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Items: 1 to 20 of 366

1.

Life-saving Antimicrobial Drugs: What Are We Doing to Pricing and Availability?

Perfect JR.

Clin Infect Dis. 2016 Mar 23. pii: ciw153. [Epub ahead of print] No abstract available.

PMID:
27009252
2.

Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis.

Marty FM, Ostrosky-Zeichner L, Cornely OA, Mullane KM, Perfect JR, Thompson GR 3rd, Alangaden GJ, Brown JM, Fredricks DN, Heinz WJ, Herbrecht R, Klimko N, Klyasova G, Maertens JA, Melinkeri SR, Oren I, Pappas PG, Ráčil Z, Rahav G, Santos R, Schwartz S, Vehreschild JJ, Young JH, Chetchotisakd P, Jaruratanasirikul S, Kanj SS, Engelhardt M, Kaufhold A, Ito M, Lee M, Sasse C, Maher RM, Zeiher B, Vehreschild MJ; VITAL and FungiScope Mucormycosis Investigators.

Lancet Infect Dis. 2016 Mar 8. pii: S1473-3099(16)00071-2. doi: 10.1016/S1473-3099(16)00071-2. [Epub ahead of print]

PMID:
26969258
3.

Cryptococcosis.

Maziarz EK, Perfect JR.

Infect Dis Clin North Am. 2016 Mar;30(1):179-206. doi: 10.1016/j.idc.2015.10.006. Review.

PMID:
26897067
4.

"Is there an emerging need for new antifungals?"

Perfect JR.

Expert Opin Emerg Drugs. 2016 Mar 7:1-3. [Epub ahead of print] No abstract available.

PMID:
26883732
5.

CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.

Swamydas M, Gao JL, Break TJ, Johnson MD, Jaeger M, Rodriguez CA, Lim JK, Green NM, Collar AL, Fischer BG, Lee CC, Perfect JR, Alexander BD, Kullberg BJ, Netea MG, Murphy PM, Lionakis MS.

Sci Transl Med. 2016 Jan 20;8(322):322ra10. doi: 10.1126/scitranslmed.aac7718.

PMID:
26791948
6.

Correction to Molecular Umbrella-Amphotericin B Conjugates.

Janout V, Bienvenu C, Schell W, Perfect JR, Regen SL.

Bioconjug Chem. 2015 Oct 21;26(10):2168. doi: 10.1021/acs.bioconjchem.5b00517. Epub 2015 Sep 30. No abstract available.

7.

Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion.

Tenor JL, Oehlers SH, Yang JL, Tobin DM, Perfect JR.

MBio. 2015 Sep 29;6(5):e01425-15. doi: 10.1128/mBio.01425-15.

8.

Taming Amphotericin B.

Janout V, Schell WA, Thévenin D, Yu Y, Perfect JR, Regen SL.

Bioconjug Chem. 2015 Oct 21;26(10):2021-4. doi: 10.1021/acs.bioconjchem.5b00463. Epub 2015 Sep 10.

PMID:
26340430
9.

Scedosporium apiosermum infection of the "Native" valve: Fungal endocarditis in an orthotopic heart transplant recipient.

Clement ME, Maziarz EK, Schroder JN, Patel CB, Perfect JR.

Med Mycol Case Rep. 2015 Jul 30;9:34-6. doi: 10.1016/j.mmcr.2015.07.005. eCollection 2015 Sep.

10.

AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: study protocol for a randomized controlled trial.

Molefi M, Chofle AA, Molloy SF, Kalluvya S, Changalucha JM, Cainelli F, Leeme T, Lekwape N, Goldberg DW, Haverkamp M, Bisson GP, Perfect JR, Letang E, Fenner L, Meintjes G, Burton R, Makadzange T, Ndhlovu CE, Hope W, Harrison TS, Jarvis JN.

Trials. 2015 Jun 17;16:276. doi: 10.1186/s13063-015-0799-6.

11.

Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana.

Chen Y, Litvintseva AP, Frazzitta AE, Haverkamp MR, Wang L, Fang C, Muthoga C, Mitchell TG, Perfect JR.

