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Results: 1 to 20 of 1056

1.

A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals.

Krarup NT, Borglykke A, Allin KH, Sandholt CH, Justesen JM, Andersson EA, Grarup N, Jørgensen T, Pedersen O, Hansen T.

Atherosclerosis. 2015 Mar 16;240(2):305-310. doi: 10.1016/j.atherosclerosis.2015.03.022. [Epub ahead of print]

PMID:
25864160
2.

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.

Rönn T, Volkov P, Gillberg L, Kokosar M, Perfilyev A, Jacobsen AL, Jørgensen SW, Brøns C, Jansson PA, Eriksson KF, Pedersen O, Hansen T, Groop L, Stener-Victorin E, Vaag A, Nilsson E, Ling C.

Hum Mol Genet. 2015 Apr 10. pii: ddv124. [Epub ahead of print]

PMID:
25861810
3.

No association between iron status and self-reported health-related quality of life in 16,375 Danish blood donors: results from the Danish Blood Donor Study.

Rigas AS, Pedersen OB, Sørensen CJ, Sørensen E, Kotzé SR, Petersen MS, Thørner LW, Hjalgrim H, Erikstrup C, Ullum H.

Transfusion. 2015 Apr 6. doi: 10.1111/trf.13085. [Epub ahead of print]

PMID:
25851623
4.

The gut microbiome in cardio-metabolic health.

Hansen TH, Gøbel RJ, Hansen T, Pedersen O.

Genome Med. 2015 Mar 31;7(1):33. doi: 10.1186/s13073-015-0157-z. eCollection 2015. Review.

5.

Do patients with chronic rhinosinusitis benefit from consultation with an ENT-doctor?

Lange B, Thilsing T, Baelum J, Pedersen OF, Holst R, Kjeldsen AD.

Acta Otolaryngol. 2015 Mar 26:1-7. [Epub ahead of print]

PMID:
25813521
6.

The heritability of blood donation: a population-based nationwide twin study.

Pedersen OB, Axel S, Rostgaard K, Erikstrup C, Edgren G, Nielsen KR, Ullum H, Kyvik KO, Hjalgrim H.

Transfusion. 2015 Mar 21. doi: 10.1111/trf.13086. [Epub ahead of print]

PMID:
25808722
7.

The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes.

Harder MN, Appel EV, Grarup N, Gjesing AP, Ahluwalia TS, Jørgensen T, Christensen C, Brandslund I, Linneberg A, Sørensen TI, Pedersen O, Hansen T.

PLoS One. 2015 Mar 23;10(3):e0120890. doi: 10.1371/journal.pone.0120890. eCollection 2015.

8.

Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population.

Justesen JM, Allin KH, Sandholt CH, Borglykke A, Krarup NT, Grarup N, Linneberg A, Jørgensen T, Hansen T, Pedersen O.

Circ Cardiovasc Genet. 2015 Feb 24. pii: CIRCGENETICS.114.000637. [Epub ahead of print]

PMID:
25714099
9.

Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes.

Nolan CJ, Ruderman NB, Kahn SE, Pedersen O, Prentki M.

Diabetes. 2015 Mar;64(3):673-86. doi: 10.2337/db14-0694. Review.

PMID:
25713189
10.

Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study.

Færch K, Torekov SS, Vistisen D, Johansen NB, Witte DR, Jonsson A, Pedersen O, Hansen T, Lauritzen T, Sandbæk A, Holst JJ, Jørgensen ME.

Diabetes. 2015 Feb 12. pii: db141751. [Epub ahead of print]

PMID:
25677912
11.

The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample.

Esserlind AL, Christensen AF, Steinberg S, Grarup N, Pedersen O, Hansen T, Werge T, Hansen TF, Husemoen LL, Linneberg A, Budtz-Jorgensen E, Westergaard ML, Stefansson H, Olesen J.

Cephalalgia. 2015 Feb 9. pii: 0333102415570492. [Epub ahead of print]

PMID:
25667298
12.

Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data.

Gjesing AP, Ribel-Madsen R, Harder MN, Eiberg H, Grarup N, Jørgensen T, Ekstrøm CT, Pedersen O, Hansen T.

