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Items: 1 to 20 of 795

1.

The effect of surfactants on the dissolution behavior of amorphous formulations.

Mah PT, Peltonen L, Novakovic D, Rades T, Strachan CJ, Laaksonen T.

Eur J Pharm Biopharm. 2016 Mar 5. pii: S0939-6411(16)30083-2. doi: 10.1016/j.ejpb.2016.03.007. [Epub ahead of print]

PMID:
26955750
2.

Comparison of automatic summarisation methods for clinical free text notes.

Moen H, Peltonen LM, Heimonen J, Airola A, Pahikkala T, Salakoski T, Salanterä S.

Artif Intell Med. 2016 Feb;67:25-37. doi: 10.1016/j.artmed.2016.01.003. Epub 2016 Jan 21.

3.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
4.

Understanding Critical Quality Attributes for Nanocrystals from Preparation to Delivery.

Peltonen L, Strachan C.

Molecules. 2015 Dec 12;20(12):22286-300. doi: 10.3390/molecules201219851. Review.

5.

An Integrative Literature Review of Organisational Factors Associated with Admission and Discharge Delays in Critical Care.

Peltonen LM, McCallum L, Siirala E, Haataja M, Lundgrén-Laine H, Salanterä S, Lin F.

Biomed Res Int. 2015;2015:868653. doi: 10.1155/2015/868653. Epub 2015 Oct 19. Review.

6.

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, Rayner NW, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT, Lobbens S, Luan J, Lyssenko V, Männistö S, McLeod O, Meyer J, Mihailov E, Mirza G, Mühleisen TW, Müller-Nurasyid M, Navarro C, Nöthen MM, Oskolkov NN, Owen KR, Palli D, Pechlivanis S, Peltonen L, Perry JR, Platou CG, Roden M, Ruderfer D, Rybin D, van der Schouw YT, Sennblad B, Sigurðsson G, Stančáková A, Steinbach G, Storm P, Strauch K, Stringham HM, Sun Q, Thorand B, Tikkanen E, Tonjes A, Trakalo J, Tremoli E, Tuomi T, Wennauer R, Wiltshire S, Wood AR, Zeggini E, Dunham I, Birney E, Pasquali L, Ferrer J, Loos RJ, Dupuis J, Florez JC, Boerwinkle E, Pankow JS, van Duijn C, Sijbrands E, Meigs JB, Hu FB, Thorsteinsdottir U, Stefansson K, Lakka TA, Rauramaa R, Stumvoll M, Pedersen NL, Lind L, Keinanen-Kiukaanniemi SM, Korpi-Hyövälti E, Saaristo TE, Saltevo J, Kuusisto J, Laakso M, Metspalu A, Erbel R, Jöcke KH, Moebus S, Ripatti S, Salomaa V, Ingelsson E, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Koistinen H, Tuomilehto J, Hveem K, Njølstad I, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, de Faire U, Hamsten A, Illig T, Peters A, Cauchi S, Sladek R, Froguel P, Hansen T, Pedersen O, Morris AD, Palmer CN, Kathiresan S, Melander O, Nilsson PM, Groop LC, Barroso I, Langenberg C, Wareham NJ, O'Callaghan CA, Gloyn AL, Altshuler D, Boehnke M, Teslovich TM, McCarthy MI, Morris AP; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium.

Nat Genet. 2015 Dec;47(12):1415-25. doi: 10.1038/ng.3437. Epub 2015 Nov 9.

PMID:
26551672
7.

Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions.

Darville N, Saarinen J, Isomäki A, Khriachtchev L, Cleeren D, Sterkens P, van Heerden M, Annaert P, Peltonen L, Santos HA, Strachan CJ, Van den Mooter G.

Eur J Pharm Biopharm. 2015 Oct;96:338-48. doi: 10.1016/j.ejpb.2015.09.003. Epub 2015 Sep 5.

PMID:
26347923
8.

Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide.

Mah PT, Laaksonen T, Rades T, Peltonen L, Strachan CJ.

Eur J Pharm Sci. 2015 Dec 1;80:74-81. doi: 10.1016/j.ejps.2015.08.006. Epub 2015 Aug 19.

PMID:
26296864
9.

A Pooled Genome-Wide Association Study of Asperger Syndrome.

Warrier V, Chakrabarti B, Murphy L, Chan A, Craig I, Mallya U, Lakatošová S, Rehnstrom K, Peltonen L, Wheelwright S, Allison C, Fisher SE, Baron-Cohen S.

