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Results: 1 to 20 of 120

1.

Quinary structure modulates protein stability in cells.

Monteith WB, Cohen RD, Smith AE, Guzman-Cisneros E, Pielak GJ.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1739-42. doi: 10.1073/pnas.1417415112. Epub 2015 Jan 26.

PMID:
25624496
[PubMed - in process]
2.

Hydrogen exchange of disordered proteins in Escherichia coli.

Smith AE, Zhou Z, Pielak GJ.

Protein Sci. 2015 Jan 21. doi: 10.1002/pro.2643. [Epub ahead of print]

PMID:
25611326
[PubMed - as supplied by publisher]
3.

NMR studies of protein folding and binding in cells and cell-like environments.

Smith AE, Zhang Z, Pielak GJ, Li C.

Curr Opin Struct Biol. 2014 Dec 2;30C:7-16. doi: 10.1016/j.sbi.2014.10.004. [Epub ahead of print] Review.

PMID:
25479354
[PubMed - as supplied by publisher]
4.

Residue level quantification of protein stability in living cells.

Monteith WB, Pielak GJ.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11335-40. doi: 10.1073/pnas.1406845111. Epub 2014 Jul 21.

PMID:
25049396
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

An osmolyte mitigates the destabilizing effect of protein crowding.

Sarkar M, Pielak GJ.

Protein Sci. 2014 Sep;23(9):1161-4. doi: 10.1002/pro.2510. Epub 2014 Jul 15.

PMID:
24963990
[PubMed - in process]
6.

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).

Theillet FX, Binolfi A, Frembgen-Kesner T, Hingorani K, Sarkar M, Kyne C, Li C, Crowley PB, Gierasch L, Pielak GJ, Elcock AH, Gershenson A, Selenko P.

Chem Rev. 2014 Jul 9;114(13):6661-714. doi: 10.1021/cr400695p. Epub 2014 Jun 5. No abstract available.

PMID:
24901537
[PubMed - in process]
Free PMC Article
7.

Strategies for protein NMR in Escherichia coli.

Xu G, Ye Y, Liu X, Cao S, Wu Q, Cheng K, Liu M, Pielak GJ, Li C.

Biochemistry. 2014 Apr 1;53(12):1971-81. doi: 10.1021/bi500079u. Epub 2014 Mar 20.

PMID:
24597855
[PubMed - indexed for MEDLINE]
8.

Protein crowder charge and protein stability.

Sarkar M, Lu J, Pielak GJ.

Biochemistry. 2014 Mar 18;53(10):1601-6. doi: 10.1021/bi4016346. Epub 2014 Mar 3.

PMID:
24552162
[PubMed - indexed for MEDLINE]
9.

Impact of reconstituted cytosol on protein stability.

Sarkar M, Smith AE, Pielak GJ.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19342-7. doi: 10.1073/pnas.1312678110. Epub 2013 Nov 11.

PMID:
24218610
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The cellular environment stabilizes adenine riboswitch RNA structure.

Tyrrell J, McGinnis JL, Weeks KM, Pielak GJ.

Biochemistry. 2013 Dec 3;52(48):8777-85. doi: 10.1021/bi401207q. Epub 2013 Nov 20.

PMID:
24215455
[PubMed - indexed for MEDLINE]
11.

(19) F NMR spectroscopy as a probe of cytoplasmic viscosity and weak protein interactions in living cells.

Ye Y, Liu X, Zhang Z, Wu Q, Jiang B, Jiang L, Zhang X, Liu M, Pielak GJ, Li C.

Chemistry. 2013 Sep 16;19(38):12705-10. doi: 10.1002/chem.201301657. Epub 2013 Aug 6.

PMID:
23922149
[PubMed - indexed for MEDLINE]
12.

Amide proton exchange of a dynamic loop in cell extracts.

Smith AE, Sarkar M, Young GB, Pielak GJ.

Protein Sci. 2013 Oct;22(10):1313-9. doi: 10.1002/pro.2318. Epub 2013 Aug 20.

PMID:
23904228
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Disordered Protein Diffusion under Crowded Conditions.

Wang Y, Benton LA, Singh V, Pielak GJ.

J Phys Chem Lett. 2012 Sep 20;3(18):2703-2706. Epub 2012 Sep 6.

PMID:
23185649
[PubMed]
Free PMC Article
14.

Unexpected effects of macromolecular crowding on protein stability.

Benton LA, Smith AE, Young GB, Pielak GJ.

Biochemistry. 2012 Dec 11;51(49):9773-5. doi: 10.1021/bi300909q. Epub 2012 Nov 27.

PMID:
23167542
[PubMed - indexed for MEDLINE]
15.

Macromolecular crowding and protein stability.

Wang Y, Sarkar M, Smith AE, Krois AS, Pielak GJ.

J Am Chem Soc. 2012 Oct 10;134(40):16614-8. doi: 10.1021/ja305300m. Epub 2012 Sep 27.

PMID:
22954326
[PubMed - indexed for MEDLINE]
16.

Membrane proteins, magic-angle spinning, and in-cell NMR.

Pielak GJ, Tian F.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4715-6. doi: 10.1073/pnas.1201502109. Epub 2012 Mar 12. No abstract available.

PMID:
22411816
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Interaction of α-synuclein and a cell penetrating fusion peptide with higher eukaryotic cell membranes assessed by ¹⁹F NMR.

Zigoneanu IG, Pielak GJ.

Mol Pharm. 2012 Apr 2;9(4):1024-9. doi: 10.1021/mp200615m. Epub 2012 Mar 13.

PMID:
22376087
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Interaction of α-synuclein with vesicles that mimic mitochondrial membranes.

Zigoneanu IG, Yang YJ, Krois AS, Haque E, Pielak GJ.

Biochim Biophys Acta. 2012 Mar;1818(3):512-9. doi: 10.1016/j.bbamem.2011.11.024. Epub 2011 Dec 3.

PMID:
22155643
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

In situ structural characterization of a recombinant protein in native Escherichia coli membranes with solid-state magic-angle-spinning NMR.

Fu R, Wang X, Li C, Santiago-Miranda AN, Pielak GJ, Tian F.

J Am Chem Soc. 2011 Aug 17;133(32):12370-3. doi: 10.1021/ja204062v. Epub 2011 Jul 26.

PMID:
21774553
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

An upper limit for macromolecular crowding effects.

Miklos AC, Li C, Sorrell CD, Lyon LA, Pielak GJ.

BMC Biophys. 2011 May 31;4:13. doi: 10.1186/2046-1682-4-13.

PMID:
21627822
[PubMed]
Free PMC Article
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