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Items: 1 to 20 of 40

1.

Assessment of PARP protein expression in epithelial ovarian cancer by ELISA pharmacodynamic assay and immunohistochemistry.

Veskimäe K, Staff S, Grönholm A, Pesu M, Laaksonen M, Nykter M, Isola J, Mäenpää J.

Tumour Biol. 2016 May 7. [Epub ahead of print]

PMID:
27155850
2.

New insights into the host cell necrosis in tuberculosis.

Pesu M.

Virulence. 2016;7(1):1-2. doi: 10.1080/21505594.2015.1122167. Epub 2015 Nov 25. No abstract available.

PMID:
26605779
3.

The Plasma Level of Proprotein Convertase FURIN in Patients with Suspected Infection in the Emergency Room: A Prospective Cohort Study.

Ranta N, Turpeinen H, Oksanen A, Hämäläinen S, Huttunen R, Uusitalo-Seppälä R, Rintala E, Aittoniemi J, Pesu M.

Scand J Immunol. 2015 Dec;82(6):539-46. doi: 10.1111/sji.12386.

PMID:
26346780
4.

Proprotein convertase FURIN regulates T cell receptor-induced transactivation.

Ortutay Z, Oksanen A, Aittomäki S, Ortutay C, Pesu M.

J Leukoc Biol. 2015 Jul;98(1):73-83. doi: 10.1189/jlb.2A0514-257RR. Epub 2015 Apr 29.

PMID:
25926688
5.

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.

Turpeinen H, Seppälä I, Lyytikäinen LP, Raitoharju E, Hutri-Kähönen N, Levula M, Oksala N, Waldenberger M, Klopp N, Illig T, Mononen N, Laaksonen R, Raitakari O, Kähönen M, Lehtimäki T, Pesu M.

Hum Genet. 2015 Jun;134(6):627-36. doi: 10.1007/s00439-015-1546-5. Epub 2015 Mar 27.

PMID:
25813623
6.

The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.

Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M.

Infect Immun. 2015 Apr;83(4):1431-42. doi: 10.1128/IAI.03135-14. Epub 2015 Jan 26.

7.

Regulation of Inflammatory Cytokine Production by MKP-5 in Macrophages.

Hömmö T, Pesu M, Moilanen E, Korhonen R.

Basic Clin Pharmacol Toxicol. 2015 Aug;117(2):96-104. doi: 10.1111/bcpt.12380. Epub 2015 Feb 25.

PMID:
25615285
8.

Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.

Oksanen A, Aittomäki S, Jankovic D, Ortutay Z, Pulkkinen K, Hämäläinen S, Rokka A, Corthals GL, Watford WT, Junttila I, O'Shea JJ, Pesu M.

J Immunol. 2014 Dec 1;193(11):5470-9. doi: 10.4049/jimmunol.1401629. Epub 2014 Oct 29.

9.

Adequate Th2-type response associates with restricted bacterial growth in latent mycobacterial infection of zebrafish.

Hammarén MM, Oksanen KE, Nisula HM, Luukinen BV, Pesu M, Rämet M, Parikka M.

PLoS Pathog. 2014 Jun 26;10(6):e1004190. doi: 10.1371/journal.ppat.1004190. eCollection 2014 Jun.

10.

Coxsackievirus B1 reveals strain specific differences in plasmacytoid dendritic cell mediated immunogenicity.

Hämäläinen S, Nurminen N, Ahlfors H, Oikarinen S, Sioofy-Khojine AB, Frisk G, Oberste MS, Lahesmaa R, Pesu M, Hyöty H.

J Med Virol. 2014 Aug;86(8):1412-20. doi: 10.1002/jmv.23903. Epub 2014 Feb 20.

PMID:
24616040
11.

Genetics of the first seven proprotein convertase enzymes in health and disease.

Turpeinen H, Ortutay Z, Pesu M.

Curr Genomics. 2013 Nov;14(7):453-67. doi: 10.2174/1389202911314050010.

12.

Zebavidin--an avidin-like protein from zebrafish.

Taskinen B, Zmurko J, Ojanen M, Kukkurainen S, Parthiban M, Määttä JA, Leppiniemi J, Jänis J, Parikka M, Turpeinen H, Rämet M, Pesu M, Johnson MS, Kulomaa MS, Airenne TT, Hytönen VP.

PLoS One. 2013 Oct 24;8(10):e77207. doi: 10.1371/journal.pone.0077207. eCollection 2013.

13.

Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).

Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimäki A, Rämet M, Parikka M, Hytönen VP, Nykter M, Pesu M.

J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31.

14.

Therapeutic targeting of the Jak/STAT pathway.

Aittomäki S, Pesu M.

Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):18-23. doi: 10.1111/bcpt.12164. Epub 2013 Nov 15. Review.

15.

S-layer protein mediates the stimulatory effect of Lactobacillus helveticus MIMLh5 on innate immunity.

Taverniti V, Stuknyte M, Minuzzo M, Arioli S, De Noni I, Scabiosi C, Cordova ZM, Junttila I, Hämäläinen S, Turpeinen H, Mora D, Karp M, Pesu M, Guglielmetti S.

Appl Environ Microbiol. 2013 Feb;79(4):1221-31. doi: 10.1128/AEM.03056-12. Epub 2012 Dec 7.

16.

JAK Kinases in Health and Disease: An Update.

Laurence A, Pesu M, Silvennoinen O, O'Shea J.

Open Rheumatol J. 2012;6:232-44. doi: 10.2174/1874312901206010232. Epub 2012 Sep 7.

17.

Mycobacterium marinum causes a latent infection that can be reactivated by gamma irradiation in adult zebrafish.

Parikka M, Hammarén MM, Harjula SK, Halfpenny NJ, Oksanen KE, Lahtinen MJ, Pajula ET, Iivanainen A, Pesu M, Rämet M.

PLoS Pathog. 2012 Sep;8(9):e1002944. doi: 10.1371/journal.ppat.1002944. Epub 2012 Sep 27.

18.

SAP30L (Sin3A-associated protein 30-like) is involved in regulation of cardiac development and hematopoiesis in zebrafish embryos.

Teittinen KJ, Grönroos T, Parikka M, Junttila S, Uusimäki A, Laiho A, Korkeamäki H, Kurppa K, Turpeinen H, Pesu M, Gyenesei A, Rämet M, Lohi O.

J Cell Biochem. 2012 Dec;113(12):3843-52. doi: 10.1002/jcb.24298.

PMID:
22821512
19.

In vitro functional and immunomodulatory properties of the Lactobacillus helveticus MIMLh5-Streptococcus salivarius ST3 association that are relevant to the development of a pharyngeal probiotic product.

Taverniti V, Minuzzo M, Arioli S, Junttila I, Hämäläinen S, Turpeinen H, Mora D, Karp M, Pesu M, Guglielmetti S.

Appl Environ Microbiol. 2012 Jun;78(12):4209-16. doi: 10.1128/AEM.00325-12. Epub 2012 Apr 13.

20.

Identification of proprotein convertase substrates using genome-wide expression correlation analysis.

Turpeinen H, Kukkurainen S, Pulkkinen K, Kauppila T, Ojala K, Hytönen VP, Pesu M.

BMC Genomics. 2011 Dec 20;12:618. doi: 10.1186/1471-2164-12-618.

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