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Results: 1 to 20 of 122

1.

Intracellular pH modulates quinary structure.

Cohen RD, Guseman AJ, Pielak GJ.

Protein Sci. 2015 Aug 10. doi: 10.1002/pro.2765. [Epub ahead of print]

PMID:
26257390
2.

Emergence of life: Physical chemistry changes the paradigm.

Spitzer J, Pielak GJ, Poolman B.

Biol Direct. 2015 Jun 10;10:33. doi: 10.1186/s13062-015-0060-y.

3.

Quinary structure modulates protein stability in cells.

Monteith WB, Cohen RD, Smith AE, Guzman-Cisneros E, Pielak GJ.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1739-42. doi: 10.1073/pnas.1417415112. Epub 2015 Jan 26.

4.

Hydrogen exchange of disordered proteins in Escherichia coli.

Smith AE, Zhou LZ, Pielak GJ.

Protein Sci. 2015 May;24(5):706-13. doi: 10.1002/pro.2643. Epub 2015 Mar 2.

PMID:
25611326
5.

NMR studies of protein folding and binding in cells and cell-like environments.

Smith AE, Zhang Z, Pielak GJ, Li C.

Curr Opin Struct Biol. 2015 Feb;30:7-16. doi: 10.1016/j.sbi.2014.10.004. Epub 2014 Dec 3. Review.

PMID:
25479354
6.

Residue level quantification of protein stability in living cells.

Monteith WB, Pielak GJ.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11335-40. doi: 10.1073/pnas.1406845111. Epub 2014 Jul 21.

7.

An osmolyte mitigates the destabilizing effect of protein crowding.

Sarkar M, Pielak GJ.

Protein Sci. 2014 Sep;23(9):1161-4. doi: 10.1002/pro.2510. Epub 2014 Jul 15.

8.

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).

Theillet FX, Binolfi A, Frembgen-Kesner T, Hingorani K, Sarkar M, Kyne C, Li C, Crowley PB, Gierasch L, Pielak GJ, Elcock AH, Gershenson A, Selenko P.

Chem Rev. 2014 Jul 9;114(13):6661-714. doi: 10.1021/cr400695p. Epub 2014 Jun 5. Review. No abstract available.

9.

Strategies for protein NMR in Escherichia coli.

Xu G, Ye Y, Liu X, Cao S, Wu Q, Cheng K, Liu M, Pielak GJ, Li C.

Biochemistry. 2014 Apr 1;53(12):1971-81. doi: 10.1021/bi500079u. Epub 2014 Mar 20.

PMID:
24597855
10.

Protein crowder charge and protein stability.

Sarkar M, Lu J, Pielak GJ.

Biochemistry. 2014 Mar 18;53(10):1601-6. doi: 10.1021/bi4016346. Epub 2014 Mar 3.

PMID:
24552162
11.

Impact of reconstituted cytosol on protein stability.

Sarkar M, Smith AE, Pielak GJ.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19342-7. doi: 10.1073/pnas.1312678110. Epub 2013 Nov 11.

12.

The cellular environment stabilizes adenine riboswitch RNA structure.

Tyrrell J, McGinnis JL, Weeks KM, Pielak GJ.

Biochemistry. 2013 Dec 3;52(48):8777-85. doi: 10.1021/bi401207q. Epub 2013 Nov 20.

PMID:
24215455
13.

(19) F NMR spectroscopy as a probe of cytoplasmic viscosity and weak protein interactions in living cells.

Ye Y, Liu X, Zhang Z, Wu Q, Jiang B, Jiang L, Zhang X, Liu M, Pielak GJ, Li C.

Chemistry. 2013 Sep 16;19(38):12705-10. doi: 10.1002/chem.201301657. Epub 2013 Aug 6.

PMID:
23922149
14.

Amide proton exchange of a dynamic loop in cell extracts.

Smith AE, Sarkar M, Young GB, Pielak GJ.

Protein Sci. 2013 Oct;22(10):1313-9. doi: 10.1002/pro.2318. Epub 2013 Aug 20.

15.

Disordered Protein Diffusion under Crowded Conditions.

Wang Y, Benton LA, Singh V, Pielak GJ.

J Phys Chem Lett. 2012 Sep 20;3(18):2703-2706. Epub 2012 Sep 6.

16.

Unexpected effects of macromolecular crowding on protein stability.

Benton LA, Smith AE, Young GB, Pielak GJ.

Biochemistry. 2012 Dec 11;51(49):9773-5. doi: 10.1021/bi300909q. Epub 2012 Nov 27.

PMID:
23167542
17.

Macromolecular crowding and protein stability.

Wang Y, Sarkar M, Smith AE, Krois AS, Pielak GJ.

J Am Chem Soc. 2012 Oct 10;134(40):16614-8. doi: 10.1021/ja305300m. Epub 2012 Sep 27.

PMID:
22954326
18.

Membrane proteins, magic-angle spinning, and in-cell NMR.

Pielak GJ, Tian F.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4715-6. doi: 10.1073/pnas.1201502109. Epub 2012 Mar 12. No abstract available.

19.

Interaction of α-synuclein and a cell penetrating fusion peptide with higher eukaryotic cell membranes assessed by ¹⁹F NMR.

Zigoneanu IG, Pielak GJ.

Mol Pharm. 2012 Apr 2;9(4):1024-9. doi: 10.1021/mp200615m. Epub 2012 Mar 13.

20.

Interaction of α-synuclein with vesicles that mimic mitochondrial membranes.

Zigoneanu IG, Yang YJ, Krois AS, Haque E, Pielak GJ.

Biochim Biophys Acta. 2012 Mar;1818(3):512-9. doi: 10.1016/j.bbamem.2011.11.024. Epub 2011 Dec 3.

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