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Items: 1 to 20 of 89


Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis.

Marquès JM, Belza I, Holtmann B, Pennica D, Prieto J, Bustos M.

Hepatology. 2007 Mar;45(3):639-48.


Cardiotrophin-1 defends the liver against ischemia-reperfusion injury and mediates the protective effect of ischemic preconditioning.

Iñiguez M, Berasain C, Martinez-Ansó E, Bustos M, Fortes P, Pennica D, Avila MA, Prieto J.

J Exp Med. 2006 Dec 25;203(13):2809-15. Epub 2006 Dec 18.


The lack of cardiotrophin-1 alters expression of interleukin-6 and leukemia inhibitory factor mRNA but does not impair cardiac injury response.

Gritman K, Van Winkle DM, Lorentz CU, Pennica D, Habecker BA.

Cytokine. 2006 Oct;36(1-2):9-16. Epub 2006 Dec 5.


Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function.

Holtmann B, Wiese S, Samsam M, Grohmann K, Pennica D, Martini R, Sendtner M.

J Neurosci. 2005 Feb 16;25(7):1778-87.


BMP signaling initiates a neural crest differentiation program in embryonic rat CNS stem cells.

Gajavelli S, Wood PM, Pennica D, Whittemore SR, Tsoulfas P.

Exp Neurol. 2004 Aug;188(2):205-23.


Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system.

Gard AL, Gavin E, Solodushko V, Pennica D.

Neuroscience. 2004;127(1):43-52.


Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes.

Railson JE, Liao Z, Brar BK, Buddle JC, Pennica D, Stephanou A, Latchman DS.

Cytokine. 2002 Mar 7;17(5):243-53.


Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion.

Liao Z, Brar BK, Cai Q, Stephanou A, O'Leary RM, Pennica D, Yellon DM, Latchman DS.

Cardiovasc Res. 2002 Mar;53(4):902-10.


Increased expression of cardiotrophin-1 during ventricular remodeling in hypertensive rats.

Takimoto Y, Aoyama T, Iwanaga Y, Izumi T, Kihara Y, Pennica D, Sasayama S.

Am J Physiol Heart Circ Physiol. 2002 Mar;282(3):H896-901.


Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling.

Tice DA, Szeto W, Soloviev I, Rubinfeld B, Fong SE, Dugger DL, Winer J, Williams PM, Wieand D, Smith V, Schwall RH, Pennica D, Polakis P.

J Biol Chem. 2002 Apr 19;277(16):14329-35. Epub 2002 Feb 6.


CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1/2 pathways.

Brar BK, Stephanou A, Pennica D, Latchman DS.

Cytokine. 2001 Nov 7;16(3):93-6.


WISP-1 binds to decorin and biglycan.

Desnoyers L, Arnott D, Pennica D.

J Biol Chem. 2001 Dec 14;276(50):47599-607. Epub 2001 Oct 11.


Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation.

Brar BK, Stephanou A, Liao Z, O'Leary RM, Pennica D, Yellon DM, Latchman DS.

Cardiovasc Res. 2001 Aug 1;51(2):265-74.


Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1.

Tao W, Pennica D, Xu L, Kalejta RF, Levine AJ.

Genes Dev. 2001 Jul 15;15(14):1796-807.


Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect.

Railson JE, Lawrence K, Buddle JC, Pennica D, Latchman DS.

J Mol Cell Cardiol. 2001 Jun;33(6):1209-21.


Effects of cardiotrophin-1 (CT-1) in a mouse motor neuron disease.

Mitsumoto H, Klinkosz B, Pioro EP, Tsuzaka K, Ishiyama T, O'Leary RM, Pennica D.

Muscle Nerve. 2001 Jun;24(6):769-77.


Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid.

Szeto W, Jiang W, Tice DA, Rubinfeld B, Hollingshead PG, Fong SE, Dugger DL, Pham T, Yansura DG, Wong TA, Grimaldi JC, Corpuz RT, Singh JS, Frantz GD, Devaux B, Crowley CW, Schwall RH, Eberhard DA, Rastelli L, Polakis P, Pennica D.

Cancer Res. 2001 May 15;61(10):4197-205.


Report and abstracts on the first international workshop on the CCN family of genes.

Ayer-Lelievre C, Brigstock D, Lau L, Pennica D, Perbal B, Yeger H.

Mol Pathol. 2001 Apr;54(2):105-20. No abstract available.


Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons.

Oppenheim RW, Wiese S, Prevette D, Armanini M, Wang S, Houenou LJ, Holtmann B, Gotz R, Pennica D, Sendtner M.

J Neurosci. 2001 Feb 15;21(4):1283-91.

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