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Items: 1 to 20 of 69


Multiple sclerosis masquerading as Alzheimer-type dementia: Clinical, radiological and pathological findings.

Tobin WO, Popescu BF, Lowe V, Pirko I, Parisi JE, Kantarci K, Fields JA, Bruns MB, Boeve BF, Lucchinetti CF.

Mult Scler. 2015 Oct 7. pii: 1352458515604382. [Epub ahead of print]


Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque.

Frischer JM, Weigand SD, Guo Y, Kale N, Parisi JE, Pirko I, Mandrekar J, Bramow S, Metz I, Brück W, Lassmann H, Lucchinetti CF.

Ann Neurol. 2015 Aug 3. doi: 10.1002/ana.24497. [Epub ahead of print]


Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis.

Novotna M, Paz Soldán MM, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M, Kantarci OH.

Neurology. 2015 Aug 25;85(8):722-9. doi: 10.1212/WNL.0000000000001856. Epub 2015 Jul 24.


Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses.

Renner DN, Jin F, Litterman AJ, Balgeman AJ, Hanson LM, Gamez JD, Chae M, Carlson BL, Sarkaria JN, Parney IF, Ohlfest JR, Pirko I, Pavelko KD, Johnson AJ.

PLoS One. 2015 May 1;10(5):e0125565. doi: 10.1371/journal.pone.0125565. eCollection 2015.


Correlation of Brain Atrophy, Disability, and Spinal Cord Atrophy in a Murine Model of Multiple Sclerosis.

Paz Soldán MM, Raman MR, Gamez JD, Lohrey AK, Chen Y, Pirko I, Johnson AJ.

J Neuroimaging. 2015 Jul-Aug;25(4):595-9. doi: 10.1111/jon.12250. Epub 2015 Apr 20.


Relapses and disability accumulation in progressive multiple sclerosis.

Paz Soldán MM, Novotna M, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Weinshenker BG, Rodriguez M, Kantarci OH.

Neurology. 2015 Jan 6;84(1):81-8. doi: 10.1212/WNL.0000000000001094. Epub 2014 Nov 14.


Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption.

Johnson HL, Willenbring RC, Jin F, Manhart WA, LaFrance SJ, Pirko I, Johnson AJ.

PLoS One. 2014 Oct 22;9(10):e111401. doi: 10.1371/journal.pone.0111401. eCollection 2014.


[cDNA library construction from panicle meristem of finger millet].

Radchuk V, Pirko IaV, Isaenkov SV, Emets AI, Blium IaB.

Tsitol Genet. 2014 Sep-Oct;48(5):3-10. Russian.


MR microscopy of formalin fixed paraffin embedded histology specimens.

Macura S, Mishra PK, Gamez JD, Pirko I.

Magn Reson Med. 2014 Jun;71(6):1989-94. doi: 10.1002/mrm.25225. Epub 2014 Apr 8.


Novel immunomodulatory approaches for the management of multiple sclerosis.

Kantarci OH, Pirko I, Rodriguez M.

Clin Pharmacol Ther. 2014 Jan;95(1):32-44. doi: 10.1038/clpt.2013.196. Epub 2013 Oct 30. Review.


Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption.

Johnson HL, Hanson LM, Chen Y, Bieber AJ, Buono RJ, Ferraro TN, Pirko I, Johnson AJ.

BMC Genomics. 2013 Oct 3;14:678. doi: 10.1186/1471-2164-14-678.


Pathology of multiple sclerosis: where do we stand?

Popescu BF, Pirko I, Lucchinetti CF.

Continuum (Minneap Minn). 2013 Aug;19(4 Multiple Sclerosis):901-21. doi: 10.1212/01.CON.0000433291.23091.65. Review.


Neuroradiological evaluation of demyelinating disease.

Tillema JM, Pirko I.

Ther Adv Neurol Disord. 2013 Jul;6(4):249-68. doi: 10.1177/1756285613478870.


Theiler's murine encephalomyelitis virus as an experimental model system to study the mechanism of blood-brain barrier disruption.

Johnson HL, Jin F, Pirko I, Johnson AJ.

J Neurovirol. 2014 Apr;20(2):107-12. doi: 10.1007/s13365-013-0187-5. Epub 2013 Jul 16. Review.


The thalamus and multiple sclerosis: modern views on pathologic, imaging, and clinical aspects.

Minagar A, Barnett MH, Benedict RH, Pelletier D, Pirko I, Sahraian MA, Frohman E, Zivadinov R.

Neurology. 2013 Jan 8;80(2):210-9. doi: 10.1212/WNL.0b013e31827b910b. Review.


Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability.

Suidan GL, Dickerson JW, Johnson HL, Chan TW, Pavelko KD, Pirko I, Seroogy KB, Johnson AJ.

J Neuroinflammation. 2012 Sep 18;9:218. doi: 10.1186/1742-2094-9-218.


Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders.

Lee MR, Denic A, Hinton DJ, Mishra PK, Choi DS, Pirko I, Rodriguez M, Macura SI.

Bioanalysis. 2012 Jul;4(14):1787-804. doi: 10.4155/BIO.12.129. Review.


CD8 T cell-initiated blood-brain barrier disruption is independent of neutrophil support.

Johnson HL, Chen Y, Jin F, Hanson LM, Gamez JD, Pirko I, Johnson AJ.

J Immunol. 2012 Aug 15;189(4):1937-45. doi: 10.4049/jimmunol.1200658. Epub 2012 Jul 6.


Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis.

Tutuncu M, Tang J, Zeid NA, Kale N, Crusan DJ, Atkinson EJ, Siva A, Pittock SJ, Pirko I, Keegan BM, Lucchinetti CF, Noseworthy JH, Rodriguez M, Weinshenker BG, Kantarci OH.

Mult Scler. 2013 Feb;19(2):188-98. doi: 10.1177/1352458512451510. Epub 2012 Jun 26.


Non-lesional white matter changes in pediatric multiple sclerosis and monophasic demyelinating disorders.

Tillema JM, Leach J, Pirko I.

Mult Scler. 2012 Dec;18(12):1754-9. doi: 10.1177/1352458512447527. Epub 2012 May 28.

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