Diabetologia. 2015 May;58(5):1006-12. doi: 10.1007/s00125-015-3516-9. Epub 2015 Feb 9.

PMID:
25660259
13.

Predictors of hemoglobin in Danish blood donors: results from the Danish Blood Donor Study.

Kotzé SR, Pedersen OB, Petersen MS, Sørensen E, Thørner LW, Sørensen CJ, Rigas AS, Hjalgrim H, Rostgaard K, Ullum H, Erikstrup C.

Transfusion. 2015 Feb 3. doi: 10.1111/trf.13011. [Epub ahead of print]

PMID:
25647099
14.

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, Rasmussen-Torvik LJ, Grarup N, Ehm MG, Li L, Baldridge AS, Stančáková A, Abrol R, Besse C, Boland A, Bork-Jensen J, Fornage M, Freitag DF, Garcia ME, Guo X, Hara K, Isaacs A, Jakobsdottir J, Lange LA, Layton JC, Li M, Hua Zhao J, Meidtner K, Morrison AC, Nalls MA, Peters MJ, Sabater-Lleal M, Schurmann C, Silveira A, Smith AV, Southam L, Stoiber MH, Strawbridge RJ, Taylor KD, Varga TV, Allin KH, Amin N, Aponte JL, Aung T, Barbieri C, Bihlmeyer NA, Boehnke M, Bombieri C, Bowden DW, Burns SM, Chen Y, Chen YD, Cheng CY, Correa A, Czajkowski J, Dehghan A, Ehret GB, Eiriksdottir G, Escher SA, Farmaki AE, Frånberg M, Gambaro G, Giulianini F, Goddard WA 3rd, Goel A, Gottesman O, Grove ML, Gustafsson S, Hai Y, Hallmans G, Heo J, Hoffmann P, Ikram MK, Jensen RA, Jørgensen ME, Jørgensen T, Karaleftheri M, Khor CC, Kirkpatrick A, Kraja AT, Kuusisto J, Lange EM, Lee IT, Lee WJ, Leong A, Liao J, Liu C, Liu Y, Lindgren CM, Linneberg A, Malerba G, Mamakou V, Marouli E, Maruthur NM, Matchan A, McKean-Cowdin R, McLeod O, Metcalf GA, Mohlke KL, Muzny DM, Ntalla I, Palmer ND, Pasko D, Peter A, Rayner NW, Renström F, Rice K, Sala CF, Sennblad B, Serafetinidis I, Smith JA, Soranzo N, Speliotes EK, Stahl EA, Stirrups K, Tentolouris N, Thanopoulou A, Torres M, Traglia M, Tsafantakis E, Javad S, Yanek LR, Zengini E, Becker DM, Bis JC, Brown JB, Cupples LA, Hansen T, Ingelsson E, Karter AJ, Lorenzo C, Mathias RA, Norris JM, Peloso GM, Sheu WH, Toniolo D, Vaidya D, Varma R, Wagenknecht LE, Boeing H, Bottinger EP, Dedoussis G, Deloukas P, Ferrannini E, Franco OH, Franks PW, Gibbs RA, Gudnason V, Hamsten A, Harris TB, Hattersley AT, Hayward C, Hofman A, Jansson JH, Langenberg C, Launer LJ, Levy D, Oostra BA, O'Donnell CJ, O'Rahilly S, Padmanabhan S, Pankow JS, Polasek O, Province MA, Rich SS, Ridker PM, Rudan I, Schulze MB, Smith BH, Uitterlinden AG, Walker M, Watkins H, Wong TY, Zeggini E; EPIC-InterAct Consortium, Laakso M, Borecki IB, Chasman DI, Pedersen O, Psaty BM, Tai ES, van Duijn CM, Wareham NJ, Waterworth DM, Boerwinkle E, Kao WH, Florez JC, Loos RJ, Wilson JG, Frayling TM, Siscovick DS, Dupuis J, Rotter JI, Meigs JB, Scott RA, Goodarzi MO.

Nat Commun. 2015 Jan 29;6:5897. doi: 10.1038/ncomms6897.

15.

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.

Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, Rayner NW, Robertson NR, Beer NL, Rundle JK, Bork-Jensen J, Ladenvall C, Blancher C, Buck D, Buck G, Burtt NP, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Syvänen AC, Trakalo J, Abecasis G, Bell GI, Blangero J, Cox NJ, Duggirala R, Hanis CL, Seielstad M, Wilson JG, Christensen C, Brandslund I, Rauramaa R, Surdulescu GL, Doney AS, Lannfelt L, Linneberg A, Isomaa B, Tuomi T, Jørgensen ME, Jørgensen T, Kuusisto J, Uusitupa M, Salomaa V, Spector TD, Morris AD, Palmer CN, Collins FS, Mohlke KL, Bergman RN, Ingelsson E, Lind L, Tuomilehto J, Hansen T, Watanabe RM, Prokopenko I, Dupuis J, Karpe F, Groop L, Laakso M, Pedersen O, Florez JC, Morris AP, Altshuler D, Meigs JB, Boehnke M, McCarthy MI, Lindgren CM, Gloyn AL; T2D-GENES consortium and GoT2D consortium.

PLoS Genet. 2015 Jan 27;11(1):e1004876. doi: 10.1371/journal.pgen.1004876. eCollection 2015 Jan.

16.

Association analysis of 29,956 individuals confirms that a low frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion.

Yaghootkar H, Stancáková A, Freathy RM, Vangipurapu J, Weedon MN, Xie W, Wood AR, Ferrannini E, Mari A, Ring SM, Lawlor DA, Davey Smith G, Jørgensen T, Hansen T, Pedersen O, Steinthorsdottir V, Guðbjartsson DF, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Hattersley AT, Walker M, Morris AD, McCarthy MI, Palmer C, Laakso M, Frayling TM.

Diabetes. 2015 Jan 20. pii: db141456. [Epub ahead of print]

17.

Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes.

Ahluwalia TS, Allin KH, Sandholt CH, Sparsø TH, Jørgensen ME, Rowe M, Christensen C, Brandslund I, Lauritzen T, Linneberg A, Husemoen LL, Jørgensen T, Hansen T, Grarup N, Pedersen O.

J Clin Endocrinol Metab. 2015 Apr;100(4):E664-71. doi: 10.1210/jc.2014-3677. Epub 2015 Jan 19.

PMID:
25599387
18.

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios.

Besenbacher S, Liu S, Izarzugaza JM, Grove J, Belling K, Bork-Jensen J, Huang S, Als TD, Li S, Yadav R, Rubio-García A, Lescai F, Demontis D, Rao J, Ye W, Mailund T, Friborg RM, Pedersen CN, Xu R, Sun J, Liu H, Wang O, Cheng X, Flores D, Rydza E, Rapacki K, Damm Sørensen J, Chmura P, Westergaard D, Dworzynski P, Sørensen TI, Lund O, Hansen T, Xu X, Li N, Bolund L, Pedersen O, Eiberg H, Krogh A, Børglum AD, Brunak S, Kristiansen K, Schierup MH, Wang J, Gupta R, Villesen P, Rasmussen S.

Nat Commun. 2015 Jan 19;6:5969. doi: 10.1038/ncomms6969.

19.

The new Scandinavian Donations and Transfusions database (SCANDAT2): a blood safety resource with added versatility.

Edgren G, Rostgaard K, Vasan SK, Wikman A, Norda R, Pedersen OB, Erikstrup C, Nielsen KR, Titlestad K, Ullum H, Melbye M, Nyrén O, Hjalgrim H.

Transfusion. 2015 Jan 9. doi: 10.1111/trf.12986. [Epub ahead of print]

PMID:
25573303
20.

Uncovering the genetic history of the present-day Greenlandic population.

Moltke I, Fumagalli M, Korneliussen TS, Crawford JE, Bjerregaard P, Jørgensen ME, Grarup N, Gulløv HC, Linneberg A, Pedersen O, Hansen T, Nielsen R, Albrechtsen A.

Am J Hum Genet. 2015 Jan 8;96(1):54-69. doi: 10.1016/j.ajhg.2014.11.012. Epub 2014 Dec 31.

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