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Results: 1 to 20 of 129

1.

Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells.

Gallala H, Winter J, Veit N, Nowak M, Perner S, Courts C, Kraus D, Janzen V, Probstmeier R.

Tumour Biol. 2014 Dec 7. [Epub ahead of print]

PMID:
25487614
[PubMed - as supplied by publisher]
2.

Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.

Baumann U, Fernández-Sáiz V, Rudelius M, Lemeer S, Rad R, Knorn AM, Slawska J, Engel K, Jeremias I, Li Z, Tomiatti V, Illert AL, Targosz BS, Braun M, Perner S, Leitges M, Klapper W, Dreyling M, Miething C, Lenz G, Rosenwald A, Peschel C, Keller U, Kuster B, Bassermann F.

Nat Med. 2014 Dec;20(12):1401-9. doi: 10.1038/nm.3740. Epub 2014 Nov 24.

PMID:
25419709
[PubMed - in process]
3.

FGFR1 as a novel prognostic and predictive biomarker in squamous cell cancers of the lung and the head and neck area.

von Mässenhausen A, Franzen A, Heasley L, Perner S.

Ann Transl Med. 2013 Oct;1(3):23. doi: 10.3978/j.issn.2305-5839.2013.06.08.

PMID:
25332967
[PubMed]
Free PMC Article
4.

Analysis of receptor tyrosine kinase gene amplification on the example of FGFR1.

Boehm D, von Mässenhausen A, Perner S.

Methods Mol Biol. 2015;1233:67-79. doi: 10.1007/978-1-4939-1789-1_7.

PMID:
25319890
[PubMed - in process]
5.

Prevention and early detection of prostate cancer.

Cuzick J, Thorat MA, Andriole G, Brawley OW, Brown PH, Culig Z, Eeles RA, Ford LG, Hamdy FC, Holmberg L, Ilic D, Key TJ, La Vecchia C, Lilja H, Marberger M, Meyskens FL, Minasian LM, Parker C, Parnes HL, Perner S, Rittenhouse H, Schalken J, Schmid HP, Schmitz-Dräger BJ, Schröder FH, Stenzl A, Tombal B, Wilt TJ, Wolk A.

Lancet Oncol. 2014 Oct;15(11):e484-92. doi: 10.1016/S1470-2045(14)70211-6. Review.

PMID:
25281467
[PubMed - indexed for MEDLINE]
6.

Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.

Lovly CM, McDonald NT, Chen H, Ortiz-Cuaran S, Heukamp LC, Yan Y, Florin A, Ozretić L, Lim D, Wang L, Chen Z, Chen X, Lu P, Paik PK, Shen R, Jin H, Buettner R, Ansén S, Perner S, Brockmann M, Bos M, Wolf J, Gardizi M, Wright GM, Solomon B, Russell PA, Rogers TM, Suehara Y, Red-Brewer M, Tieu R, de Stanchina E, Wang Q, Zhao Z, Johnson DH, Horn L, Wong KK, Thomas RK, Ladanyi M, Pao W.

Nat Med. 2014 Sep;20(9):1027-34. doi: 10.1038/nm.3667. Epub 2014 Aug 31.

PMID:
25173427
[PubMed - indexed for MEDLINE]
7.

Prognostic significance of YWHAZ expression in localized prostate cancer.

Rüenauver K, Menon R, Svensson MA, Carlsson J, Vogel W, Andrén O, Nowak M, Perner S.

Prostate Cancer Prostatic Dis. 2014 Dec;17(4):310-4. doi: 10.1038/pcan.2014.32. Epub 2014 Aug 26.

PMID:
25156059
[PubMed - in process]
8.

Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis.

Heselmeyer-Haddad KM, Berroa Garcia LY, Bradley A, Hernandez L, Hu Y, Habermann JK, Dumke C, Thorns C, Perner S, Pestova E, Burke C, Chowdhury SA, Schwartz R, Schäffer AA, Paris PL, Ried T.

Am J Pathol. 2014 Oct;184(10):2671-86. doi: 10.1016/j.ajpath.2014.06.030. Epub 2014 Aug 14.

PMID:
25131421
[PubMed - in process]
Free Article
9.

KDM5C is overexpressed in prostate cancer and is a prognostic marker for prostate-specific antigen-relapse following radical prostatectomy.

Stein J, Majores M, Rohde M, Lim S, Schneider S, Krappe E, Ellinger J, Dietel M, Stephan C, Jung K, Perner S, Kristiansen G, Kirfel J.