PLoS One. 2015 Jul 15;10(7):e0131202. doi: 10.1371/journal.pone.0131202. eCollection 2015.

10.

Care episode retrieval: distributional semantic models for information retrieval in the clinical domain.

Moen H, Ginter F, Marsi E, Peltonen LM, Salakoski T, Salanterä S.

BMC Med Inform Decis Mak. 2015;15 Suppl 2:S2. doi: 10.1186/1472-6947-15-S2-S2. Epub 2015 Jun 15.

11.

Polymer incorporation method affects the physical stability of amorphous indomethacin in aqueous suspension.

Surwase SA, Itkonen L, Aaltonen J, Saville D, Rades T, Peltonen L, Strachan CJ.

Eur J Pharm Biopharm. 2015 Oct;96:32-43. doi: 10.1016/j.ejpb.2015.06.005. Epub 2015 Jun 16.

PMID:
26092472
12.

Central trends in nursing informatics: students' reflections from International Congress on Nursing Informatics 2014 (Taipei, Taiwan).

Topaz M, Ronquillo C, Pruinelli L, Ramos R, Peltonen LM, Siirala E, Atique S, Hamann G, Badger MK.

Comput Inform Nurs. 2015 Mar;33(3):85-9. doi: 10.1097/CIN.0000000000000139. No abstract available.

PMID:
25793554
13.

Solid formulations by a nanocrystal approach: critical process parameters regarding scale-ability of nanocrystals for tableting applications.

Tuomela A, Laaksonen T, Laru J, Antikainen O, Kiesvaara J, Ilkka J, Oksala O, Rönkkö S, Järvinen K, Hirvonen J, Peltonen L.

Int J Pharm. 2015 May 15;485(1-2):77-86. doi: 10.1016/j.ijpharm.2015.03.009. Epub 2015 Mar 5.

PMID:
25746735
14.

Neuronal ceroid lipofuscinosis genes, CLN2, CLN3 and CLN5 are spatially and temporally co-expressed in a developing mouse brain.

Fabritius AL, Vesa J, Minye HM, Nakano I, Kornblum H, Peltonen L.

Exp Mol Pathol. 2014 Dec;97(3):484-91. doi: 10.1016/j.yexmp.2014.10.003. Epub 2014 Oct 7.

PMID:
25303899
15.

Interaction studies between indomethacin nanocrystals and PEO/PPO copolymer stabilizers.

Liu P, Viitala T, Kartal-Hodzic A, Liang H, Laaksonen T, Hirvonen J, Peltonen L.

Pharm Res. 2015 Feb;32(2):628-39. doi: 10.1007/s11095-014-1491-3. Epub 2014 Aug 22.

PMID:
25145336
16.

The correlation between reading and mathematics ability at age twelve has a substantial genetic component.

Davis OS, Band G, Pirinen M, Haworth CM, Meaburn EL, Kovas Y, Harlaar N, Docherty SJ, Hanscombe KB, Trzaskowski M, Curtis CJ, Strange A, Freeman C, Bellenguez C, Su Z, Pearson R, Vukcevic D, Langford C, Deloukas P, Hunt S, Gray E, Dronov S, Potter SC, Tashakkori-Ghanbaria A, Edkins S, Bumpstead SJ, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin A, Duncanson A, Jankowski JA, Markus HS, Mathew CG, Palmer CN, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood NW, Barroso I, Peltonen L, Dale PS, Petrill SA, Schalkwyk LS, Craig IW, Lewis CM, Price TS; Wellcome Trust Case Control Consortium 2, Donnelly P, Plomin R, Spencer CC.

Nat Commun. 2014 Jul 8;5:4204. doi: 10.1038/ncomms5204.

17.

A genome wide association study of mathematical ability reveals an association at chromosome 3q29, a locus associated with autism and learning difficulties: a preliminary study.

Baron-Cohen S, Murphy L, Chakrabarti B, Craig I, Mallya U, Lakatošová S, Rehnstrom K, Peltonen L, Wheelwright S, Allison C, Fisher SE, Warrier V.

PLoS One. 2014 May 6;9(5):e96374. doi: 10.1371/journal.pone.0096374. eCollection 2014.

18.

Brinzolamide nanocrystal formulations for ophthalmic delivery: reduction of elevated intraocular pressure in vivo.

