for body weight and composition traits in an advanced intercross population of mice.

Leamy LJ, Kelly SA, Hua K, Pomp D.

Physiol Genomics. 2012 Dec 1;44(23):1141-53. doi: 10.1152/physiolgenomics.00115.2012. Epub 2012 Oct 9.


Inferring genetic architecture of complex traits using Bayesian integrative analysis of genome and transcriptome data.

Ehsani A, Sørensen P, Pomp D, Allan M, Janss L.

BMC Genomics. 2012 Sep 5;13:456. doi: 10.1186/1471-2164-13-456.


Functional genomic architecture of predisposition to voluntary exercise in mice: expression QTL in the brain.

Kelly SA, Nehrenberg DL, Hua K, Garland T Jr, Pomp D.

Genetics. 2012 Jun;191(2):643-54. doi: 10.1534/genetics.112.140509. Epub 2012 Mar 30.


Sex-, diet-, and cancer-dependent epistatic effects on complex traits in mice.

Leamy LJ, Gordon RR, Pomp D.

Front Genet. 2011 Oct 28;2:71. doi: 10.3389/fgene.2011.00071. eCollection 2011.


Advances in comparative genetics: influence of genetics on obesity.

Mathes WF, Kelly SA, Pomp D.

Br J Nutr. 2011 Oct;106 Suppl 1:S1-10. doi: 10.1017/S0007114511001905. Review.


Epistatic interactions of genes influence within-individual variation of physical activity traits in mice.

Leamy LJ, Pomp D, Lightfoot JT.

Genetica. 2011 Jun;139(6):813-21. doi: 10.1007/s10709-011-9586-9. Epub 2011 Jun 11.

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