Am J Pathol. 2014 Sep;184(9):2430-7. doi: 10.1016/j.ajpath.2014.05.022. Epub 2014 Jul 9.

PMID:
25016185
[PubMed - in process]
10.

Nonamplified FGFR1 is a growth driver in malignant pleural mesothelioma.

Marek LA, Hinz TK, von Mässenhausen A, Olszewski KA, Kleczko EK, Boehm D, Weiser-Evans MC, Nemenoff RA, Hoffmann H, Warth A, Gozgit JM, Perner S, Heasley LE.

Mol Cancer Res. 2014 Oct;12(10):1460-9. doi: 10.1158/1541-7786.MCR-14-0038. Epub 2014 Jun 25.

PMID:
24966347
[PubMed - in process]
11.

MED12 overexpression is a frequent event in castration-resistant prostate cancer.

Shaikhibrahim Z, Offermann A, Braun M, Menon R, Syring I, Nowak M, Halbach R, Vogel W, Ruiz C, Zellweger T, Rentsch CA, Svensson M, Andren O, Bubendorf L, Biskup S, Duensing S, Kirfel J, Perner S.

Endocr Relat Cancer. 2014 Aug;21(4):663-75. doi: 10.1530/ERC-14-0171. Epub 2014 Jun 17.

PMID:
24938407
[PubMed - in process]
12.

Comparison of different prostatic markers in lymph node and distant metastases of prostate cancer.

Queisser A, Hagedorn SA, Braun M, Vogel W, Duensing S, Perner S.

Mod Pathol. 2015 Jan;28(1):138-45. doi: 10.1038/modpathol.2014.77. Epub 2014 Jun 13.

PMID:
24925052
[PubMed - in process]
13.

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.

Wynes MW, Hinz TK, Gao D, Martini M, Marek LA, Ware KE, Edwards MG, Böhm D, Perner S, Helfrich BA, Dziadziuszko R, Jassem J, Wojtylak S, Sejda A, Gozgit JM, Bunn PA Jr, Camidge DR, Tan AC, Hirsch FR, Heasley LE.

Clin Cancer Res. 2014 Jun 15;20(12):3299-309. doi: 10.1158/1078-0432.CCR-13-3060. Epub 2014 Apr 25.

PMID:
24771645
[PubMed - in process]
14.

Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma.

Schröck A, Bode M, Göke FJ, Bareiss PM, Schairer R, Wang H, Weichert W, Franzen A, Kirsten R, van Bremen T, Queisser A, Kristiansen G, Heasley L, Bootz F, Lengerke C, Perner S.

Carcinogenesis. 2014 Jul;35(7):1636-42. doi: 10.1093/carcin/bgu094. Epub 2014 Apr 17.

PMID:
24743512
[PubMed - indexed for MEDLINE]
15.

In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.

Menzel M, Meckbach D, Weide B, Toussaint NC, Schilbach K, Noor S, Eigentler T, Ikenberg K, Busch C, Quintanilla-Martinez L, Kohlhofer U, Göke A, Göke F, Handgretinger R, Ottmann C, Bastian BC, Garbe C, Röcken M, Perner S, Kohlbacher O, Bauer J.

Pigment Cell Melanoma Res. 2014 Jul;27(4):671-3. doi: 10.1111/pcmr.12249. Epub 2014 May 6. No abstract available.

PMID:
24703331
[PubMed - in process]
16.

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids.

Fernandez-Cuesta L, Peifer M, Lu X, Sun R, Ozretić L, Seidel D, Zander T, Leenders F, George J, Müller C, Dahmen I, Pinther B, Bosco G, Konrad K, Altmüller J, Nürnberg P, Achter V, Lang U, Schneider PM, Bogus M, Soltermann A, Brustugun OT, Helland Å, Solberg S, Lund-Iversen M, Ansén S, Stoelben E, Wright GM, Russell P, Wainer Z, Solomon B, Field JK, Hyde R, Davies MP, Heukamp LC, Petersen I, Perner S, Lovly CM, Cappuzzo F, Travis WD, Wolf J, Vingron M, Brambilla E, Haas SA, Buettner R, Thomas RK.

Nat Commun. 2014 Mar 27;5:3518. doi: 10.1038/ncomms4518.