Tuomela A, Liu P, Puranen J, Rönkkö S, Laaksonen T, Kalesnykas G, Oksala O, Ilkka J, Laru J, Järvinen K, Hirvonen J, Peltonen L.

Int J Pharm. 2014 Jun 5;467(1-2):34-41. doi: 10.1016/j.ijpharm.2014.03.048. Epub 2014 Mar 26.

PMID:
24680962
19.

Nanocrystal-based per-oral itraconazole delivery: superior in vitro dissolution enhancement versus Sporanox® is not realized in in vivo drug absorption.

Sarnes A, Kovalainen M, Häkkinen MR, Laaksonen T, Laru J, Kiesvaara J, Ilkka J, Oksala O, Rönkkö S, Järvinen K, Hirvonen J, Peltonen L.

J Control Release. 2014 Apr 28;180:109-16. doi: 10.1016/j.jconrel.2014.02.016. Epub 2014 Feb 22.

PMID:
24566254
20.

A genome-wide association study of anorexia nervosa.

Boraska V, Franklin CS, Floyd JA, Thornton LM, Huckins LM, Southam L, Rayner NW, Tachmazidou I, Klump KL, Treasure J, Lewis CM, Schmidt U, Tozzi F, Kiezebrink K, Hebebrand J, Gorwood P, Adan RA, Kas MJ, Favaro A, Santonastaso P, Fernández-Aranda F, Gratacos M, Rybakowski F, Dmitrzak-Weglarz M, Kaprio J, Keski-Rahkonen A, Raevuori A, Van Furth EF, Slof-Op 't Landt MC, Hudson JI, Reichborn-Kjennerud T, Knudsen GP, Monteleone P, Kaplan AS, Karwautz A, Hakonarson H, Berrettini WH, Guo Y, Li D, Schork NJ, Komaki G, Ando T, Inoko H, Esko T, Fischer K, Männik K, Metspalu A, Baker JH, Cone RD, Dackor J, DeSocio JE, Hilliard CE, O'Toole JK, Pantel J, Szatkiewicz JP, Taico C, Zerwas S, Trace SE, Davis OS, Helder S, Bühren K, Burghardt R, de Zwaan M, Egberts K, Ehrlich S, Herpertz-Dahlmann B, Herzog W, Imgart H, Scherag A, Scherag S, Zipfel S, Boni C, Ramoz N, Versini A, Brandys MK, Danner UN, de Kovel C, Hendriks J, Koeleman BP, Ophoff RA, Strengman E, van Elburg AA, Bruson A, Clementi M, Degortes D, Forzan M, Tenconi E, Docampo E, Escaramís G, Jiménez-Murcia S, Lissowska J, Rajewski A, Szeszenia-Dabrowska N, Slopien A, Hauser J, Karhunen L, Meulenbelt I, Slagboom PE, Tortorella A, Maj M, Dedoussis G, Dikeos D, Gonidakis F, Tziouvas K, Tsitsika A, Papezova H, Slachtova L, Martaskova D, Kennedy JL, Levitan RD, Yilmaz Z, Huemer J, Koubek D, Merl E, Wagner G, Lichtenstein P, Breen G, Cohen-Woods S, Farmer A, McGuffin P, Cichon S, Giegling I, Herms S, Rujescu D, Schreiber S, Wichmann HE, Dina C, Sladek R, Gambaro G, Soranzo N, Julia A, Marsal S, Rabionet R, Gaborieau V, Dick DM, Palotie A, Ripatti S, Widén E, Andreassen OA, Espeseth T, Lundervold A, Reinvang I, Steen VM, Le Hellard S, Mattingsdal M, Ntalla I, Bencko V, Foretova L, Janout V, Navratilova M, Gallinger S, Pinto D, Scherer SW, Aschauer H, Carlberg L, Schosser A, Alfredsson L, Ding B, Klareskog L, Padyukov L, Courtet P, Guillaume S, Jaussent I, Finan C, Kalsi G, Roberts M, Logan DW, Peltonen L, Ritchie GR, Barrett JC; Wellcome Trust Case Control Consortium 3, Estivill X, Hinney A, Sullivan PF, Collier DA, Zeggini E, Bulik CM.

Mol Psychiatry. 2014 Oct;19(10):1085-94. doi: 10.1038/mp.2013.187. Epub 2014 Feb 11.

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