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Results: 19

1.

Clopidogrel in infants with systemic-to-pulmonary-artery shunts.

Wessel DL, Berger F, Li JS, Dähnert I, Rakhit A, Fontecave S, Newburger JW; CLARINET Investigators.

N Engl J Med. 2013 Jun 20;368(25):2377-84. doi: 10.1056/NEJMoa1114588.

2.

The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs.

Watson NS, Adams C, Belton D, Brown D, Burns-Kurtis CL, Chaudry L, Chan C, Convery MA, Davies DE, Exall AM, Harling JD, Irvine S, Irving WR, Kleanthous S, McLay IM, Pateman AJ, Patikis AN, Roethke TJ, Senger S, Stelman GJ, Toomey JR, West RI, Whittaker C, Zhou P, Young RJ.

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1588-92. doi: 10.1016/j.bmcl.2011.01.129. Epub 2011 Feb 2.

PMID:
21349711
3.

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs.

Young RJ, Adams C, Blows M, Brown D, Burns-Kurtis CL, Chan C, Chaudry L, Convery MA, Davies DE, Exall AM, Foster G, Harling JD, Hortense E, Irvine S, Irving WR, Jackson S, Kleanthous S, Pateman AJ, Patikis AN, Roethka TJ, Senger S, Stelman GJ, Toomey JR, West RI, Whittaker C, Zhou P, Watson NS.

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1582-7. doi: 10.1016/j.bmcl.2011.01.131. Epub 2011 Feb 1.

PMID:
21349710
4.

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs.

Kleanthous S, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chan C, Clarte MO, Convery MA, Harling JD, Hortense E, Irving WR, Irvine S, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Roethka TJ, Senger S, Shah GP, Stelman GJ, Toomey JR, Watson NS, West RI, Whittaker C, Zhou P, Young RJ.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):618-22. doi: 10.1016/j.bmcl.2009.11.077. Epub 2009 Nov 20.

PMID:
20006499
5.

Prenatal cardiac ultrasound finding in congenital disorder of glycosylation type 1a.

Malhotra A, Pateman A, Chalmers R, Coman D, Menahem S.

Fetal Diagn Ther. 2009;25(1):54-7. doi: 10.1159/000196816. Epub 2009 Jan 29.

PMID:
19176971
6.

Antithrombotic potential of GW813893: a novel, orally active, active-site directed factor Xa inhibitor.

Abboud MA, Needle SJ, Burns-Kurtis CL, Valocik RE, Koster PF, Amour AJ, Chan C, Brown D, Chaudry L, Zhou P, Patikis A, Patel C, Pateman AJ, Young RJ, Watson NS, Toomey JR.

J Cardiovasc Pharmacol. 2008 Jul;52(1):66-71. doi: 10.1097/FJC.0b013e31817e9b9e.

PMID:
18645410
7.

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with biaryl P4 motifs.

Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Chung CW, Convery MA, Kelly HA, Paul King N, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):23-7. Epub 2007 Nov 17.

PMID:
18054228
8.

Structure and property based design of factor Xa inhibitors: biaryl pyrrolidin-2-ones incorporating basic heterocyclic motifs.

Young RJ, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chan C, Charbaut M, Convery MA, Diallo H, Hortense E, Irving WR, Kelly HA, King NP, Kleanthous S, Mason AM, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Zhou P.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):28-33. Epub 2007 Nov 13.

PMID:
18053714
9.

Selective and dual action orally active inhibitors of thrombin and factor Xa.

Young RJ, Brown D, Burns-Kurtis CL, Chan C, Convery MA, Hubbard JA, Kelly HA, Pateman AJ, Patikis A, Senger S, Shah GP, Toomey JR, Watson NS, Zhou P.

Bioorg Med Chem Lett. 2007 May 15;17(10):2927-30. Epub 2007 Mar 30.

PMID:
17420122
10.

Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides.

Chan C, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chung CW, Convery MA, Hamblin JN, Johnstone L, Kelly HA, Kleanthous S, Patikis A, Patel C, Pateman AJ, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Whitworth C, Young RJ, Zhou P.

J Med Chem. 2007 Apr 5;50(7):1546-57. Epub 2007 Mar 6.

PMID:
17338508
11.

Structure- and property-based design of factor Xa inhibitors: pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs.

Young RJ, Campbell M, Borthwick AD, Brown D, Burns-Kurtis CL, Chan C, Convery MA, Crowe MC, Dayal S, Diallo H, Kelly HA, King NP, Kleanthous S, Mason AM, Mordaunt JE, Patel C, Pateman AJ, Senger S, Shah GP, Smith PW, Watson NS, Weston HE, Zhou P.

Bioorg Med Chem Lett. 2006 Dec 1;16(23):5953-7. Epub 2006 Sep 18.

PMID:
16982190
12.

The determination of nicotinic acid in plasma by mixed-mode liquid chromatography-tandem mass spectrometry following ion exchange solid phase extraction.

Mallett DN, Dayal S, Dear GJ, Pateman AJ.

J Pharm Biomed Anal. 2006 May 3;41(2):510-6. Epub 2006 Jan 6.

PMID:
16406453
13.

Multiple nitrene insertions into metal-sulfur bonds of dithiocarbamate complexes: synthesis of sulfido-amido and zwitterionic tetraamido complexes.

Hogarth G, Holman KT, Pateman A, Sella A, Steed JW, Richards I.

Dalton Trans. 2005 Aug 21;(16):2688-95. Epub 2005 Jul 7.

PMID:
16075107
14.

Animal pharmacokinetics and interspecies scaling of sordarin derivatives following intravenous administration.

Aviles P, Pateman A, San Roman R, Guillén MJ, Gómez De Las Heras F, Gargallo-Viola D.

Antimicrob Agents Chemother. 2001 Oct;45(10):2787-92.

15.

A sensitive radioimmunoassay, incorporating solid-phase extraction, for fluticasone 17-propionate in plasma.

Bain BM, Harrison G, Jenkins KD, Pateman AJ, Shenoy EV.

J Pharm Biomed Anal. 1993 Jul;11(7):557-61.

PMID:
8399529
16.

Phase I and pharmacokinetic studies with the pentacyclic pyrroloquinone mitoquidone.

Speth PA, Gore ME, Pateman AJ, Newell DR, Bishop JA, Ellis WJ, Green JA, Gumbrell LA, Linssen PC, Miller A, et al.

Cancer Chemother Pharmacol. 1988;21(4):343-6.

PMID:
3370744
17.

Sensitive gas chromatographic method for the determination of alphadolone in plasma.

Pateman AJ.

J Chromatogr. 1981 Nov 13;226(1):213-8. No abstract available.

PMID:
7320145
18.

The uptake of spermidine and spermine by slices of mouse cerebral hemispheres.

Pateman AJ, Shaw GG.

J Neurochem. 1975 Sep;25(3):341-5. No abstract available.

PMID:
1159432
19.

The regional distribution of the polyamines spermidine and spermine in brain.

Shaw GG, Pateman AJ.

J Neurochem. 1973 Apr;20(4):1225-30. No abstract available.

PMID:
4697883
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