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Results: 1 to 20 of 133

1.

Interaction Between Domperidone and Ketoconazole: Toward Prediction of Consequent QTc Prolongation Using Purely In Vitro Information.

Mishra H, Polak S, Jamei M, Rostami-Hodjegan A.

CPT Pharmacometrics Syst Pharmacol. 2014 Aug 13;3:e130. doi: 10.1038/psp.2014.26.

PMID:
25116274
[PubMed]
Free PMC Article
2.

Induced pluripotent stem cells and their implication for regenerative medicine.

Csobonyeiova M, Polak S, Koller J, Danisovic L.

Cell Tissue Bank. 2014 Jul 19. [Epub ahead of print]

PMID:
25037593
[PubMed - as supplied by publisher]
3.

[New views on the functional morphology of human clitoris].

Miko M, Urban L, Kajanová M, Polák S, Varga I.

Ceska Gynekol. 2014 Apr;79(2):147-55. Czech.

PMID:
24874830
[PubMed - in process]
4.

Computer-based prediction of the drug proarrhythmic effect: problems, issues, known and suspected challenges.

Wiśniowska B, Mendyk A, Fijorek K, Polak S.

Europace. 2014 May;16(5):724-35. doi: 10.1093/europace/euu009.

PMID:
24798962
[PubMed - in process]
5.

Model of the distribution of diastolic left ventricular posterior wall thickness in healthy adults and its impact on the behavior of a string of virtual cardiomyocytes.

Fijorek K, Tanner FC, Stähli BE, Gielerak G, Krzesinski P, Uzieblo-Zyczkowska B, Smurzynski P, Stanczyk A, Stolarz-Skrzypek K, Kawecka-Jaszcz K, Jastrzebski M, Podolec M, Kopec G, Stanula B, Kocowska M, Tylutki Z, Polak S.

J Cardiovasc Transl Res. 2014 Jul;7(5):507-17. doi: 10.1007/s12265-014-9558-4. Epub 2014 Mar 28.

PMID:
24676501
[PubMed - in process]
Free PMC Article
6.

The effects of six antipsychotic agents on QTc--an attempt to mimic clinical trial through simulation including variability in the population.

Glinka A, Polak S.

Comput Biol Med. 2014 Apr;47:20-6. doi: 10.1016/j.compbiomed.2014.01.010. Epub 2014 Jan 28.

PMID:
24530535
[PubMed - in process]
7.

In vitro-in vivo extrapolation of drug-induced proarrhythmia predictions at the population level.

Polak S, Wiśniowska B, Fijorek K, Glinka A, Mendyk A.

Drug Discov Today. 2014 Mar;19(3):275-81. doi: 10.1016/j.drudis.2013.10.009. Epub 2013 Oct 16.

PMID:
24140591
[PubMed - in process]
8.

Circadian models of serum potassium, sodium, and calcium concentrations in healthy individuals and their application to cardiac electrophysiology simulations at individual level.

Fijorek K, Puskulluoglu M, Polak S.

Comput Math Methods Med. 2013;2013:429037. doi: 10.1155/2013/429037. Epub 2013 Sep 3.

PMID:
24078832
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Quantitative prediction of formulation-specific food effects and their population variability from in vitro data with the physiologically-based ADAM model: a case study using the BCS/BDDCS Class II drug nifedipine.

Patel N, Polak S, Jamei M, Rostami-Hodjegan A, Turner DB.

Eur J Pharm Sci. 2014 Jun 16;57:240-9. doi: 10.1016/j.ejps.2013.09.006. Epub 2013 Sep 21.

PMID:
24060671
[PubMed - in process]
10.

PID controller auto-tuning based on process step response and damping optimum criterion.

Pavković D, Polak S, Zorc D.

ISA Trans. 2014 Jan;53(1):85-96. doi: 10.1016/j.isatra.2013.08.011. Epub 2013 Sep 12.

PMID:
24035643
[PubMed]
11.

In vitro to human in vivo translation - pharmacokinetics and pharmacodynamics of quinidine.

Polak S.

ALTEX. 2013;30(3):309-18.

PMID:
23861085
[PubMed - indexed for MEDLINE]
Free Article
12.

The normal human newborns thymus.

Jablonska-Mestanova V, Sisovsky V, Danisovic L, Polak S, Varga I.

Bratisl Lek Listy. 2013;114(7):402-8.

PMID:
23822626
[PubMed - indexed for MEDLINE]
13.

A mechanism for effective cell-seeding in rigid, microporous substrates.

Polak SJ, Rustom LE, Genin GM, Talcott M, Wagoner Johnson AJ.

Acta Biomater. 2013 Aug;9(8):7977-86. doi: 10.1016/j.actbio.2013.04.040. Epub 2013 May 9.

PMID:
23665116
[PubMed - indexed for MEDLINE]
14.

Generalized in vitro-in vivo relationship (IVIVR) model based on artificial neural networks.

Mendyk A, Tuszyński PK, Polak S, Jachowicz R.

Drug Des Devel Ther. 2013;7:223-32. doi: 10.2147/DDDT.S41401. Epub 2013 Mar 27.

PMID:
23569360
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Age and gender dependent heart rate circadian model development and performance verification on the proarrhythmic drug case study.

Fijorek K, Patel N, Klima Ł, Stolarz-Skrzypek K, Kawecka-Jaszcz K, Polak S.

Theor Biol Med Model. 2013 Feb 9;10:7. doi: 10.1186/1742-4682-10-7.

PMID:
23394137
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Wild type and K897T polymorphisms of the hERG gene: modeling the APD in Caucasians.

Glinka A, Polak S.

Bioinformation. 2012;8(22):1062-5. doi: 10.6026/97320630081062. Epub 2012 Nov 13.

PMID:
23251039
[PubMed]
Free PMC Article
17.

A mixed-methods assessment of sexual and gender-based violence in eastern Democratic Republic of Congo to inform national and international strategy implementation.

Scott J, Polak S, Kisielewski M, McGraw-Gross M, Johnson K, Hendrickson M, Lawry L.

Int J Health Plann Manage. 2013 Jul-Sep;28(3):e188-216. doi: 10.1002/hpm.2144. Epub 2012 Oct 29.

PMID:
23108942
[PubMed - indexed for MEDLINE]
18.

Tox-database.net: a curated resource for data describing chemical triggered in vitro cardiac ion channels inhibition.

Polak S, Wiśniowska B, Glinka A, Polak M.

BMC Pharmacol Toxicol. 2012 Aug 13;13:6. doi: 10.1186/2050-6511-13-6.

PMID:
22947121
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.

Wiśniowska B, Mendyk A, Fijorek K, Glinka A, Polak S.

J Appl Toxicol. 2012 Oct;32(10):858-66. doi: 10.1002/jat.2784. Epub 2012 Jul 3.

PMID:
22761000
[PubMed - indexed for MEDLINE]
20.

Prediction of concentration-time profile and its inter-individual variability following the dermal drug absorption.

Polak S, Ghobadi C, Mishra H, Ahamadi M, Patel N, Jamei M, Rostami-Hodjegan A.

J Pharm Sci. 2012 Jul;101(7):2584-95. doi: 10.1002/jps.23155. Epub 2012 Apr 19.

PMID:
22517028
[PubMed - indexed for MEDLINE]

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