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Results: 1 to 20 of 49

1.

Epistasis and the sensitivity of phenotypic screens for beta thalassaemia.

Penman BS, Gupta S, Weatherall DJ.

Br J Haematol. 2015 Apr;169(1):117-28. doi: 10.1111/bjh.13241. Epub 2014 Dec 17.

PMID:
25521998
2.

Pathogen selection drives nonoverlapping associations between HLA loci.

Penman BS, Ashby B, Buckee CO, Gupta S.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19645-50. doi: 10.1073/pnas.1304218110. Epub 2013 Nov 13.

3.

The emergence and maintenance of sickle cell hotspots in the Mediterranean.

Penman BS, Gupta S, Buckee CO.

Infect Genet Evol. 2012 Oct;12(7):1543-50. doi: 10.1016/j.meegid.2012.06.001. Epub 2012 Jun 13.

4.

Negative epistasis between α+ thalassaemia and sickle cell trait can explain interpopulation variation in South Asia.

Penman BS, Habib S, Kanchan K, Gupta S.

Evolution. 2011 Dec;65(12):3625-32. doi: 10.1111/j.1558-5646.2011.01408.x. Epub 2011 Aug 11.

5.

Genome-wide association studies in Plasmodium species.

Penman B, Buckee C, Gupta S, Nee S.

BMC Biol. 2010 Jul 13;8:90. doi: 10.1186/1741-7007-8-90.

6.

Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean.

Penman BS, Pybus OG, Weatherall DJ, Gupta S.

Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21242-6. doi: 10.1073/pnas.0910840106. Epub 2009 Dec 1.

7.

Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis.

Buckee CO, Jolley KA, Recker M, Penman B, Kriz P, Gupta S, Maiden MC.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15082-7. doi: 10.1073/pnas.0712019105. Epub 2008 Sep 24.

8.

Evolution of virulence in malaria.

Penman B, Gupta S.

J Biol. 2008 Aug 28;7(6):22. doi: 10.1186/jbiol83. Review.

9.

Negative epistasis between the malaria-protective effects of alpha+-thalassemia and the sickle cell trait.

Williams TN, Mwangi TW, Wambua S, Peto TE, Weatherall DJ, Gupta S, Recker M, Penman BS, Uyoga S, Macharia A, Mwacharo JK, Snow RW, Marsh K.

Nat Genet. 2005 Nov;37(11):1253-7. Epub 2005 Oct 16.

10.

Human-cell mutagens in respirable airborne particles in the northeastern United States. 1. Mutagenicity of fractionated samples.

Pedersen DU, Durant JL, Penman BW, Crespi CL, Hemond HF, Lafleur AL, Cass GR.

Environ Sci Technol. 2004 Feb 1;38(3):682-9.

PMID:
14968851
11.

Human cell mutagenicity of chlorinated and unchlorinated water and the disinfection byproduct 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).

Woodruff NW, Durant JL, Donhoffner LL, Penman BW, Crespi CL.

Mutat Res. 2001 Aug 22;495(1-2):157-68.

PMID:
11448653
12.

Mutagenicity of C24H14 PAH in human cells expressing CYP1A1.

Durant JL, Lafleur AL, Busby WF Jr, Donhoffner LL, Penman BW, Crespi CL.

Mutat Res. 1999 Oct 29;446(1):1-14.

PMID:
10613181
13.

Transport and metabolic characterization of Caco-2 cells expressing CYP3A4 and CYP3A4 plus oxidoreductase.

Hu M, Li Y, Davitt CM, Huang SM, Thummel K, Penman BW, Crespi CL.

Pharm Res. 1999 Sep;16(9):1352-9.

PMID:
10496649
14.

Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.

Code EL, Crespi CL, Penman BW, Gonzalez FJ, Chang TK, Waxman DJ.

Drug Metab Dispos. 1997 Aug;25(8):985-93.

15.

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450.

Crespi CL, Miller VP, Penman BW.

Anal Biochem. 1997 May 15;248(1):188-90. No abstract available.

PMID:
9177742
16.

Coexpression of cytochrome P4502A6 and human NADPH-P450 oxidoreductase in the baculovirus system.

Chen L, Buters JT, Hardwick JP, Tamura S, Penman BW, Gonzalez FJ, Crespi CL.

Drug Metab Dispos. 1997 Apr;25(4):399-405.

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Human cell mutagenicity of oxygenated, nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols.

Durant JL, Busby WF Jr, Lafleur AL, Penman BW, Crespi CL.

Mutat Res. 1996 Dec 20;371(3-4):123-57.

PMID:
9008716
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