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Results: 1 to 20 of 90

1.

Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study.

Ribas A, Gonzalez R, Pavlick A, Hamid O, Gajewski TF, Daud A, Flaherty L, Logan T, Chmielowski B, Lewis K, Kee D, Boasberg P, Yin M, Chan I, Musib L, Choong N, Puzanov I, McArthur GA.

Lancet Oncol. 2014 Aug;15(9):954-65. doi: 10.1016/S1470-2045(14)70301-8. Epub 2014 Jul 15.

PMID:
25037139
[PubMed - in process]
2.

Dose Selection, Pharmacokinetics, and Pharmacodynamics of BRAF Inhibitor Dabrafenib (GSK2118436).

Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau HT, Brown MP, Hamid O, Infante JR, Millward M, Pavlick A, Chin MT, O'Day SJ, Blackman SC, Curtis CM, Lebowitz P, Ma B, Ouellet D, Kefford RF.

Clin Cancer Res. 2014 Sep 1;20(17):4449-58. doi: 10.1158/1078-0432.CCR-14-0887. Epub 2014 Jun 23.

PMID:
24958809
[PubMed - in process]
3.

A phase 2 randomised study of ramucirumab (IMC-1121B) with or without dacarbazine in patients with metastatic melanoma.

Carvajal RD, Wong MK, Thompson JA, Gordon MS, Lewis KD, Pavlick AC, Wolchok JD, Rojas PB, Schwartz JD, Bedikian AY.

Eur J Cancer. 2014 Aug;50(12):2099-107. doi: 10.1016/j.ejca.2014.03.289. Epub 2014 Jun 12.

PMID:
24930625
[PubMed - indexed for MEDLINE]
4.

Enhanced immunohistochemical detection of neural infiltration in primary melanoma: is there a clinical value?

Scanlon P, Tian J, Zhong J, Silva I, Shapiro R, Pavlick A, Berman R, Osman I, Darvishian F.

Hum Pathol. 2014 Aug;45(8):1656-63. doi: 10.1016/j.humpath.2014.04.003. Epub 2014 Apr 18.

PMID:
24890944
[PubMed - indexed for MEDLINE]
5.

Update on vaccines for high-risk melanoma.

Weiss SA, Chandra S, Pavlick AC.

Curr Treat Options Oncol. 2014 Jun;15(2):269-80. doi: 10.1007/s11864-014-0283-7.

PMID:
24788575
[PubMed - in process]
6.

A single-arm, open-label, expanded access study of vemurafenib in patients with metastatic melanoma in the United States.

Flaherty L, Hamid O, Linette G, Schuchter L, Hallmeyer S, Gonzalez R, Cowey CL, Pavlick A, Kudrik F, Curti B, Lawson D, Chapman PB, Margolin K, Ribas A, McDermott D, Flaherty K, Cranmer L, Hodi FS, Day BM, Linke R, Hainsworth J.

Cancer J. 2014 Jan-Feb;20(1):18-24. doi: 10.1097/PPO.0000000000000024.

PMID:
24445759
[PubMed - in process]
7.

Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo.

O'Reilly KE, de Miera EV, Segura MF, Friedman E, Poliseno L, Han SW, Zhong J, Zavadil J, Pavlick A, Hernando E, Osman I.

Pharmaceuticals (Basel). 2013 Nov 11;6(11):1429-50. doi: 10.3390/ph6111429.

PMID:
24287465
[PubMed]
Free PMC Article
8.

Melanoma risk loci as determinants of melanoma recurrence and survival.

Rendleman J, Shang S, Dominianni C, Shields JF, Scanlon P, Adaniel C, Desrichard A, Ma M, Shapiro R, Berman R, Pavlick A, Polsky D, Shao Y, Osman I, Kirchhoff T.

J Transl Med. 2013 Nov 4;11:279. doi: 10.1186/1479-5876-11-279.

PMID:
24188633
[PubMed - in process]
Free Article
9.

Radiation-related cancer risk associated with radiographic imaging.

Finger PT, Freton A, Pavlick A.

JAMA Ophthalmol. 2013 Sep;131(9):1248-9. doi: 10.1001/jamaophthalmol.2013.4025. No abstract available.

PMID:
24030341
[PubMed - indexed for MEDLINE]
10.

Impact of age on the management of primary melanoma patients.

Fleming NH, Tian J, Vega-Saenz de Miera E, Gold H, Darvishian F, Pavlick AC, Berman RS, Shapiro RL, Polsky D, Osman I.

Oncology. 2013;85(3):173-81. doi: 10.1159/000351499. Epub 2013 Aug 30.

PMID:
24008821
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma.

Kaufman HL, Kirkwood JM, Hodi FS, Agarwala S, Amatruda T, Bines SD, Clark JI, Curti B, Ernstoff MS, Gajewski T, Gonzalez R, Hyde LJ, Lawson D, Lotze M, Lutzky J, Margolin K, McDermott DF, Morton D, Pavlick A, Richards JM, Sharfman W, Sondak VK, Sosman J, Steel S, Tarhini A, Thompson JA, Titze J, Urba W, White R, Atkins MB.

