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The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data.

WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group, Adjuik MA, Allan R, Anvikar AR, Ashley EA, Ba MS, Barennes H, Barnes KI, Bassat Q, Baudin E, Björkman A, Bompart F, Bonnet M, Borrmann S, Brasseur P, Bukirwa H, Checchi F, Cot M, Dahal P, D'Alessandro U, Deloron P, Desai M, Diap G, Djimde AA, Dorsey G, Doumbo OK, Espié E, Etard JF, Fanello CI, Faucher JF, Faye B, Flegg JA, Gaye O, Gething PW, González R, Grandesso F, Guerin PJ, Guthmann JP, Hamour S, Hasugian AR, Hay SI, Humphreys GS, Jullien V, Juma E, Kamya MR, Karema C, Kiechel JR, Kremsner PG, Krishna S, Lameyre V, Ibrahim LM, Lee SJ, Lell B, Mårtensson A, Massougbodji A, Menan H, Ménard D, Menéndez C, Meremikwu M, Moreira C, Nabasumba C, Nambozi M, Ndiaye JL, Nikiema F, Nsanzabana C, Ntoumi F, Ogutu BR, Olliaro P, Osorio L, Ouédraogo JB, Penali LK, Pene M, Pinoges L, Piola P, Price RN, Roper C, Rosenthal PJ, Rwagacondo CE, Same-Ekobo A, Schramm B, Seck A, Sharma B, Sibley CH, Sinou V, Sirima SB, Smith JJ, Smithuis F, Somé FA, Sow D, Staedke SG, Stepniewska K, Swarthout TD, Sylla K, Talisuna AO, Tarning J, Taylor WR, Temu EA, Thwing JI, Tjitra E, Tine RC, Tinto H, Vaillant MT, Valecha N, Van den Broek I, White NJ, Yeka A, Zongo I.

BMC Med. 2015 Mar 31;13:66. doi: 10.1186/s12916-015-0301-z.


Risk factors and mortality associated with resistance to first-line antiretroviral therapy: multicentric cross-sectional and longitudinal analyses.

Pinoges L, Schramm B, Poulet E, Balkan S, Szumilin E, Ferreyra C, Pujades-Rodríguez M.

J Acquir Immune Defic Syndr. 2015 Apr 15;68(5):527-35. doi: 10.1097/QAI.0000000000000513.


Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority trial.

Schramm B, Valeh P, Baudin E, Mazinda CS, Smith R, Pinoges L, Dhorda M, Boum Y 2nd, Sundaygar T, Zolia YM, Jones JJ, Comte E, Houzé P, Jullien V, Carn G, Kiechel JR, Ashley EA, Guérin PJ.

Malar J. 2013 Jul 17;12:251. doi: 10.1186/1475-2875-12-251.


Tolerability and safety of artesunate-amodiaquine and artemether-lumefantrine fixed dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria: two open-label, randomized trials in Nimba County, Liberia.

Schramm B, Valeh P, Baudin E, Mazinda CS, Smith R, Pinoges L, Sundaygar T, Zolia YM, Jones JJ, Comte E, Bruneel A, Branger M, Jullien V, Carn G, Kiechel JR, Ashley EA, Guérin PJ.

Malar J. 2013 Jul 17;12:250. doi: 10.1186/1475-2875-12-250.


Timeliness of clinic attendance is a good predictor of virological response and resistance to antiretroviral drugs in HIV-infected patients.

Bastard M, Pinoges L, Balkan S, Szumilin E, Ferreyra C, Pujades-Rodriguez M.

PLoS One. 2012;7(11):e49091. doi: 10.1371/journal.pone.0049091. Epub 2012 Nov 7.


Treatment initiation, program attrition and patient treatment outcomes associated with scale-up and decentralization of HIV care in rural Malawi.

McGuire M, Pinoges L, Kanapathipillai R, Munyenyembe T, Huckabee M, Makombe S, Szumilin E, Heinzelmann A, Pujades-Rodríguez M.

PLoS One. 2012;7(10):e38044. doi: 10.1371/journal.pone.0038044. Epub 2012 Oct 15.


Gender differences in immune reconstitution: a multicentric cohort analysis in sub-Saharan Africa.

Maman D, Pujades-Rodriguez M, Subtil F, Pinoges L, McGuire M, Ecochard R, Etard JF.

PLoS One. 2012;7(2):e31078. doi: 10.1371/journal.pone.0031078. Epub 2012 Feb 17.


Toxicity associated with stavudine dose reduction from 40 to 30 mg in first-line antiretroviral therapy.

Pujades-Rodríguez M, Dantony E, Pinoges L, Ecochard R, Etard JF, Carrillo-Casas E, Szumilin E; AIDS Working Group of Médecins Sans Frontières.