Mol Ecol. 2015 Jul;24(14):3559-71. doi: 10.1111/mec.13260. Epub 2015 Jul 7.

12.

Next generation multilocus sequence typing (NGMLST) and the analytical software program MLSTEZ enable efficient, cost-effective, high-throughput, multilocus sequencing typing.

Chen Y, Frazzitta AE, Litvintseva AP, Fang C, Mitchell TG, Springer DJ, Ding Y, Yuan G, Perfect JR.

Fungal Genet Biol. 2015 Feb;75:64-71. doi: 10.1016/j.fgb.2015.01.005. Epub 2015 Jan 24.

13.

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.

Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LA, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG.

Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-74. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13.

PMID:
25579795
14.

Update on epidemiology of and preventive strategies for invasive fungal infections in cancer patients.

Perfect JR, Hachem R, Wingard JR.

Clin Infect Dis. 2014 Nov 15;59 Suppl 5:S352-5. doi: 10.1093/cid/ciu639. Review.

15.

Cryptococcosis diagnosis and treatment: What do we know now.

Perfect JR, Bicanic T.

Fungal Genet Biol. 2015 May;78:49-54. doi: 10.1016/j.fgb.2014.10.003. Epub 2014 Oct 13. Review.

16.

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.

Kumar V, Cheng SC, Johnson MD, Smeekens SP, Wojtowicz A, Giamarellos-Bourboulis E, Karjalainen J, Franke L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JW, Joosten LA, Sokol H, Bauer H, Herrmann BG, Bochud PY, Marchetti O, Perfect JR, Xavier RJ, Kullberg BJ, Wijmenga C, Netea MG.

Nat Commun. 2014 Sep 8;5:4675. doi: 10.1038/ncomms5675.

PMID:
25197941
17.

Molecular umbrella-amphotericin B conjugates.

Janout V, Bienvenu C, Schell W, Perfect JR, Regen SL.

Bioconjug Chem. 2014 Aug 20;25(8):1408-11. doi: 10.1021/bc500277v. Epub 2014 Aug 1. Erratum in: Bioconjug Chem. 2015 Oct 21;26(10):2168.

18.

Mucormycosis Rhinosinusitis at Diagnosis of Acute Lymphoblastic Leukemia: Diagnostics and Management Challenges in a Low-Middle-income Country.

Mandegari E, Fu L, Arambú C, Montoya S, Peña A, Johnson KM, Perfect JR, Caniza MA.

J Pediatr Hematol Oncol. 2015 Apr;37(3):e173-7. doi: 10.1097/MPH.0000000000000198.

PMID:
24942033
19.

Very low levels of 25-hydroxyvitamin D are not associated with immunologic changes or clinical outcome in South African patients with HIV-associated cryptococcal meningitis.

Jarvis JN, Bicanic T, Loyse A, Meintjes G, Hogan L, Roberts CH, Shoham S, Perfect JR, Govender NP, Harrison TS.

Clin Infect Dis. 2014 Aug 15;59(4):493-500. doi: 10.1093/cid/ciu349. Epub 2014 May 13.

20.

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.

Janbon G, Ormerod KL, Paulet D, Byrnes EJ 3rd, Yadav V, Chatterjee G, Mullapudi N, Hon CC, Billmyre RB, Brunel F, Bahn YS, Chen W, Chen Y, Chow EW, Coppée JY, Floyd-Averette A, Gaillardin C, Gerik KJ, Goldberg J, Gonzalez-Hilarion S, Gujja S, Hamlin JL, Hsueh YP, Ianiri G, Jones S, Kodira CD, Kozubowski L, Lam W, Marra M, Mesner LD, Mieczkowski PA, Moyrand F, Nielsen K, Proux C, Rossignol T, Schein JE, Sun S, Wollschlaeger C, Wood IA, Zeng Q, Neuvéglise C, Newlon CS, Perfect JR, Lodge JK, Idnurm A, Stajich JE, Kronstad JW, Sanyal K, Heitman J, Fraser JA, Cuomo CA, Dietrich FS.

PLoS Genet. 2014 Apr 17;10(4):e1004261. doi: 10.1371/journal.pgen.1004261. eCollection 2014 Apr.

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