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Pathogenesis of neurotropic murine coronavirus is multifactorial.
Phillips JM, Weiss SR. Phillips JM, et al. Trends Pharmacol Sci. 2011 Jan;32(1):2-7. doi: 10.1016/j.tips.2010.11.001. Epub 2010 Dec 7. Trends Pharmacol Sci. 2011. PMID: 21144598 Free PMC article.
Although coronavirus tropism is most often ascribed to receptor availability, increasing evidence suggests that for the neurotropic strains of the murine coronavirus mouse hepatitis virus (MHV), spike-receptor interactions cannot fully ex …
Although coronavirus tropism is most often ascribed to receptor availability, increasing evidence suggests that for the neurotropi
Murine-beta-coronavirus-induced neuropathogenesis sheds light on CNS pathobiology of SARS-CoV2.
Chakravarty D, Das Sarma J. Chakravarty D, et al. J Neurovirol. 2021 Apr;27(2):197-216. doi: 10.1007/s13365-021-00945-5. Epub 2021 Feb 5. J Neurovirol. 2021. PMID: 33547593 Free PMC article. Review.
Simultaneously, considerable discussion on relevant experimental evidence of mild to severe neurological manifestations of fellow neurotropic murine-beta-CoVs (m-CoVs) in the mouse model will help understand the underpinning mechanisms of Neuro-COVID. ...These simil …
Simultaneously, considerable discussion on relevant experimental evidence of mild to severe neurological manifestations of fellow neurotr
Distinct Gene Profiles of Bone Marrow-Derived Macrophages and Microglia During Neurotropic Coronavirus-Induced Demyelination.
Savarin C, Dutta R, Bergmann CC. Savarin C, et al. Front Immunol. 2018 Jun 11;9:1325. doi: 10.3389/fimmu.2018.01325. eCollection 2018. Front Immunol. 2018. PMID: 29942315 Free PMC article.
Using a murine model of demyelination induced by a gliatropic coronavirus, in which BMDM are redundant for demyelination, we herein characterize gene expression profiles of BMDM versus microglia associated with demyelination. ...Overall, these data support a pro-inf …
Using a murine model of demyelination induced by a gliatropic coronavirus, in which BMDM are redundant for demyelination, we h …