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Items: 1 to 20 of 196

1.

Registered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.

Bhargava A, Pelech S, Woodard B, Kerwin J, Maherali N; Reproducibility Project: Cancer Biology; Reproducibility Project Cancer Biology.

Elife. 2016 Feb 16;5. pii: e09976. doi: 10.7554/eLife.09976.

2.

Regulatory roles of conserved phosphorylation sites in the activation T-loop of the MAP kinase ERK1.

Lai S, Pelech S.

Mol Biol Cell. 2016 Mar 15;27(6):1040-50. doi: 10.1091/mbc.E15-07-0527. Epub 2016 Jan 28.

3.

Evolutionary Ancestry of Eukaryotic Protein Kinases and Choline Kinases.

Lai S, Safaei J, Pelech S.

J Biol Chem. 2016 Mar 4;291(10):5199-205. doi: 10.1074/jbc.M115.691428. Epub 2016 Jan 7.

PMID:
26742849
4.

Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays.

Lai S, Winkler DF, Zhang H, Pelech S.

Methods Mol Biol. 2016;1360:183-202. doi: 10.1007/978-1-4939-3073-9_14.

PMID:
26501911
5.

Monitoring Protein Kinase Expression and Phosphorylation in Cell Lysates with Antibody Microarrays.

Zhang H, Shi X, Pelech S.

Methods Mol Biol. 2016;1360:107-22. doi: 10.1007/978-1-4939-3073-9_9.

PMID:
26501906
6.

Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein.

Binukumar BK, Shukla V, Amin ND, Bhaskar M, Skuntz S, Steiner J, Winkler D, Pelech SL, Pant HC.

J Alzheimers Dis. 2015;48(4):1009-17. doi: 10.3233/JAD-150412.

PMID:
26444778
7.

Profiling signaling proteins in human spermatozoa: biomarker identification for sperm quality evaluation.

Silva JV, Freitas MJ, Correia BR, Korrodi-Gregório L, Patrício A, Pelech S, Fardilha M.

Fertil Steril. 2015 Oct;104(4):845-856.e8. doi: 10.1016/j.fertnstert.2015.06.039. Epub 2015 Jul 23.

PMID:
26209830
8.

Post-ovulatory aging of oocytes disrupts kinase signaling pathways and lysosome biogenesis.

McGinnis LK, Pelech S, Kinsey WH.

Mol Reprod Dev. 2014 Oct;81(10):928-45. doi: 10.1002/mrd.22413. Epub 2014 Sep 19.

9.

"Omics" of human sperm: profiling protein phosphatases.

Fardilha M, Ferreira M, Pelech S, Vieira S, Rebelo S, Korrodi-Gregorio L, Sousa M, Barros A, Silva V, da Cruz e Silva OA, da Cruz e Silva EF.

OMICS. 2013 Sep;17(9):460-72. doi: 10.1089/omi.2012.0119. Epub 2013 Jul 29.

10.

Using protein microarrays to study phosphorylation-mediated signal transduction.

Zhang H, Pelech S.

Semin Cell Dev Biol. 2012 Oct;23(8):872-82. doi: 10.1016/j.semcdb.2012.05.009. Epub 2012 Jun 15. Review.

PMID:
22706299
11.

Prediction of 492 human protein kinase substrate specificities.

Safaei J, Maňuch J, Gupta A, Stacho L, Pelech S.

Proteome Sci. 2011 Oct 14;9 Suppl 1:S6. doi: 10.1186/1477-5956-9-S1-S6.

12.

Phosphoproteomic analysis of Salmonella-infected cells identifies key kinase regulators and SopB-dependent host phosphorylation events.

Rogers LD, Brown NF, Fang Y, Pelech S, Foster LJ.

Sci Signal. 2011 Sep 20;4(191):rs9. doi: 10.1126/scisignal.2001668.

13.

Proteomic analyses of lung lysates from short-term exposure of Fischer 344 rats to cigarette smoke.

Carter CA, Misra M, Pelech S.

J Proteome Res. 2011 Aug 5;10(8):3720-31. doi: 10.1021/pr200345y. Epub 2011 Jun 16.

PMID:
21627322
14.

YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification.

Davies AH, Barrett I, Pambid MR, Hu K, Stratford AL, Freeman S, Berquin IM, Pelech S, Hieter P, Maxwell C, Dunn SE.

Oncogene. 2011 Aug 25;30(34):3649-60. doi: 10.1038/onc.2011.82. Epub 2011 Mar 21.

15.

Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility.

Fardilha M, Esteves SL, Korrodi-Gregório L, Pelech S, da Cruz E Silva OA, da Cruz E Silva E.

Mol Hum Reprod. 2011 Aug;17(8):466-77. doi: 10.1093/molehr/gar004. Epub 2011 Jan 20. Review.

16.
17.

Sparse combinatorial inference with an application in cancer biology.

Mukherjee S, Pelech S, Neve RM, Kuo WL, Ziyad S, Spellman PT, Gray JW, Speed TP.

Bioinformatics. 2009 Jan 15;25(2):265-71. doi: 10.1093/bioinformatics/btn611. Epub 2008 Nov 27.

18.

Protein signaling pathways in differentiation of neural stem cells.

Skalnikova H, Vodicka P, Pelech S, Motlik J, Gadher SJ, Kovarova H.

Proteomics. 2008 Nov;8(21):4547-59. doi: 10.1002/pmic.200800096.

PMID:
18837464
19.

Pertussis toxin induces angiogenesis in brain microvascular endothelial cells.

Lu C, Pelech S, Zhang H, Bond J, Spach K, Noubade R, Blankenhorn EP, Teuscher C.

J Neurosci Res. 2008 Sep;86(12):2624-40. doi: 10.1002/jnr.21716.

PMID:
18500752
20.

Antibody microarray analyses of signal transduction protein expression and phosphorylation during porcine oocyte maturation.

Pelech S, Jelinkova L, Susor A, Zhang H, Shi X, Pavlok A, Kubelka M, Kovarova H.

J Proteome Res. 2008 Jul;7(7):2860-71. doi: 10.1021/pr800082a. Epub 2008 May 17.

PMID:
18484764
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