Nat Rev Clin Oncol. 2013 Oct;10(10):588-98. doi: 10.1038/nrclinonc.2013.153. Epub 2013 Aug 27.

PMID:
23982524
[PubMed - indexed for MEDLINE]
12.

Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor dabrafenib (GSK2118436).

Nathanson KL, Martin AM, Wubbenhorst B, Greshock J, Letrero R, D'Andrea K, O'Day S, Infante JR, Falchook GS, Arkenau HT, Millward M, Brown MP, Pavlick A, Davies MA, Ma B, Gagnon R, Curtis M, Lebowitz PF, Kefford R, Long GV.

Clin Cancer Res. 2013 Sep 1;19(17):4868-78. doi: 10.1158/1078-0432.CCR-13-0827. Epub 2013 Jul 5.

PMID:
23833299
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Development of acneiform rash does not predict response to lapatinib treatment in patients with breast cancer.

Parma J, Pavlick A, Schiff R, Osborne CK, Chang JC, Rimawi M, Trivedi MV.

Pharmacotherapy. 2013 Oct;33(10):1126-9. doi: 10.1002/phar.1308. Epub 2013 Jun 6.

PMID:
23744830
[PubMed - indexed for MEDLINE]
14.

A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models.

Zhang X, Claerhout S, Prat A, Dobrolecki LE, Petrovic I, Lai Q, Landis MD, Wiechmann L, Schiff R, Giuliano M, Wong H, Fuqua SW, Contreras A, Gutierrez C, Huang J, Mao S, Pavlick AC, Froehlich AM, Wu MF, Tsimelzon A, Hilsenbeck SG, Chen ES, Zuloaga P, Shaw CA, Rimawi MF, Perou CM, Mills GB, Chang JC, Lewis MT.

Cancer Res. 2013 Aug 1;73(15):4885-97. doi: 10.1158/0008-5472.CAN-12-4081. Epub 2013 Jun 4.

PMID:
23737486
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mitotic rate in melanoma: prognostic value of immunostaining and computer-assisted image analysis.

Hale CS, Qian M, Ma MW, Scanlon P, Berman RS, Shapiro RL, Pavlick AC, Shao Y, Polsky D, Osman I, Darvishian F.

Am J Surg Pathol. 2013 Jun;37(6):882-9. doi: 10.1097/PAS.0b013e31827e50fa.

PMID:
23629443
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Vemurafenib and radiation therapy in melanoma brain metastases.

Narayana A, Mathew M, Tam M, Kannan R, Madden KM, Golfinos JG, Parker EC, Ott PA, Pavlick AC.

J Neurooncol. 2013 Jul;113(3):411-6. doi: 10.1007/s11060-013-1127-1. Epub 2013 Apr 12.

PMID:
23579338
[PubMed - indexed for MEDLINE]
17.

Multicenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal therapy and without chemotherapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer: TBCRC 006.

Rimawi MF, Mayer IA, Forero A, Nanda R, Goetz MP, Rodriguez AA, Pavlick AC, Wang T, Hilsenbeck SG, Gutierrez C, Schiff R, Osborne CK, Chang JC.

J Clin Oncol. 2013 May 10;31(14):1726-31. doi: 10.1200/JCO.2012.44.8027. Epub 2013 Apr 8.

PMID:
23569315
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma.

Trunzer K, Pavlick AC, Schuchter L, Gonzalez R, McArthur GA, Hutson TE, Moschos SJ, Flaherty KT, Kim KB, Weber JS, Hersey P, Long GV, Lawrence D, Ott PA, Amaravadi RK, Lewis KD, Puzanov I, Lo RS, Koehler A, Kockx M, Spleiss O, Schell-Steven A, Gilbert HN, Cockey L, Bollag G, Lee RJ, Joe AK, Sosman JA, Ribas A.

J Clin Oncol. 2013 May 10;31(14):1767-74. doi: 10.1200/JCO.2012.44.7888. Epub 2013 Apr 8.

PMID:
23569304
[PubMed - indexed for MEDLINE]
Free Article
19.

Ipilimumab in melanoma with limited brain metastases treated with stereotactic radiosurgery.

Mathew M, Tam M, Ott PA, Pavlick AC, Rush SC, Donahue BR, Golfinos JG, Parker EC, Huang PP, Narayana A.

Melanoma Res. 2013 Jun;23(3):191-5. doi: 10.1097/CMR.0b013e32835f3d90.

PMID:
23462208
[PubMed - indexed for MEDLINE]
20.

Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor.

Kim KB, Kefford R, Pavlick AC, Infante JR, Ribas A, Sosman JA, Fecher LA, Millward M, McArthur GA, Hwu P, Gonzalez R, Ott PA, Long GV, Gardner OS, Ouellet D, Xu Y, DeMarini DJ, Le NT, Patel K, Lewis KD.

J Clin Oncol. 2013 Feb 1;31(4):482-9. doi: 10.1200/JCO.2012.43.5966. Epub 2012 Dec 17.

PMID:
23248257
[PubMed - indexed for MEDLINE]
Free Article

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