PLoS One. 2011;6(11):e28112. doi: 10.1371/journal.pone.0028112. Epub 2011 Nov 21.


Immunovirological response to combined antiretroviral therapy and drug resistance patterns in children: 1- and 2-year outcomes in rural Uganda.

Ahoua L, Guenther G, Rouzioux C, Pinoges L, Anguzu P, Taburet AM, Balkan S, Olson DM, Olaro C, Pujades-Rodríguez M.

BMC Pediatr. 2011 Jul 26;11:67. doi: 10.1186/1471-2431-11-67.


Tuberculosis treatment in a refugee and migrant population: 20 years of experience on the Thai-Burmese border.

Minetti A, Camelique O, Hsa Thaw K, Thi S, Swaddiwudhipong W, Hewison C, Pinoges L, Bonnet M, Guerin PJ.

Int J Tuberc Lung Dis. 2010 Dec;14(12):1589-95.


Cryptococcal meningitis in HIV-infected patients: a longitudinal study in Cambodia.

Espié E, Pinoges L, Balkan S, Chanchhaya N, Molfino L, Narom P, Pujades-Rodríguez M.

Trop Med Int Health. 2010 Nov;15(11):1375-81. doi: 10.1111/j.1365-3156.2010.02622.x. Epub 2010 Sep 25.


Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda.

Ahoua L, Ayikoru H, Gnauck K, Odaru G, Odar E, Ondoa-Onama C, Pinoges L, Balkan S, Olson D, Pujades-Rodríguez M.

J Trop Pediatr. 2010 Feb;56(1):43-52. doi: 10.1093/tropej/fmp054. Epub 2009 Jul 13.


Risk factors for virological failure and subtherapeutic antiretroviral drug concentrations in HIV-positive adults treated in rural northwestern Uganda.

Ahoua L, Guenther G, Pinoges L, Anguzu P, Chaix ML, Le Tiec C, Balkan S, Olson D, Olaro C, Pujades-Rodríguez M.

BMC Infect Dis. 2009 Jun 3;9:81. doi: 10.1186/1471-2334-9-81.


Immunogenicity of fractional doses of tetravalent a/c/y/w135 meningococcal polysaccharide vaccine: results from a randomized non-inferiority controlled trial in Uganda.

Guerin PJ, Naess LM, Fogg C, Rosenqvist E, Pinoges L, Bajunirwe F, Nabasumba C, Borrow R, Frøholm LO, Ghabri S, Batwala V, Twesigye R, Aaberge IS, Røttingen JA, Piola P, Caugant DA.

PLoS Negl Trop Dis. 2008;2(12):e342. doi: 10.1371/journal.pntd.0000342. Epub 2008 Dec 2.


Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.

Ashley EA, Pinoges L, Turyakira E, Dorsey G, Checchi F, Bukirwa H, van den Broek I, Zongo I, Urruta PP, van Herp M, Balkan S, Taylor WR, Olliaro P, Guthmann JP.

Malar J. 2008 Aug 9;7:154. doi: 10.1186/1475-2875-7-154.


The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria.

Lee SJ, Stepniewska K, Anstey N, Ashley E, Barnes K, Binh TQ, D'Alessandro U, Day NP, de Vries PJ, Dorsey G, Guthmann JP, Mayxay M, Newton P, Nosten F, Olliaro P, Osario L, Pinoges L, Price R, Rowland M, Smithuis F, Taylor R, White NJ.

Malar J. 2008 Aug 2;7:149. doi: 10.1186/1475-2875-7-149.


Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: cohort study.

Priotto G, Pinoges L, Fursa IB, Burke B, Nicolay N, Grillet G, Hewison C, Balasegaram M.

BMJ. 2008 Mar 29;336(7646):705-8. doi: 10.1136/bmj.39485.592674.BE. Epub 2008 Mar 5.


Treatment of severe malnutrition with 2-day intramuscular ceftriaxone vs 5-day amoxicillin.

Dubray C, Ibrahim SA, Abdelmutalib M, Guerin PJ, Dantoine F, Belanger F, Legros D, Pinoges L, Brown V.

Ann Trop Paediatr. 2008 Mar;28(1):13-22. doi: 10.1179/146532808X270635.


Risk associated with asymptomatic parasitaemia occurring post-antimalarial treatment.

Olliaro P, Pinoges L, Checchi F, Vaillant M, Guthmann JP.

Trop Med Int Health. 2008 Jan;13(1):83-90. doi: 10.1111/j.1365-3156.2007.01977.x.


Positive outcomes of HAART at 24 months in HIV-infected patients in Cambodia.

Ferradini L, Laureillard D, Prak N, Ngeth C, Fernandez M, Pinoges L, Puertas G, Taburet AM, Ly N, Rouzioux C, Balkan S, Quillet C, Delfraissy JF.

AIDS. 2007 Nov 12;21(17):2293-301.

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