PMID:
24670920
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, McCallie D Jr, Szolovits P, Willard HF, Mendelsohn NJ, Temme R, Finkel RS, Yum SW, Medne L, Sunyaev SR, Adzhubey I, Cassa CA, de Bakker PI, Duzkale H, Dworzyński P, Fairbrother W, Francioli L, Funke BH, Giovanni MA, Handsaker RE, Lage K, Lebo MS, Lek M, Leshchiner I, MacArthur DG, McLaughlin HM, Murray MF, Pers TH, Polak PP, Raychaudhuri S, Rehm HL, Soemedi R, Stitziel NO, Vestecka S, Supper J, Gugenmus C, Klocke B, Hahn A, Schubach M, Menzel M, Biskup S, Freisinger P, Deng M, Braun M, Perner S, Smith RJ, Andorf JL, Huang J, Ryckman K, Sheffield VC, Stone EM, Bair T, Black-Ziegelbein EA, Braun TA, Darbro B, DeLuca AP, Kolbe DL, Scheetz TE, Shearer AE, Sompallae R, Wang K, Bassuk AG, Edens E, Mathews K, Moore SA, Shchelochkov OA, Trapane P, Bossler A, Campbell CA, Heusel JW, Kwitek A, Maga T, Panzer K, Wassink T, Van Daele D, Azaiez H, Booth K, Meyer N, Segal MM, Williams MS, Tromp G, White P, Corsmeier D, Fitzgerald-Butt S, Herman G, Lamb-Thrush D, McBride KL, Newsom D, Pierson CR, Rakowsky AT, Maver A, Lovrečić L, Palandačić A, Peterlin B, Torkamani A, Wedell A, Huss M, Alexeyenko A, Lindvall JM, Magnusson M, Nilsson D, Stranneheim H, Taylan F, Gilissen C, Hoischen A, van Bon B, Yntema H, Nelen M, Zhang W, Sager J, Zhang L, Blair K, Kural D, Cariaso M, Lennon GG, Javed A, Agrawal S, Ng PC, Sandhu KS, Krishna S, Veeramachaneni V, Isakov O, Halperin E, Friedman E, Shomron N, Glusman G, Roach JC, Caballero J, Cox HC, Mauldin D, Ament SA, Rowen L, Richards DR, San Lucas FA, Gonzalez-Garay ML, Caskey CT, Bai Y, Huang Y, Fang F, Zhang Y, Wang Z, Barrera J, Garcia-Lobo JM, González-Lamuño D, Llorca J, Rodriguez MC, Varela I, Reese MG, De La Vega FM, Kiruluta E, Cargill M, Hart RK, Sorenson JM, Lyon GJ, Stevenson DA, Bray BE, Moore BM, Eilbeck K, Yandell M, Zhao H, Hou L, Chen X, Yan X, Chen M, Li C, Yang C, Gunel M, Li P, Kong Y, Alexander AC, Albertyn ZI, Boycott KM, Bulman DE, Gordon PM, Innes AM, Knoppers BM, Majewski J, Marshall CR, Parboosingh JS, Sawyer SL, Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM.

Genome Biol. 2014 Mar 25;15(3):R53. doi: 10.1186/gb-2014-15-3-r53.

PMID:
24667040
[PubMed - in process]
Free PMC Article
18.

Expression profiles for 14-3-3 zeta and CCL20 in pancreatic cancer and chronic pancreatitis.

Klemm C, Dommisch H, Göke F, Kreppel M, Jepsen S, Rolf F, Dommisch K, Perner S, Standop J.

Pathol Res Pract. 2014 Jun;210(6):335-41. doi: 10.1016/j.prp.2014.01.001. Epub 2014 Feb 17.

PMID:
24629487
[PubMed - indexed for MEDLINE]
19.

Staurosporine and extracellular matrix proteins mediate the conversion of small cell lung carcinoma cells into a neuron-like phenotype.

Murmann T, Carrillo-García C, Veit N, Courts C, Glassmann A, Janzen V, Madea B, Reinartz M, Harzen A, Nowak M, Perner S, Winter J, Probstmeier R.

PLoS One. 2014 Feb 28;9(2):e86910. doi: 10.1371/journal.pone.0086910. eCollection 2014.

PMID:
24586258
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A new bright-field dual-colour chromogenic and silver in situ hybridization method for the detection of FGFR1 gene copy number status.

Boehm D, Vogel W, Franzen A, Schrock A, Bootz F, Heaseley LE, Braun M, Perner S.

Virchows Arch. 2014 May;464(5):547-51. doi: 10.1007/s00428-014-1564-z. Epub 2014 Mar 2.

PMID:
24584974
[PubMed - indexed for MEDLINE]

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